Whether to apply row-scaling on the matrix affects the clustering step in consensus partitioning, which might give different partition results on the samples. For the expression matrices, we recommend to scale rows because the more interesting thing is the subgrouping where genes show similar expression patterns in the sense of e.g. genes showing consistent up-regulation in the subgroups. If the rows are not scaled, the partitions are more generally affected by highly expressed genes.
In this analysis, we performed cola analysis on Golub Leukemia dataset by applying row-scaling on the matrix or not. The choice of row-scaling can be tuned by setting scale_rows to TRUE or FALSE in run_all_consensus_partition_methods() or consensus_partition() function.
For the partition methods hclust, kmeans, skmeans, pam and mclust, z-score scaling is applied as \((x-\mu)/\sigma\), and for NMF, the “min-max” scalling is applied as (x - min)/(max - min).
Figure 1A and 1B (switching the tabs in the following figure) illustrate consensus heatmaps for two-group classification with row-scaling or not. Table 1 lists the stability of consensus partition under different methods (measured by 1-PAC scores):
| Rows are scaled | Rows are unscaled | |
|---|---|---|
| ATC:skmeans | 1 | 0.67 |
| ATC:kmeans | 1 | 0.66 |
| ATC:NMF | 0.97 | 0.55 |
| SD:skmeans | 0.62 | 1 |
| CV:skmeans | 0.63 | 1 |
| MAD:skmeans | 0.64 | 1 |
| SD:kmeans | 0.66 | 1 |
| CV:kmeans | 0.65 | 1 |
| MAD:kmeans | 0.62 | 1 |
| CV:mclust | 0.49 | 0.98 |
| MAD:mclust | 0.82 | 0.96 |
| SD:mclust | 0.37 | 0.74 |
| CV:NMF | 0.63 | 0.68 |
| MAD:NMF | 0.68 | 0.65 |
| SD:NMF | 0.63 | 0.63 |
| SD:pam | 0.55 | 0.62 |
| MAD:pam | 0.65 | 0.58 |
| CV:pam | 0.55 | 0.55 |
| MAD:hclust | 0.23 | 0.53 |
| ATC:pam | 0.6 | 0.51 |
| SD:hclust | 0.24 | 0.44 |
| ATC:hclust | 0.57 | 0.4 |
| CV:hclust | 0.21 | 0.38 |
| ATC:mclust | 0.36 | 0.36 |
Figure 1A. Consensus heatmaps with two subgroups. Matrix rows are scaled.
Figure 1B. Consensus heatmaps with two subgroups. Matrix rows are unscaled.
Figure 2 put classifications from all 24 methods as well as one clinical annotation. The annotation ALL.AML tells whether the patient (the sample) had ALL or AML. The lightness of the main heatmap corresponds to the silhouette scores for samples measured in each partition method. With lighter color, the less stable for the sample to stay in the same group.
When the matrix rows are scaled (top heatmap in Figure 2), there are two major sets of different classifications where methods integrated with mclust, kmeans, and NMF classify samples into two groups where one group mainly contains AML samples. Other methods integrated with ATC, skmeans and pam generate classifications where a subset of ALL samples move to the same group of AML samples. Although there are two different two-group classifications, the samples that have different classifications among methods generally have lower silhouette scores in the corresponding consensus partition runs ( i.e. the colors in the heatmap are lighter), which means, they are less confident samples for the classifications and different partition methods might classify them into different groups.
When the matrix are not scaled (bottom heatmap in Figure 2), the pattern is similar that there are also two sets of classifications. The difference to the top heatmap is now the partitions where features are selected based on row variance (SD/CV/MAD) are more stable in the consensus partitioning procedure while partitions with features selected by ATC are less stable.
Comparing classifications from row-scaling and non-row-scaling, the classifications are similar for both cases. Basically we can make the conclusion that, when rows are scaled, methods with ATC give more stable partitions and when rows are not scaled, methods with SD/CV/MAD give more stable partitions.
Figure 2. Classifications from all methods. Column order of the two heatmaps are the same.
To look closer on the different impact on consensus partitioning of applying row-scaling or not, We select the results by ATC:skmeans for the case when matrix rows are scaled and the results by MAD:kmeans for the case when matrix rows are not scaled. The partitionings are stable for the two methods in their settings. Figure 3 illustrates how the two classifications correspond.
Figure 3. Conseusus partitions from ATC:skmeans and MAD:kmeans methods.
We can confirm that MAD:kmeans, row unscaled classification fits very well to the AML/ALL classification, while a subset of ALL samples are classified as the same group as AML samples for the ATC:skmeans, row scaled classification.
To make it easier to describe, we term the classification from the scaled matrix as \(C_{s, 2}\) and the classification from the unscaled matrix as \(C_{u, 2}\).
We can confirm the separation of the two groups by PCA visualization. PCA is applied to the scaled matrix in Figure 4A and to the unscaled matrix in Figure 4B. The two plots shows the two classifications can both separate samples very well and seem very reasonable.
Figure 4. PCA plots for visualizing the two-group classification.
Since there are two different classifications, we can next look at the signature genes that are significantly differentially expressed in the two groups, i.e. to compare the signature genes that support the two different classifications.
In Figure 5A and 5B, the significant genes are simply selected by t-test. According to the heatmaps illustrated in Figure 5A and 5B, it seems the two different classification are all reasonable that there are many genes supporting them, although the number of significant genes in \(C_{s,2}\) are approximate 2 fold more than that in \(C_{u,2}\).
Figure 5A. Signature genes from C_{s,2}.
Figure 5A. Signature genes from C_{u,2}.
The two sets of signature genes have quite large overlap, and they also have their own unique set of genes. \(C_{s,2}\) has 1106 (61%) specific genes and \(C_{u,2}\) has 353 (33%) specific genes (Figure 6).
Figure 6. Overlap of signature genes in C_{s,2} and C_{u,2}.
To see the difference of the three sets of signature genes in Figure 6, we make heatmaps for the signature genes specific in classification \(C_{s, 2}\), specific in \(C_{u, 2}\) and those common in the two classifications.
As illustrated in Figure 7A and 7C, the expression patterns for the signature genes specific in \(C_{s,2}\) or \(C_{u,2}\) are clean that the samples are not separable in the other classification, while in Figure 7B where the signature genes are shared by the two classifications, the signature genes show intermeidate expression patterns in the samples that disagree in the two classifcations, they can be classified to different groups by different methods.
Figure 7. Heatmaps of C_{s,2} specific signatures, C_{u,2} specific signatures and common signatures in the two classifcations.
We term the three categories of signature genes as group A/B/C and we apply Gene Ontology enrichment to the three set of genes by hypergenometric test (by the clusterProfiler package). We only use BP ontologies (Biological Process) and the significant GO terms are filtered by FDR < 0.01. The enriched GO terms are visualized as a heatmap in Figure 8 by their similarity to each other (by GOSemSim package). GO terms are split and categorized by their similarity clusters (see script here) with some of the terms highlighted as text.
Again, Figure 8 illustrates each set of genes have quite a lot enriched GO terms, which might imply both classification are biologically reasonable.
The complete list of the GO enrichment can be found at the end of this supplementary.
Figure 8. Gene ontology enrichment on the three sets of genes illustrated in Figure 7.
As a conclusion for the two-group classification analysis on Golub dataset, we can make following conclusions:
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0009725 | response to hormone | 111/877 | 920/17913 | 0.0000 | 0.0000 | 111 |
| GO:0051050 | positive regulation of transport | 111/877 | 942/17913 | 0.0000 | 0.0000 | 111 |
| GO:0010243 | response to organonitrogen compound | 105/877 | 932/17913 | 0.0000 | 0.0000 | 105 |
| GO:0071417 | cellular response to organonitrogen compound | 71/877 | 559/17913 | 0.0000 | 0.0000 | 71 |
| GO:0033993 | response to lipid | 95/877 | 884/17913 | 0.0000 | 0.0000 | 95 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 101/877 | 968/17913 | 0.0000 | 0.0000 | 101 |
| GO:1901652 | response to peptide | 64/877 | 491/17913 | 0.0000 | 0.0000 | 64 |
| GO:1901699 | cellular response to nitrogen compound | 74/877 | 620/17913 | 0.0000 | 0.0000 | 74 |
| GO:0014070 | response to organic cyclic compound | 93/877 | 879/17913 | 0.0000 | 0.0000 | 93 |
| GO:0023061 | signal release | 58/877 | 433/17913 | 0.0000 | 0.0000 | 58 |
| GO:0070482 | response to oxygen levels | 54/877 | 389/17913 | 0.0000 | 0.0000 | 54 |
| GO:0032870 | cellular response to hormone stimulus | 73/877 | 647/17913 | 0.0000 | 0.0000 | 73 |
| GO:1903530 | regulation of secretion by cell | 77/877 | 703/17913 | 0.0000 | 0.0000 | 77 |
| GO:0009611 | response to wounding | 74/877 | 665/17913 | 0.0000 | 0.0000 | 74 |
| GO:0042493 | response to drug | 95/877 | 958/17913 | 0.0000 | 0.0000 | 95 |
| GO:1901653 | cellular response to peptide | 50/877 | 364/17913 | 0.0000 | 0.0000 | 50 |
| GO:0051046 | regulation of secretion | 80/877 | 757/17913 | 0.0000 | 0.0000 | 80 |
| GO:0036293 | response to decreased oxygen levels | 49/877 | 365/17913 | 0.0000 | 0.0000 | 49 |
| GO:0001666 | response to hypoxia | 48/877 | 354/17913 | 0.0000 | 0.0000 | 48 |
| GO:0043434 | response to peptide hormone | 52/877 | 404/17913 | 0.0000 | 0.0000 | 52 |
| GO:0046879 | hormone secretion | 43/877 | 301/17913 | 0.0000 | 0.0000 | 43 |
| GO:0002790 | peptide secretion | 65/877 | 582/17913 | 0.0000 | 0.0000 | 65 |
| GO:0090087 | regulation of peptide transport | 74/877 | 706/17913 | 0.0000 | 0.0000 | 74 |
| GO:0051098 | regulation of binding | 48/877 | 368/17913 | 0.0000 | 0.0000 | 48 |
| GO:0030072 | peptide hormone secretion | 37/877 | 241/17913 | 0.0000 | 0.0000 | 37 |
| GO:0009914 | hormone transport | 43/877 | 311/17913 | 0.0000 | 0.0000 | 43 |
| GO:0019725 | cellular homeostasis | 81/877 | 814/17913 | 0.0000 | 0.0000 | 81 |
| GO:0042391 | regulation of membrane potential | 48/877 | 374/17913 | 0.0000 | 0.0000 | 48 |
| GO:0043269 | regulation of ion transport | 68/877 | 639/17913 | 0.0000 | 0.0000 | 68 |
| GO:0046883 | regulation of hormone secretion | 37/877 | 254/17913 | 0.0000 | 0.0000 | 37 |
| GO:0043066 | negative regulation of apoptotic process | 85/877 | 894/17913 | 0.0000 | 0.0000 | 85 |
| GO:0055082 | cellular chemical homeostasis | 69/877 | 666/17913 | 0.0000 | 0.0000 | 69 |
| GO:0098657 | import into cell | 75/877 | 751/17913 | 0.0000 | 0.0000 | 75 |
| GO:0061564 | axon development | 52/877 | 438/17913 | 0.0000 | 0.0000 | 52 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 69/877 | 669/17913 | 0.0000 | 0.0000 | 69 |
| GO:0032880 | regulation of protein localization | 90/877 | 979/17913 | 0.0000 | 0.0000 | 90 |
| GO:0007417 | central nervous system development | 87/877 | 935/17913 | 0.0000 | 0.0000 | 87 |
| GO:0007409 | axonogenesis | 48/877 | 393/17913 | 0.0000 | 0.0000 | 48 |
| GO:1903532 | positive regulation of secretion by cell | 47/877 | 381/17913 | 0.0000 | 0.0000 | 47 |
| GO:0071375 | cellular response to peptide hormone stimulus | 40/877 | 297/17913 | 0.0000 | 0.0000 | 40 |
| GO:0042327 | positive regulation of phosphorylation | 88/877 | 955/17913 | 0.0000 | 0.0000 | 88 |
| GO:0048732 | gland development | 50/877 | 422/17913 | 0.0000 | 0.0000 | 50 |
| GO:0060322 | head development | 73/877 | 738/17913 | 0.0000 | 0.0000 | 73 |
| GO:0046887 | positive regulation of hormone secretion | 24/877 | 125/17913 | 0.0000 | 0.0000 | 24 |
| GO:0043069 | negative regulation of programmed cell death | 85/877 | 916/17913 | 0.0000 | 0.0000 | 85 |
| GO:0099536 | synaptic signaling | 63/877 | 601/17913 | 0.0000 | 0.0000 | 63 |
| GO:0048534 | hematopoietic or lymphoid organ development | 83/877 | 890/17913 | 0.0000 | 0.0000 | 83 |
| GO:0090276 | regulation of peptide hormone secretion | 31/877 | 199/17913 | 0.0000 | 0.0000 | 31 |
| GO:0060341 | regulation of cellular localization | 81/877 | 863/17913 | 0.0000 | 0.0000 | 81 |
| GO:0002520 | immune system development | 86/877 | 938/17913 | 0.0000 | 0.0000 | 86 |
| GO:0007268 | chemical synaptic transmission | 62/877 | 591/17913 | 0.0000 | 0.0000 | 62 |
| GO:0098916 | anterograde trans-synaptic signaling | 62/877 | 591/17913 | 0.0000 | 0.0000 | 62 |
| GO:0048729 | tissue morphogenesis | 65/877 | 635/17913 | 0.0000 | 0.0000 | 65 |
| GO:0050804 | modulation of chemical synaptic transmission | 47/877 | 393/17913 | 0.0000 | 0.0000 | 47 |
| GO:0006936 | muscle contraction | 43/877 | 343/17913 | 0.0000 | 0.0000 | 43 |
| GO:0009636 | response to toxic substance | 55/877 | 499/17913 | 0.0000 | 0.0000 | 55 |
| GO:0099177 | regulation of trans-synaptic signaling | 47/877 | 394/17913 | 0.0000 | 0.0000 | 47 |
| GO:0008285 | negative regulation of cell proliferation | 73/877 | 751/17913 | 0.0000 | 0.0000 | 73 |
| GO:0070201 | regulation of establishment of protein localization | 71/877 | 723/17913 | 0.0000 | 0.0000 | 71 |
| GO:0099537 | trans-synaptic signaling | 62/877 | 596/17913 | 0.0000 | 0.0000 | 62 |
| GO:0048863 | stem cell differentiation | 34/877 | 237/17913 | 0.0000 | 0.0000 | 34 |
| GO:0051047 | positive regulation of secretion | 48/877 | 409/17913 | 0.0000 | 0.0000 | 48 |
| GO:0001505 | regulation of neurotransmitter levels | 41/877 | 321/17913 | 0.0000 | 0.0000 | 41 |
| GO:0010817 | regulation of hormone levels | 55/877 | 503/17913 | 0.0000 | 0.0000 | 55 |
| GO:0048511 | rhythmic process | 38/877 | 287/17913 | 0.0000 | 0.0000 | 38 |
| GO:0030097 | hemopoiesis | 79/877 | 847/17913 | 0.0000 | 0.0000 | 79 |
| GO:0032386 | regulation of intracellular transport | 47/877 | 400/17913 | 0.0000 | 0.0000 | 47 |
| GO:0032868 | response to insulin | 35/877 | 252/17913 | 0.0000 | 0.0000 | 35 |
| GO:0048545 | response to steroid hormone | 45/877 | 375/17913 | 0.0000 | 0.0000 | 45 |
| GO:0099003 | vesicle-mediated transport in synapse | 28/877 | 174/17913 | 0.0000 | 0.0000 | 28 |
| GO:0009306 | protein secretion | 58/877 | 549/17913 | 0.0000 | 0.0000 | 58 |
| GO:0072358 | cardiovascular system development | 75/877 | 792/17913 | 0.0000 | 0.0000 | 75 |
| GO:0044419 | interspecies interaction between organisms | 84/877 | 928/17913 | 0.0000 | 0.0000 | 84 |
| GO:0006935 | chemotaxis | 58/877 | 551/17913 | 0.0000 | 0.0000 | 58 |
| GO:0002791 | regulation of peptide secretion | 53/877 | 483/17913 | 0.0000 | 0.0000 | 53 |
| GO:0034762 | regulation of transmembrane transport | 57/877 | 538/17913 | 0.0000 | 0.0000 | 57 |
| GO:0042330 | taxis | 58/877 | 553/17913 | 0.0000 | 0.0000 | 58 |
| GO:0001944 | vasculature development | 74/877 | 784/17913 | 0.0000 | 0.0000 | 74 |
| GO:0035239 | tube morphogenesis | 82/877 | 905/17913 | 0.0000 | 0.0000 | 82 |
| GO:0003012 | muscle system process | 50/877 | 448/17913 | 0.0000 | 0.0000 | 50 |
| GO:0009743 | response to carbohydrate | 32/877 | 224/17913 | 0.0000 | 0.0000 | 32 |
| GO:0072507 | divalent inorganic cation homeostasis | 47/877 | 412/17913 | 0.0000 | 0.0000 | 47 |
| GO:0051223 | regulation of protein transport | 66/877 | 677/17913 | 0.0000 | 0.0000 | 66 |
| GO:0008284 | positive regulation of cell proliferation | 83/877 | 931/17913 | 0.0000 | 0.0000 | 83 |
| GO:0007420 | brain development | 67/877 | 694/17913 | 0.0000 | 0.0000 | 67 |
| GO:0006836 | neurotransmitter transport | 33/877 | 241/17913 | 0.0000 | 0.0000 | 33 |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 45/877 | 392/17913 | 0.0000 | 0.0000 | 45 |
| GO:0043270 | positive regulation of ion transport | 35/877 | 266/17913 | 0.0000 | 0.0000 | 35 |
| GO:0009266 | response to temperature stimulus | 31/877 | 219/17913 | 0.0000 | 0.0000 | 31 |
| GO:0001568 | blood vessel development | 70/877 | 751/17913 | 0.0000 | 0.0000 | 70 |
| GO:0016579 | protein deubiquitination | 34/877 | 260/17913 | 0.0000 | 0.0000 | 34 |
| GO:1904951 | positive regulation of establishment of protein localization | 48/877 | 440/17913 | 0.0000 | 0.0000 | 48 |
| GO:0032101 | regulation of response to external stimulus | 78/877 | 873/17913 | 0.0000 | 0.0000 | 78 |
| GO:0070646 | protein modification by small protein removal | 35/877 | 273/17913 | 0.0000 | 0.0000 | 35 |
| GO:0030001 | metal ion transport | 73/877 | 800/17913 | 0.0000 | 0.0000 | 73 |
| GO:0001934 | positive regulation of protein phosphorylation | 80/877 | 907/17913 | 0.0000 | 0.0000 | 80 |
| GO:0045471 | response to ethanol | 22/877 | 127/17913 | 0.0000 | 0.0000 | 22 |
| GO:0050878 | regulation of body fluid levels | 52/877 | 499/17913 | 0.0000 | 0.0000 | 52 |
| GO:0048514 | blood vessel morphogenesis | 64/877 | 670/17913 | 0.0000 | 0.0000 | 64 |
| GO:0033674 | positive regulation of kinase activity | 55/877 | 541/17913 | 0.0000 | 0.0000 | 55 |
| GO:0010959 | regulation of metal ion transport | 42/877 | 365/17913 | 0.0000 | 0.0000 | 42 |
| GO:0018209 | peptidyl-serine modification | 33/877 | 252/17913 | 0.0000 | 0.0000 | 33 |
| GO:0046677 | response to antibiotic | 39/877 | 328/17913 | 0.0000 | 0.0000 | 39 |
| GO:0044403 | symbiont process | 78/877 | 884/17913 | 0.0000 | 0.0000 | 78 |
| GO:0050778 | positive regulation of immune response | 73/877 | 809/17913 | 0.0000 | 0.0000 | 73 |
| GO:0009894 | regulation of catabolic process | 80/877 | 916/17913 | 0.0000 | 0.0000 | 80 |
| GO:0003013 | circulatory system process | 54/877 | 532/17913 | 0.0000 | 0.0000 | 54 |
| GO:0030003 | cellular cation homeostasis | 53/877 | 518/17913 | 0.0000 | 0.0000 | 53 |
| GO:0071407 | cellular response to organic cyclic compound | 54/877 | 533/17913 | 0.0000 | 0.0000 | 54 |
| GO:0001525 | angiogenesis | 57/877 | 576/17913 | 0.0000 | 0.0000 | 57 |
| GO:0090277 | positive regulation of peptide hormone secretion | 18/877 | 91/17913 | 0.0000 | 0.0000 | 18 |
| GO:2001233 | regulation of apoptotic signaling pathway | 44/877 | 397/17913 | 0.0000 | 0.0000 | 44 |
| GO:0031329 | regulation of cellular catabolic process | 73/877 | 814/17913 | 0.0000 | 0.0000 | 73 |
| GO:0097190 | apoptotic signaling pathway | 57/877 | 579/17913 | 0.0000 | 0.0000 | 57 |
| GO:0006875 | cellular metal ion homeostasis | 49/877 | 467/17913 | 0.0000 | 0.0000 | 49 |
| GO:0048608 | reproductive structure development | 46/877 | 426/17913 | 0.0000 | 0.0000 | 46 |
| GO:0051347 | positive regulation of transferase activity | 59/877 | 609/17913 | 0.0000 | 0.0000 | 59 |
| GO:0055074 | calcium ion homeostasis | 43/877 | 388/17913 | 0.0000 | 0.0000 | 43 |
| GO:0061458 | reproductive system development | 46/877 | 429/17913 | 0.0000 | 0.0000 | 46 |
| GO:0030073 | insulin secretion | 28/877 | 200/17913 | 0.0000 | 0.0000 | 28 |
| GO:0034284 | response to monosaccharide | 28/877 | 200/17913 | 0.0000 | 0.0000 | 28 |
| GO:0000165 | MAPK cascade | 77/877 | 882/17913 | 0.0000 | 0.0000 | 77 |
| GO:0007507 | heart development | 55/877 | 556/17913 | 0.0000 | 0.0000 | 55 |
| GO:0048667 | cell morphogenesis involved in neuron differentiation | 51/877 | 500/17913 | 0.0000 | 0.0000 | 51 |
| GO:0071453 | cellular response to oxygen levels | 31/877 | 237/17913 | 0.0000 | 0.0000 | 31 |
| GO:0031347 | regulation of defense response | 77/877 | 885/17913 | 0.0000 | 0.0000 | 77 |
| GO:0071363 | cellular response to growth factor stimulus | 63/877 | 674/17913 | 0.0000 | 0.0000 | 63 |
| GO:0009749 | response to glucose | 27/877 | 190/17913 | 0.0000 | 0.0000 | 27 |
| GO:0023014 | signal transduction by protein phosphorylation | 77/877 | 886/17913 | 0.0000 | 0.0000 | 77 |
| GO:1902803 | regulation of synaptic vesicle transport | 16/877 | 76/17913 | 0.0000 | 0.0000 | 16 |
| GO:0002793 | positive regulation of peptide secretion | 34/877 | 275/17913 | 0.0000 | 0.0000 | 34 |
| GO:0006873 | cellular ion homeostasis | 53/877 | 531/17913 | 0.0000 | 0.0000 | 53 |
| GO:0000904 | cell morphogenesis involved in differentiation | 60/877 | 632/17913 | 0.0000 | 0.0000 | 60 |
| GO:0002253 | activation of immune response | 61/877 | 647/17913 | 0.0000 | 0.0000 | 61 |
| GO:0042593 | glucose homeostasis | 30/877 | 227/17913 | 0.0000 | 0.0000 | 30 |
| GO:0071396 | cellular response to lipid | 56/877 | 576/17913 | 0.0000 | 0.0000 | 56 |
| GO:0009755 | hormone-mediated signaling pathway | 29/877 | 216/17913 | 0.0000 | 0.0000 | 29 |
| GO:0033500 | carbohydrate homeostasis | 30/877 | 228/17913 | 0.0000 | 0.0000 | 30 |
| GO:0006942 | regulation of striated muscle contraction | 18/877 | 96/17913 | 0.0000 | 0.0000 | 18 |
| GO:0043065 | positive regulation of apoptotic process | 61/877 | 652/17913 | 0.0000 | 0.0000 | 61 |
| GO:0044057 | regulation of system process | 57/877 | 594/17913 | 0.0000 | 0.0000 | 57 |
| GO:0031667 | response to nutrient levels | 48/877 | 466/17913 | 0.0000 | 0.0000 | 48 |
| GO:1903522 | regulation of blood circulation | 35/877 | 292/17913 | 0.0000 | 0.0000 | 35 |
| GO:0009887 | animal organ morphogenesis | 83/877 | 989/17913 | 0.0000 | 0.0000 | 83 |
| GO:0008015 | blood circulation | 52/877 | 523/17913 | 0.0000 | 0.0000 | 52 |
| GO:0009746 | response to hexose | 27/877 | 195/17913 | 0.0000 | 0.0000 | 27 |
| GO:0018105 | peptidyl-serine phosphorylation | 30/877 | 231/17913 | 0.0000 | 0.0000 | 30 |
| GO:0016032 | viral process | 72/877 | 822/17913 | 0.0000 | 0.0000 | 72 |
| GO:0002009 | morphogenesis of an epithelium | 52/877 | 527/17913 | 0.0000 | 0.0000 | 52 |
| GO:0032869 | cellular response to insulin stimulus | 27/877 | 197/17913 | 0.0000 | 0.0000 | 27 |
| GO:0006874 | cellular calcium ion homeostasis | 41/877 | 375/17913 | 0.0000 | 0.0000 | 41 |
| GO:0070848 | response to growth factor | 64/877 | 704/17913 | 0.0000 | 0.0000 | 64 |
| GO:0001816 | cytokine production | 68/877 | 765/17913 | 0.0000 | 0.0001 | 68 |
| GO:0043068 | positive regulation of programmed cell death | 61/877 | 660/17913 | 0.0000 | 0.0001 | 61 |
| GO:0051222 | positive regulation of protein transport | 43/877 | 403/17913 | 0.0000 | 0.0001 | 43 |
| GO:0071214 | cellular response to abiotic stimulus | 36/877 | 310/17913 | 0.0000 | 0.0001 | 36 |
| GO:0104004 | cellular response to environmental stimulus | 36/877 | 310/17913 | 0.0000 | 0.0001 | 36 |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 55/877 | 573/17913 | 0.0000 | 0.0001 | 55 |
| GO:0000902 | cell morphogenesis | 75/877 | 874/17913 | 0.0000 | 0.0001 | 75 |
| GO:0055080 | cation homeostasis | 56/877 | 588/17913 | 0.0000 | 0.0001 | 56 |
| GO:0048812 | neuron projection morphogenesis | 54/877 | 559/17913 | 0.0000 | 0.0001 | 54 |
| GO:0006887 | exocytosis | 74/877 | 862/17913 | 0.0000 | 0.0001 | 74 |
| GO:0048858 | cell projection morphogenesis | 55/877 | 577/17913 | 0.0000 | 0.0001 | 55 |
| GO:0015672 | monovalent inorganic cation transport | 48/877 | 477/17913 | 0.0000 | 0.0001 | 48 |
| GO:0007187 | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 25/877 | 178/17913 | 0.0000 | 0.0001 | 25 |
| GO:0042060 | wound healing | 53/877 | 550/17913 | 0.0000 | 0.0001 | 53 |
| GO:0060627 | regulation of vesicle-mediated transport | 48/877 | 480/17913 | 0.0000 | 0.0001 | 48 |
| GO:0040007 | growth | 79/877 | 948/17913 | 0.0000 | 0.0001 | 79 |
| GO:0001101 | response to acid chemical | 37/877 | 330/17913 | 0.0000 | 0.0001 | 37 |
| GO:0070838 | divalent metal ion transport | 46/877 | 454/17913 | 0.0000 | 0.0001 | 46 |
| GO:0045786 | negative regulation of cell cycle | 57/877 | 613/17913 | 0.0000 | 0.0001 | 57 |
| GO:0007568 | aging | 36/877 | 318/17913 | 0.0000 | 0.0001 | 36 |
| GO:0009991 | response to extracellular stimulus | 49/877 | 498/17913 | 0.0000 | 0.0001 | 49 |
| GO:0009408 | response to heat | 23/877 | 158/17913 | 0.0000 | 0.0001 | 23 |
| GO:0043393 | regulation of protein binding | 28/877 | 217/17913 | 0.0000 | 0.0001 | 28 |
| GO:0098771 | inorganic ion homeostasis | 56/877 | 600/17913 | 0.0000 | 0.0001 | 56 |
| GO:0022898 | regulation of transmembrane transporter activity | 30/877 | 242/17913 | 0.0000 | 0.0001 | 30 |
| GO:0006941 | striated muscle contraction | 24/877 | 170/17913 | 0.0000 | 0.0001 | 24 |
| GO:0048771 | tissue remodeling | 24/877 | 170/17913 | 0.0000 | 0.0001 | 24 |
| GO:0048489 | synaptic vesicle transport | 20/877 | 126/17913 | 0.0000 | 0.0001 | 20 |
| GO:0097480 | establishment of synaptic vesicle localization | 20/877 | 126/17913 | 0.0000 | 0.0001 | 20 |
| GO:0072511 | divalent inorganic cation transport | 46/877 | 458/17913 | 0.0000 | 0.0001 | 46 |
| GO:0097479 | synaptic vesicle localization | 21/877 | 137/17913 | 0.0000 | 0.0001 | 21 |
| GO:0045860 | positive regulation of protein kinase activity | 49/877 | 501/17913 | 0.0000 | 0.0001 | 49 |
| GO:0000375 | RNA splicing, via transesterification reactions | 38/877 | 348/17913 | 0.0000 | 0.0001 | 38 |
| GO:2000736 | regulation of stem cell differentiation | 19/877 | 116/17913 | 0.0000 | 0.0001 | 19 |
| GO:0055065 | metal ion homeostasis | 51/877 | 531/17913 | 0.0000 | 0.0001 | 51 |
| GO:0031175 | neuron projection development | 74/877 | 879/17913 | 0.0000 | 0.0001 | 74 |
| GO:0010942 | positive regulation of cell death | 63/877 | 710/17913 | 0.0000 | 0.0001 | 63 |
| GO:0036294 | cellular response to decreased oxygen levels | 28/877 | 220/17913 | 0.0000 | 0.0001 | 28 |
| GO:0003015 | heart process | 33/877 | 284/17913 | 0.0000 | 0.0001 | 33 |
| GO:0009308 | amine metabolic process | 20/877 | 128/17913 | 0.0000 | 0.0001 | 20 |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 23/877 | 162/17913 | 0.0000 | 0.0001 | 23 |
| GO:0050801 | ion homeostasis | 60/877 | 669/17913 | 0.0000 | 0.0001 | 60 |
| GO:1904062 | regulation of cation transmembrane transport | 35/877 | 312/17913 | 0.0000 | 0.0001 | 35 |
| GO:0098655 | cation transmembrane transport | 64/877 | 730/17913 | 0.0000 | 0.0001 | 64 |
| GO:0007411 | axon guidance | 27/877 | 210/17913 | 0.0000 | 0.0001 | 27 |
| GO:0071456 | cellular response to hypoxia | 27/877 | 210/17913 | 0.0000 | 0.0001 | 27 |
| GO:0032990 | cell part morphogenesis | 55/877 | 595/17913 | 0.0000 | 0.0001 | 55 |
| GO:0030855 | epithelial cell differentiation | 65/877 | 746/17913 | 0.0000 | 0.0001 | 65 |
| GO:0051588 | regulation of neurotransmitter transport | 20/877 | 129/17913 | 0.0000 | 0.0001 | 20 |
| GO:0034764 | positive regulation of transmembrane transport | 26/877 | 199/17913 | 0.0000 | 0.0001 | 26 |
| GO:0050670 | regulation of lymphocyte proliferation | 26/877 | 199/17913 | 0.0000 | 0.0001 | 26 |
| GO:0008016 | regulation of heart contraction | 30/877 | 249/17913 | 0.0000 | 0.0001 | 30 |
| GO:0019221 | cytokine-mediated signaling pathway | 66/877 | 764/17913 | 0.0000 | 0.0001 | 66 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 28/877 | 224/17913 | 0.0000 | 0.0001 | 28 |
| GO:0006937 | regulation of muscle contraction | 23/877 | 164/17913 | 0.0000 | 0.0001 | 23 |
| GO:0007159 | leukocyte cell-cell adhesion | 36/877 | 328/17913 | 0.0000 | 0.0001 | 36 |
| GO:0097485 | neuron projection guidance | 27/877 | 212/17913 | 0.0000 | 0.0001 | 27 |
| GO:0009612 | response to mechanical stimulus | 26/877 | 200/17913 | 0.0000 | 0.0001 | 26 |
| GO:0032944 | regulation of mononuclear cell proliferation | 26/877 | 200/17913 | 0.0000 | 0.0001 | 26 |
| GO:0034765 | regulation of ion transmembrane transport | 45/877 | 453/17913 | 0.0000 | 0.0001 | 45 |
| GO:2000027 | regulation of animal organ morphogenesis | 30/877 | 250/17913 | 0.0000 | 0.0001 | 30 |
| GO:0098810 | neurotransmitter reuptake | 8/877 | 22/17913 | 0.0000 | 0.0001 | 8 |
| GO:0051101 | regulation of DNA binding | 19/877 | 120/17913 | 0.0000 | 0.0002 | 19 |
| GO:0006897 | endocytosis | 60/877 | 675/17913 | 0.0000 | 0.0002 | 60 |
| GO:2001020 | regulation of response to DNA damage stimulus | 26/877 | 201/17913 | 0.0000 | 0.0002 | 26 |
| GO:0045087 | innate immune response | 74/877 | 893/17913 | 0.0000 | 0.0002 | 74 |
| GO:0045055 | regulated exocytosis | 66/877 | 768/17913 | 0.0000 | 0.0002 | 66 |
| GO:0098660 | inorganic ion transmembrane transport | 63/877 | 722/17913 | 0.0000 | 0.0002 | 63 |
| GO:0006954 | inflammatory response | 67/877 | 784/17913 | 0.0000 | 0.0002 | 67 |
| GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 37/877 | 344/17913 | 0.0000 | 0.0002 | 37 |
| GO:0000398 | mRNA splicing, via spliceosome | 37/877 | 344/17913 | 0.0000 | 0.0002 | 37 |
| GO:0070663 | regulation of leukocyte proliferation | 27/877 | 214/17913 | 0.0000 | 0.0002 | 27 |
| GO:0050708 | regulation of protein secretion | 45/877 | 456/17913 | 0.0000 | 0.0002 | 45 |
| GO:0044106 | cellular amine metabolic process | 19/877 | 121/17913 | 0.0000 | 0.0002 | 19 |
| GO:0060048 | cardiac muscle contraction | 20/877 | 132/17913 | 0.0000 | 0.0002 | 20 |
| GO:0090066 | regulation of anatomical structure size | 44/877 | 442/17913 | 0.0000 | 0.0002 | 44 |
| GO:0033238 | regulation of cellular amine metabolic process | 15/877 | 80/17913 | 0.0000 | 0.0002 | 15 |
| GO:0051090 | regulation of DNA-binding transcription factor activity | 43/877 | 429/17913 | 0.0000 | 0.0002 | 43 |
| GO:0003006 | developmental process involved in reproduction | 58/877 | 649/17913 | 0.0000 | 0.0002 | 58 |
| GO:0006816 | calcium ion transport | 42/877 | 415/17913 | 0.0000 | 0.0002 | 42 |
| GO:2000300 | regulation of synaptic vesicle exocytosis | 14/877 | 71/17913 | 0.0000 | 0.0002 | 14 |
| GO:0045597 | positive regulation of cell differentiation | 78/877 | 962/17913 | 0.0000 | 0.0002 | 78 |
| GO:0071496 | cellular response to external stimulus | 35/877 | 320/17913 | 0.0000 | 0.0002 | 35 |
| GO:0055117 | regulation of cardiac muscle contraction | 15/877 | 81/17913 | 0.0000 | 0.0002 | 15 |
| GO:0001656 | metanephros development | 16/877 | 91/17913 | 0.0000 | 0.0002 | 16 |
| GO:0050806 | positive regulation of synaptic transmission | 21/877 | 145/17913 | 0.0000 | 0.0002 | 21 |
| GO:0001817 | regulation of cytokine production | 61/877 | 698/17913 | 0.0000 | 0.0002 | 61 |
| GO:0050796 | regulation of insulin secretion | 23/877 | 169/17913 | 0.0000 | 0.0002 | 23 |
| GO:1905330 | regulation of morphogenesis of an epithelium | 24/877 | 181/17913 | 0.0000 | 0.0002 | 24 |
| GO:0043549 | regulation of kinase activity | 68/877 | 808/17913 | 0.0000 | 0.0002 | 68 |
| GO:0046651 | lymphocyte proliferation | 29/877 | 244/17913 | 0.0000 | 0.0002 | 29 |
| GO:0051924 | regulation of calcium ion transport | 29/877 | 244/17913 | 0.0000 | 0.0002 | 29 |
| GO:0070661 | leukocyte proliferation | 31/877 | 270/17913 | 0.0000 | 0.0002 | 31 |
| GO:0032409 | regulation of transporter activity | 30/877 | 257/17913 | 0.0000 | 0.0002 | 30 |
| GO:0031669 | cellular response to nutrient levels | 27/877 | 220/17913 | 0.0000 | 0.0002 | 27 |
| GO:0032943 | mononuclear cell proliferation | 29/877 | 246/17913 | 0.0000 | 0.0003 | 29 |
| GO:0016071 | mRNA metabolic process | 68/877 | 815/17913 | 0.0000 | 0.0003 | 68 |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 18/877 | 115/17913 | 0.0000 | 0.0003 | 18 |
| GO:0050900 | leukocyte migration | 45/877 | 467/17913 | 0.0000 | 0.0003 | 45 |
| GO:0042129 | regulation of T cell proliferation | 21/877 | 149/17913 | 0.0000 | 0.0003 | 21 |
| GO:1903706 | regulation of hemopoiesis | 45/877 | 468/17913 | 0.0000 | 0.0003 | 45 |
| GO:0032989 | cellular component morphogenesis | 77/877 | 960/17913 | 0.0000 | 0.0003 | 77 |
| GO:0006886 | intracellular protein transport | 69/877 | 833/17913 | 0.0000 | 0.0003 | 69 |
| GO:0007221 | positive regulation of transcription of Notch receptor target | 7/877 | 18/17913 | 0.0000 | 0.0003 | 7 |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 27/877 | 223/17913 | 0.0000 | 0.0003 | 27 |
| GO:0002764 | immune response-regulating signaling pathway | 54/877 | 603/17913 | 0.0000 | 0.0003 | 54 |
| GO:0010469 | regulation of signaling receptor activity | 53/877 | 588/17913 | 0.0000 | 0.0003 | 53 |
| GO:0060047 | heart contraction | 31/877 | 275/17913 | 0.0000 | 0.0003 | 31 |
| GO:0051100 | negative regulation of binding | 22/877 | 162/17913 | 0.0000 | 0.0003 | 22 |
| GO:0006913 | nucleocytoplasmic transport | 33/877 | 302/17913 | 0.0000 | 0.0003 | 33 |
| GO:0071322 | cellular response to carbohydrate stimulus | 20/877 | 139/17913 | 0.0000 | 0.0003 | 20 |
| GO:0098693 | regulation of synaptic vesicle cycle | 17/877 | 106/17913 | 0.0000 | 0.0003 | 17 |
| GO:0090257 | regulation of muscle system process | 29/877 | 251/17913 | 0.0000 | 0.0003 | 29 |
| GO:0017144 | drug metabolic process | 66/877 | 792/17913 | 0.0000 | 0.0003 | 66 |
| GO:0048013 | ephrin receptor signaling pathway | 15/877 | 86/17913 | 0.0000 | 0.0004 | 15 |
| GO:0051169 | nuclear transport | 33/877 | 305/17913 | 0.0000 | 0.0004 | 33 |
| GO:0045785 | positive regulation of cell adhesion | 39/877 | 388/17913 | 0.0000 | 0.0004 | 39 |
| GO:0048589 | developmental growth | 55/877 | 624/17913 | 0.0000 | 0.0004 | 55 |
| GO:0042098 | T cell proliferation | 23/877 | 177/17913 | 0.0000 | 0.0004 | 23 |
| GO:0046683 | response to organophosphorus | 19/877 | 130/17913 | 0.0000 | 0.0004 | 19 |
| GO:0045859 | regulation of protein kinase activity | 62/877 | 733/17913 | 0.0000 | 0.0004 | 62 |
| GO:0060284 | regulation of cell development | 72/877 | 893/17913 | 0.0000 | 0.0004 | 72 |
| GO:0048872 | homeostasis of number of cells | 28/877 | 241/17913 | 0.0000 | 0.0004 | 28 |
| GO:0002757 | immune response-activating signal transduction | 51/877 | 567/17913 | 0.0000 | 0.0004 | 51 |
| GO:0098662 | inorganic cation transmembrane transport | 56/877 | 643/17913 | 0.0000 | 0.0004 | 56 |
| GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 17/877 | 109/17913 | 0.0000 | 0.0004 | 17 |
| GO:0030163 | protein catabolic process | 66/877 | 799/17913 | 0.0000 | 0.0004 | 66 |
| GO:0009314 | response to radiation | 42/877 | 435/17913 | 0.0000 | 0.0004 | 42 |
| GO:0007548 | sex differentiation | 30/877 | 269/17913 | 0.0000 | 0.0005 | 30 |
| GO:0030258 | lipid modification | 24/877 | 192/17913 | 0.0000 | 0.0005 | 24 |
| GO:0040017 | positive regulation of locomotion | 51/877 | 570/17913 | 0.0000 | 0.0005 | 51 |
| GO:1903169 | regulation of calcium ion transmembrane transport | 20/877 | 144/17913 | 0.0000 | 0.0005 | 20 |
| GO:2000147 | positive regulation of cell motility | 49/877 | 540/17913 | 0.0000 | 0.0005 | 49 |
| GO:0051272 | positive regulation of cellular component movement | 50/877 | 555/17913 | 0.0000 | 0.0005 | 50 |
| GO:0050852 | T cell receptor signaling pathway | 23/877 | 180/17913 | 0.0000 | 0.0005 | 23 |
| GO:0006352 | DNA-templated transcription, initiation | 27/877 | 231/17913 | 0.0000 | 0.0005 | 27 |
| GO:0034612 | response to tumor necrosis factor | 31/877 | 284/17913 | 0.0000 | 0.0005 | 31 |
| GO:0043401 | steroid hormone mediated signaling pathway | 23/877 | 181/17913 | 0.0000 | 0.0005 | 23 |
| GO:0051099 | positive regulation of binding | 23/877 | 181/17913 | 0.0000 | 0.0005 | 23 |
| GO:0046822 | regulation of nucleocytoplasmic transport | 16/877 | 100/17913 | 0.0000 | 0.0005 | 16 |
| GO:0018149 | peptide cross-linking | 9/877 | 34/17913 | 0.0000 | 0.0005 | 9 |
| GO:0030522 | intracellular receptor signaling pathway | 30/877 | 272/17913 | 0.0000 | 0.0006 | 30 |
| GO:0008380 | RNA splicing | 42/877 | 440/17913 | 0.0000 | 0.0006 | 42 |
| GO:0071560 | cellular response to transforming growth factor beta stimulus | 27/877 | 233/17913 | 0.0000 | 0.0006 | 27 |
| GO:0002026 | regulation of the force of heart contraction | 8/877 | 27/17913 | 0.0000 | 0.0006 | 8 |
| GO:0072207 | metanephric epithelium development | 8/877 | 27/17913 | 0.0000 | 0.0006 | 8 |
| GO:0070555 | response to interleukin-1 | 23/877 | 183/17913 | 0.0000 | 0.0006 | 23 |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity | 22/877 | 171/17913 | 0.0000 | 0.0006 | 22 |
| GO:1903311 | regulation of mRNA metabolic process | 30/877 | 275/17913 | 0.0000 | 0.0007 | 30 |
| GO:0033555 | multicellular organismal response to stress | 13/877 | 71/17913 | 0.0000 | 0.0007 | 13 |
| GO:0051952 | regulation of amine transport | 13/877 | 71/17913 | 0.0000 | 0.0007 | 13 |
| GO:0045664 | regulation of neuron differentiation | 53/877 | 609/17913 | 0.0000 | 0.0007 | 53 |
| GO:0051480 | regulation of cytosolic calcium ion concentration | 31/877 | 289/17913 | 0.0000 | 0.0007 | 31 |
| GO:0032526 | response to retinoic acid | 16/877 | 103/17913 | 0.0000 | 0.0007 | 16 |
| GO:0048857 | neural nucleus development | 12/877 | 62/17913 | 0.0000 | 0.0007 | 12 |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 52/877 | 596/17913 | 0.0000 | 0.0007 | 52 |
| GO:0019932 | second-messenger-mediated signaling | 36/877 | 360/17913 | 0.0000 | 0.0007 | 36 |
| GO:1902036 | regulation of hematopoietic stem cell differentiation | 13/877 | 72/17913 | 0.0000 | 0.0008 | 13 |
| GO:0030155 | regulation of cell adhesion | 56/877 | 659/17913 | 0.0000 | 0.0008 | 56 |
| GO:0002696 | positive regulation of leukocyte activation | 32/877 | 305/17913 | 0.0000 | 0.0008 | 32 |
| GO:0022409 | positive regulation of cell-cell adhesion | 28/877 | 251/17913 | 0.0000 | 0.0008 | 28 |
| GO:0031668 | cellular response to extracellular stimulus | 28/877 | 251/17913 | 0.0000 | 0.0008 | 28 |
| GO:0051591 | response to cAMP | 15/877 | 93/17913 | 0.0000 | 0.0008 | 15 |
| GO:0030879 | mammary gland development | 19/877 | 138/17913 | 0.0000 | 0.0008 | 19 |
| GO:0070252 | actin-mediated cell contraction | 17/877 | 115/17913 | 0.0000 | 0.0008 | 17 |
| GO:0044706 | multi-multicellular organism process | 26/877 | 225/17913 | 0.0000 | 0.0008 | 26 |
| GO:0099504 | synaptic vesicle cycle | 21/877 | 162/17913 | 0.0000 | 0.0008 | 21 |
| GO:0017157 | regulation of exocytosis | 23/877 | 187/17913 | 0.0000 | 0.0008 | 23 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 41/877 | 434/17913 | 0.0000 | 0.0008 | 41 |
| GO:0046649 | lymphocyte activation | 54/877 | 630/17913 | 0.0000 | 0.0008 | 54 |
| GO:0060218 | hematopoietic stem cell differentiation | 14/877 | 83/17913 | 0.0000 | 0.0008 | 14 |
| GO:0060078 | regulation of postsynaptic membrane potential | 18/877 | 127/17913 | 0.0000 | 0.0008 | 18 |
| GO:0071559 | response to transforming growth factor beta | 27/877 | 239/17913 | 0.0000 | 0.0008 | 27 |
| GO:0050727 | regulation of inflammatory response | 44/877 | 479/17913 | 0.0000 | 0.0008 | 44 |
| GO:0071356 | cellular response to tumor necrosis factor | 29/877 | 266/17913 | 0.0000 | 0.0008 | 29 |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 20/877 | 151/17913 | 0.0000 | 0.0008 | 20 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 25/877 | 214/17913 | 0.0001 | 0.0009 | 25 |
| GO:0051168 | nuclear export | 22/877 | 176/17913 | 0.0001 | 0.0009 | 22 |
| GO:0007599 | hemostasis | 34/877 | 336/17913 | 0.0001 | 0.0009 | 34 |
| GO:0051338 | regulation of transferase activity | 71/877 | 903/17913 | 0.0001 | 0.0009 | 71 |
| GO:0051707 | response to other organism | 71/877 | 903/17913 | 0.0001 | 0.0009 | 71 |
| GO:1901019 | regulation of calcium ion transmembrane transporter activity | 14/877 | 84/17913 | 0.0001 | 0.0009 | 14 |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 31/877 | 295/17913 | 0.0001 | 0.0009 | 31 |
| GO:0043207 | response to external biotic stimulus | 71/877 | 905/17913 | 0.0001 | 0.0009 | 71 |
| GO:0051590 | positive regulation of neurotransmitter transport | 9/877 | 37/17913 | 0.0001 | 0.0009 | 9 |
| GO:0080135 | regulation of cellular response to stress | 59/877 | 713/17913 | 0.0001 | 0.0009 | 59 |
| GO:0010720 | positive regulation of cell development | 47/877 | 528/17913 | 0.0001 | 0.0010 | 47 |
| GO:0072593 | reactive oxygen species metabolic process | 29/877 | 269/17913 | 0.0001 | 0.0010 | 29 |
| GO:0032388 | positive regulation of intracellular transport | 24/877 | 203/17913 | 0.0001 | 0.0010 | 24 |
| GO:0045766 | positive regulation of angiogenesis | 24/877 | 203/17913 | 0.0001 | 0.0010 | 24 |
| GO:0006397 | mRNA processing | 45/877 | 499/17913 | 0.0001 | 0.0010 | 45 |
| GO:0043410 | positive regulation of MAPK cascade | 45/877 | 499/17913 | 0.0001 | 0.0010 | 45 |
| GO:0010332 | response to gamma radiation | 11/877 | 55/17913 | 0.0001 | 0.0010 | 11 |
| GO:0006367 | transcription initiation from RNA polymerase II promoter | 22/877 | 178/17913 | 0.0001 | 0.0010 | 22 |
| GO:0040008 | regulation of growth | 56/877 | 668/17913 | 0.0001 | 0.0010 | 56 |
| GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 14/877 | 85/17913 | 0.0001 | 0.0010 | 14 |
| GO:0033002 | muscle cell proliferation | 27/877 | 243/17913 | 0.0001 | 0.0010 | 27 |
| GO:0046928 | regulation of neurotransmitter secretion | 15/877 | 96/17913 | 0.0001 | 0.0010 | 15 |
| GO:0008361 | regulation of cell size | 20/877 | 154/17913 | 0.0001 | 0.0010 | 20 |
| GO:0071300 | cellular response to retinoic acid | 12/877 | 65/17913 | 0.0001 | 0.0010 | 12 |
| GO:0001678 | cellular glucose homeostasis | 19/877 | 142/17913 | 0.0001 | 0.0010 | 19 |
| GO:1901796 | regulation of signal transduction by p53 class mediator | 22/877 | 179/17913 | 0.0001 | 0.0011 | 22 |
| GO:0045926 | negative regulation of growth | 27/877 | 244/17913 | 0.0001 | 0.0011 | 27 |
| GO:0051051 | negative regulation of transport | 45/877 | 502/17913 | 0.0001 | 0.0011 | 45 |
| GO:0051251 | positive regulation of lymphocyte activation | 28/877 | 258/17913 | 0.0001 | 0.0011 | 28 |
| GO:0071326 | cellular response to monosaccharide stimulus | 18/877 | 131/17913 | 0.0001 | 0.0011 | 18 |
| GO:0031960 | response to corticosteroid | 20/877 | 155/17913 | 0.0001 | 0.0011 | 20 |
| GO:0002429 | immune response-activating cell surface receptor signaling pathway | 38/877 | 399/17913 | 0.0001 | 0.0011 | 38 |
| GO:0097305 | response to alcohol | 26/877 | 232/17913 | 0.0001 | 0.0012 | 26 |
| GO:0007565 | female pregnancy | 23/877 | 193/17913 | 0.0001 | 0.0012 | 23 |
| GO:0015837 | amine transport | 13/877 | 76/17913 | 0.0001 | 0.0012 | 13 |
| GO:0050767 | regulation of neurogenesis | 62/877 | 768/17913 | 0.0001 | 0.0012 | 62 |
| GO:0051129 | negative regulation of cellular component organization | 56/877 | 673/17913 | 0.0001 | 0.0012 | 56 |
| GO:0071347 | cellular response to interleukin-1 | 20/877 | 156/17913 | 0.0001 | 0.0012 | 20 |
| GO:0051249 | regulation of lymphocyte activation | 38/877 | 401/17913 | 0.0001 | 0.0012 | 38 |
| GO:0072215 | regulation of metanephros development | 7/877 | 23/17913 | 0.0001 | 0.0013 | 7 |
| GO:0072243 | metanephric nephron epithelium development | 7/877 | 23/17913 | 0.0001 | 0.0013 | 7 |
| GO:0001819 | positive regulation of cytokine production | 41/877 | 446/17913 | 0.0001 | 0.0013 | 41 |
| GO:0032412 | regulation of ion transmembrane transporter activity | 26/877 | 234/17913 | 0.0001 | 0.0013 | 26 |
| GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 11/877 | 57/17913 | 0.0001 | 0.0013 | 11 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 13/877 | 77/17913 | 0.0001 | 0.0013 | 13 |
| GO:0014074 | response to purine-containing compound | 19/877 | 145/17913 | 0.0001 | 0.0013 | 19 |
| GO:0035567 | non-canonical Wnt signaling pathway | 19/877 | 145/17913 | 0.0001 | 0.0013 | 19 |
| GO:0001503 | ossification | 37/877 | 388/17913 | 0.0001 | 0.0013 | 37 |
| GO:0001504 | neurotransmitter uptake | 9/877 | 39/17913 | 0.0001 | 0.0013 | 9 |
| GO:0007596 | blood coagulation | 33/877 | 331/17913 | 0.0001 | 0.0013 | 33 |
| GO:0009790 | embryo development | 74/877 | 968/17913 | 0.0001 | 0.0013 | 74 |
| GO:0031103 | axon regeneration | 10/877 | 48/17913 | 0.0001 | 0.0014 | 10 |
| GO:0022407 | regulation of cell-cell adhesion | 37/877 | 389/17913 | 0.0001 | 0.0014 | 37 |
| GO:0030100 | regulation of endocytosis | 28/877 | 262/17913 | 0.0001 | 0.0014 | 28 |
| GO:0043488 | regulation of mRNA stability | 20/877 | 158/17913 | 0.0001 | 0.0014 | 20 |
| GO:0050867 | positive regulation of cell activation | 32/877 | 319/17913 | 0.0001 | 0.0015 | 32 |
| GO:0046007 | negative regulation of activated T cell proliferation | 5/877 | 11/17913 | 0.0001 | 0.0015 | 5 |
| GO:0050805 | negative regulation of synaptic transmission | 12/877 | 68/17913 | 0.0001 | 0.0015 | 12 |
| GO:0016079 | synaptic vesicle exocytosis | 15/877 | 100/17913 | 0.0001 | 0.0015 | 15 |
| GO:0001508 | action potential | 17/877 | 123/17913 | 0.0001 | 0.0015 | 17 |
| GO:0015980 | energy derivation by oxidation of organic compounds | 28/877 | 264/17913 | 0.0001 | 0.0015 | 28 |
| GO:0048660 | regulation of smooth muscle cell proliferation | 21/877 | 172/17913 | 0.0001 | 0.0015 | 21 |
| GO:0050870 | positive regulation of T cell activation | 23/877 | 198/17913 | 0.0001 | 0.0016 | 23 |
| GO:1902600 | proton transmembrane transport | 19/877 | 148/17913 | 0.0001 | 0.0017 | 19 |
| GO:1903305 | regulation of regulated secretory pathway | 18/877 | 136/17913 | 0.0001 | 0.0017 | 18 |
| GO:0071295 | cellular response to vitamin | 8/877 | 32/17913 | 0.0001 | 0.0017 | 8 |
| GO:0050817 | coagulation | 33/877 | 337/17913 | 0.0001 | 0.0018 | 33 |
| GO:0007269 | neurotransmitter secretion | 19/877 | 149/17913 | 0.0001 | 0.0018 | 19 |
| GO:0048659 | smooth muscle cell proliferation | 21/877 | 174/17913 | 0.0001 | 0.0018 | 21 |
| GO:0050673 | epithelial cell proliferation | 39/877 | 425/17913 | 0.0001 | 0.0018 | 39 |
| GO:1901342 | regulation of vasculature development | 39/877 | 425/17913 | 0.0001 | 0.0018 | 39 |
| GO:0017158 | regulation of calcium ion-dependent exocytosis | 14/877 | 91/17913 | 0.0001 | 0.0019 | 14 |
| GO:0030335 | positive regulation of cell migration | 45/877 | 516/17913 | 0.0001 | 0.0019 | 45 |
| GO:0099643 | signal release from synapse | 19/877 | 150/17913 | 0.0001 | 0.0019 | 19 |
| GO:0007623 | circadian rhythm | 23/877 | 201/17913 | 0.0001 | 0.0019 | 23 |
| GO:0002260 | lymphocyte homeostasis | 11/877 | 60/17913 | 0.0001 | 0.0019 | 11 |
| GO:0006091 | generation of precursor metabolites and energy | 44/877 | 502/17913 | 0.0001 | 0.0020 | 44 |
| GO:0045765 | regulation of angiogenesis | 36/877 | 383/17913 | 0.0001 | 0.0020 | 36 |
| GO:0006611 | protein export from nucleus | 20/877 | 163/17913 | 0.0001 | 0.0020 | 20 |
| GO:0043487 | regulation of RNA stability | 20/877 | 163/17913 | 0.0001 | 0.0020 | 20 |
| GO:0099565 | chemical synaptic transmission, postsynaptic | 15/877 | 103/17913 | 0.0001 | 0.0020 | 15 |
| GO:0015696 | ammonium transport | 13/877 | 81/17913 | 0.0001 | 0.0020 | 13 |
| GO:0007584 | response to nutrient | 24/877 | 215/17913 | 0.0001 | 0.0020 | 24 |
| GO:0060249 | anatomical structure homeostasis | 38/877 | 413/17913 | 0.0001 | 0.0020 | 38 |
| GO:0019884 | antigen processing and presentation of exogenous antigen | 21/877 | 176/17913 | 0.0001 | 0.0020 | 21 |
| GO:0050678 | regulation of epithelial cell proliferation | 35/877 | 369/17913 | 0.0001 | 0.0020 | 35 |
| GO:0042110 | T cell activation | 40/877 | 443/17913 | 0.0001 | 0.0020 | 40 |
| GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator | 8/877 | 33/17913 | 0.0001 | 0.0020 | 8 |
| GO:0051954 | positive regulation of amine transport | 8/877 | 33/17913 | 0.0001 | 0.0020 | 8 |
| GO:0050714 | positive regulation of protein secretion | 27/877 | 256/17913 | 0.0002 | 0.0021 | 27 |
| GO:0097094 | craniofacial suture morphogenesis | 6/877 | 18/17913 | 0.0002 | 0.0021 | 6 |
| GO:0051384 | response to glucocorticoid | 18/877 | 139/17913 | 0.0002 | 0.0021 | 18 |
| GO:0017156 | calcium ion regulated exocytosis | 17/877 | 127/17913 | 0.0002 | 0.0021 | 17 |
| GO:0051960 | regulation of nervous system development | 67/877 | 870/17913 | 0.0002 | 0.0021 | 67 |
| GO:0071383 | cellular response to steroid hormone stimulus | 26/877 | 243/17913 | 0.0002 | 0.0021 | 26 |
| GO:0006521 | regulation of cellular amino acid metabolic process | 11/877 | 61/17913 | 0.0002 | 0.0022 | 11 |
| GO:0019395 | fatty acid oxidation | 14/877 | 93/17913 | 0.0002 | 0.0022 | 14 |
| GO:0009607 | response to biotic stimulus | 71/877 | 938/17913 | 0.0002 | 0.0022 | 71 |
| GO:0032355 | response to estradiol | 17/877 | 128/17913 | 0.0002 | 0.0023 | 17 |
| GO:0071333 | cellular response to glucose stimulus | 17/877 | 128/17913 | 0.0002 | 0.0023 | 17 |
| GO:0060485 | mesenchyme development | 27/877 | 258/17913 | 0.0002 | 0.0023 | 27 |
| GO:0044257 | cellular protein catabolic process | 53/877 | 648/17913 | 0.0002 | 0.0024 | 53 |
| GO:0034605 | cellular response to heat | 16/877 | 117/17913 | 0.0002 | 0.0024 | 16 |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 14/877 | 94/17913 | 0.0002 | 0.0024 | 14 |
| GO:0035265 | organ growth | 21/877 | 179/17913 | 0.0002 | 0.0024 | 21 |
| GO:1901385 | regulation of voltage-gated calcium channel activity | 8/877 | 34/17913 | 0.0002 | 0.0024 | 8 |
| GO:1904018 | positive regulation of vasculature development | 25/877 | 232/17913 | 0.0002 | 0.0024 | 25 |
| GO:1903827 | regulation of cellular protein localization | 44/877 | 509/17913 | 0.0002 | 0.0025 | 44 |
| GO:0030162 | regulation of proteolysis | 60/877 | 762/17913 | 0.0002 | 0.0025 | 60 |
| GO:0071377 | cellular response to glucagon stimulus | 7/877 | 26/17913 | 0.0002 | 0.0025 | 7 |
| GO:0072202 | cell differentiation involved in metanephros development | 7/877 | 26/17913 | 0.0002 | 0.0025 | 7 |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | 20/877 | 167/17913 | 0.0002 | 0.0026 | 20 |
| GO:0071331 | cellular response to hexose stimulus | 17/877 | 130/17913 | 0.0002 | 0.0026 | 17 |
| GO:0007589 | body fluid secretion | 14/877 | 95/17913 | 0.0002 | 0.0027 | 14 |
| GO:0034440 | lipid oxidation | 14/877 | 95/17913 | 0.0002 | 0.0027 | 14 |
| GO:0060079 | excitatory postsynaptic potential | 14/877 | 95/17913 | 0.0002 | 0.0027 | 14 |
| GO:2000696 | regulation of epithelial cell differentiation involved in kidney development | 6/877 | 19/17913 | 0.0002 | 0.0027 | 6 |
| GO:1903829 | positive regulation of cellular protein localization | 31/877 | 318/17913 | 0.0002 | 0.0027 | 31 |
| GO:0070997 | neuron death | 33/877 | 347/17913 | 0.0002 | 0.0027 | 33 |
| GO:0031099 | regeneration | 22/877 | 194/17913 | 0.0002 | 0.0028 | 22 |
| GO:1905475 | regulation of protein localization to membrane | 21/877 | 181/17913 | 0.0002 | 0.0028 | 21 |
| GO:0019933 | cAMP-mediated signaling | 18/877 | 143/17913 | 0.0002 | 0.0028 | 18 |
| GO:0010035 | response to inorganic substance | 45/877 | 528/17913 | 0.0002 | 0.0028 | 45 |
| GO:0048738 | cardiac muscle tissue development | 24/877 | 221/17913 | 0.0002 | 0.0028 | 24 |
| GO:0001906 | cell killing | 19/877 | 156/17913 | 0.0002 | 0.0029 | 19 |
| GO:0048167 | regulation of synaptic plasticity | 20/877 | 169/17913 | 0.0002 | 0.0029 | 20 |
| GO:0035850 | epithelial cell differentiation involved in kidney development | 9/877 | 44/17913 | 0.0002 | 0.0029 | 9 |
| GO:0030048 | actin filament-based movement | 17/877 | 132/17913 | 0.0002 | 0.0031 | 17 |
| GO:0060401 | cytosolic calcium ion transport | 19/877 | 157/17913 | 0.0002 | 0.0031 | 19 |
| GO:0062012 | regulation of small molecule metabolic process | 39/877 | 439/17913 | 0.0002 | 0.0031 | 39 |
| GO:0043254 | regulation of protein complex assembly | 37/877 | 409/17913 | 0.0002 | 0.0031 | 37 |
| GO:0043408 | regulation of MAPK cascade | 55/877 | 689/17913 | 0.0002 | 0.0031 | 55 |
| GO:0007610 | behavior | 48/877 | 578/17913 | 0.0003 | 0.0031 | 48 |
| GO:0097529 | myeloid leukocyte migration | 20/877 | 170/17913 | 0.0003 | 0.0031 | 20 |
| GO:0061005 | cell differentiation involved in kidney development | 10/877 | 54/17913 | 0.0003 | 0.0031 | 10 |
| GO:0050863 | regulation of T cell activation | 30/877 | 307/17913 | 0.0003 | 0.0031 | 30 |
| GO:0060123 | regulation of growth hormone secretion | 5/877 | 13/17913 | 0.0003 | 0.0031 | 5 |
| GO:0060452 | positive regulation of cardiac muscle contraction | 5/877 | 13/17913 | 0.0003 | 0.0031 | 5 |
| GO:0072182 | regulation of nephron tubule epithelial cell differentiation | 5/877 | 13/17913 | 0.0003 | 0.0031 | 5 |
| GO:1900272 | negative regulation of long-term synaptic potentiation | 5/877 | 13/17913 | 0.0003 | 0.0031 | 5 |
| GO:0050769 | positive regulation of neurogenesis | 40/877 | 455/17913 | 0.0003 | 0.0031 | 40 |
| GO:0031348 | negative regulation of defense response | 25/877 | 237/17913 | 0.0003 | 0.0032 | 25 |
| GO:0060402 | calcium ion transport into cytosol | 18/877 | 145/17913 | 0.0003 | 0.0032 | 18 |
| GO:0046777 | protein autophosphorylation | 23/877 | 210/17913 | 0.0003 | 0.0032 | 23 |
| GO:0002444 | myeloid leukocyte mediated immunity | 46/877 | 549/17913 | 0.0003 | 0.0033 | 46 |
| GO:0048598 | embryonic morphogenesis | 47/877 | 565/17913 | 0.0003 | 0.0034 | 47 |
| GO:0033762 | response to glucagon | 8/877 | 36/17913 | 0.0003 | 0.0034 | 8 |
| GO:0046825 | regulation of protein export from nucleus | 8/877 | 36/17913 | 0.0003 | 0.0034 | 8 |
| GO:0014823 | response to activity | 11/877 | 65/17913 | 0.0003 | 0.0034 | 11 |
| GO:0002027 | regulation of heart rate | 14/877 | 98/17913 | 0.0003 | 0.0035 | 14 |
| GO:0050865 | regulation of cell activation | 45/877 | 535/17913 | 0.0003 | 0.0035 | 45 |
| GO:0010975 | regulation of neuron projection development | 40/877 | 458/17913 | 0.0003 | 0.0035 | 40 |
| GO:0031102 | neuron projection regeneration | 10/877 | 55/17913 | 0.0003 | 0.0035 | 10 |
| GO:0032615 | interleukin-12 production | 10/877 | 55/17913 | 0.0003 | 0.0035 | 10 |
| GO:0098586 | cellular response to virus | 10/877 | 55/17913 | 0.0003 | 0.0035 | 10 |
| GO:0051650 | establishment of vesicle localization | 26/877 | 253/17913 | 0.0003 | 0.0035 | 26 |
| GO:0035270 | endocrine system development | 16/877 | 122/17913 | 0.0003 | 0.0035 | 16 |
| GO:0048638 | regulation of developmental growth | 31/877 | 325/17913 | 0.0003 | 0.0037 | 31 |
| GO:0003180 | aortic valve morphogenesis | 7/877 | 28/17913 | 0.0003 | 0.0037 | 7 |
| GO:0060292 | long-term synaptic depression | 7/877 | 28/17913 | 0.0003 | 0.0037 | 7 |
| GO:0045666 | positive regulation of neuron differentiation | 33/877 | 355/17913 | 0.0003 | 0.0038 | 33 |
| GO:0006635 | fatty acid beta-oxidation | 11/877 | 66/17913 | 0.0003 | 0.0038 | 11 |
| GO:0015844 | monoamine transport | 11/877 | 66/17913 | 0.0003 | 0.0038 | 11 |
| GO:0001736 | establishment of planar polarity | 16/877 | 123/17913 | 0.0003 | 0.0038 | 16 |
| GO:0007164 | establishment of tissue polarity | 16/877 | 123/17913 | 0.0003 | 0.0038 | 16 |
| GO:0002694 | regulation of leukocyte activation | 42/877 | 492/17913 | 0.0003 | 0.0039 | 42 |
| GO:0003018 | vascular process in circulatory system | 19/877 | 161/17913 | 0.0003 | 0.0040 | 19 |
| GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 20/877 | 174/17913 | 0.0003 | 0.0040 | 20 |
| GO:0001755 | neural crest cell migration | 8/877 | 37/17913 | 0.0003 | 0.0040 | 8 |
| GO:0051648 | vesicle localization | 27/877 | 270/17913 | 0.0004 | 0.0041 | 27 |
| GO:1901214 | regulation of neuron death | 30/877 | 313/17913 | 0.0004 | 0.0041 | 30 |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 14/877 | 100/17913 | 0.0004 | 0.0041 | 14 |
| GO:0043062 | extracellular structure organization | 35/877 | 387/17913 | 0.0004 | 0.0042 | 35 |
| GO:0048002 | antigen processing and presentation of peptide antigen | 21/877 | 188/17913 | 0.0004 | 0.0042 | 21 |
| GO:0070268 | cornification | 15/877 | 112/17913 | 0.0004 | 0.0042 | 15 |
| GO:0010506 | regulation of autophagy | 30/877 | 314/17913 | 0.0004 | 0.0043 | 30 |
| GO:0007517 | muscle organ development | 36/877 | 403/17913 | 0.0004 | 0.0043 | 36 |
| GO:0016042 | lipid catabolic process | 29/877 | 300/17913 | 0.0004 | 0.0044 | 29 |
| GO:0002275 | myeloid cell activation involved in immune response | 45/877 | 542/17913 | 0.0004 | 0.0044 | 45 |
| GO:0048588 | developmental cell growth | 23/877 | 216/17913 | 0.0004 | 0.0044 | 23 |
| GO:0050671 | positive regulation of lymphocyte proliferation | 16/877 | 125/17913 | 0.0004 | 0.0045 | 16 |
| GO:0048675 | axon extension | 14/877 | 101/17913 | 0.0004 | 0.0045 | 14 |
| GO:0032535 | regulation of cellular component size | 30/877 | 315/17913 | 0.0004 | 0.0045 | 30 |
| GO:0045333 | cellular respiration | 20/877 | 176/17913 | 0.0004 | 0.0045 | 20 |
| GO:0016572 | histone phosphorylation | 8/877 | 38/17913 | 0.0004 | 0.0047 | 8 |
| GO:0030901 | midbrain development | 13/877 | 90/17913 | 0.0004 | 0.0047 | 13 |
| GO:0002683 | negative regulation of immune system process | 39/877 | 451/17913 | 0.0004 | 0.0047 | 39 |
| GO:0009161 | ribonucleoside monophosphate metabolic process | 31/877 | 331/17913 | 0.0004 | 0.0047 | 31 |
| GO:0030856 | regulation of epithelial cell differentiation | 18/877 | 151/17913 | 0.0004 | 0.0048 | 18 |
| GO:0032024 | positive regulation of insulin secretion | 11/877 | 68/17913 | 0.0004 | 0.0048 | 11 |
| GO:1903524 | positive regulation of blood circulation | 11/877 | 68/17913 | 0.0004 | 0.0048 | 11 |
| GO:0032946 | positive regulation of mononuclear cell proliferation | 16/877 | 126/17913 | 0.0004 | 0.0048 | 16 |
| GO:0097006 | regulation of plasma lipoprotein particle levels | 14/877 | 102/17913 | 0.0004 | 0.0048 | 14 |
| GO:0009167 | purine ribonucleoside monophosphate metabolic process | 30/877 | 317/17913 | 0.0004 | 0.0048 | 30 |
| GO:0032147 | activation of protein kinase activity | 29/877 | 303/17913 | 0.0005 | 0.0050 | 29 |
| GO:0007369 | gastrulation | 20/877 | 178/17913 | 0.0005 | 0.0050 | 20 |
| GO:0061013 | regulation of mRNA catabolic process | 20/877 | 178/17913 | 0.0005 | 0.0050 | 20 |
| GO:0061138 | morphogenesis of a branching epithelium | 20/877 | 178/17913 | 0.0005 | 0.0050 | 20 |
| GO:0034767 | positive regulation of ion transmembrane transport | 18/877 | 152/17913 | 0.0005 | 0.0051 | 18 |
| GO:0009126 | purine nucleoside monophosphate metabolic process | 30/877 | 318/17913 | 0.0005 | 0.0051 | 30 |
| GO:0043299 | leukocyte degranulation | 44/877 | 532/17913 | 0.0005 | 0.0053 | 44 |
| GO:2001023 | regulation of response to drug | 12/877 | 80/17913 | 0.0005 | 0.0053 | 12 |
| GO:0072073 | kidney epithelium development | 17/877 | 140/17913 | 0.0005 | 0.0053 | 17 |
| GO:1904064 | positive regulation of cation transmembrane transport | 17/877 | 140/17913 | 0.0005 | 0.0053 | 17 |
| GO:1902991 | regulation of amyloid precursor protein catabolic process | 7/877 | 30/17913 | 0.0005 | 0.0053 | 7 |
| GO:0006974 | cellular response to DNA damage stimulus | 60/877 | 791/17913 | 0.0005 | 0.0054 | 60 |
| GO:0019935 | cyclic-nucleotide-mediated signaling | 19/877 | 166/17913 | 0.0005 | 0.0054 | 19 |
| GO:0045823 | positive regulation of heart contraction | 8/877 | 39/17913 | 0.0005 | 0.0054 | 8 |
| GO:0019882 | antigen processing and presentation | 23/877 | 220/17913 | 0.0005 | 0.0054 | 23 |
| GO:0033157 | regulation of intracellular protein transport | 23/877 | 220/17913 | 0.0005 | 0.0054 | 23 |
| GO:0035637 | multicellular organismal signaling | 21/877 | 193/17913 | 0.0005 | 0.0055 | 21 |
| GO:0010038 | response to metal ion | 31/877 | 335/17913 | 0.0005 | 0.0056 | 31 |
| GO:2001022 | positive regulation of response to DNA damage stimulus | 13/877 | 92/17913 | 0.0005 | 0.0056 | 13 |
| GO:0031214 | biomineral tissue development | 18/877 | 154/17913 | 0.0005 | 0.0058 | 18 |
| GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator | 5/877 | 15/17913 | 0.0006 | 0.0058 | 5 |
| GO:0072160 | nephron tubule epithelial cell differentiation | 5/877 | 15/17913 | 0.0006 | 0.0058 | 5 |
| GO:0061061 | muscle structure development | 51/877 | 647/17913 | 0.0006 | 0.0058 | 51 |
| GO:0009416 | response to light stimulus | 29/877 | 307/17913 | 0.0006 | 0.0059 | 29 |
| GO:0030518 | intracellular steroid hormone receptor signaling pathway | 16/877 | 129/17913 | 0.0006 | 0.0059 | 16 |
| GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 30/877 | 323/17913 | 0.0006 | 0.0063 | 30 |
| GO:0009615 | response to virus | 30/877 | 323/17913 | 0.0006 | 0.0063 | 30 |
| GO:0042987 | amyloid precursor protein catabolic process | 8/877 | 40/17913 | 0.0006 | 0.0063 | 8 |
| GO:0050832 | defense response to fungus | 8/877 | 40/17913 | 0.0006 | 0.0063 | 8 |
| GO:0046824 | positive regulation of nucleocytoplasmic transport | 10/877 | 60/17913 | 0.0006 | 0.0063 | 10 |
| GO:0002443 | leukocyte mediated immunity | 61/877 | 814/17913 | 0.0006 | 0.0063 | 61 |
| GO:0099084 | postsynaptic specialization organization | 7/877 | 31/17913 | 0.0006 | 0.0063 | 7 |
| GO:1903708 | positive regulation of hemopoiesis | 20/877 | 182/17913 | 0.0006 | 0.0063 | 20 |
| GO:0031670 | cellular response to nutrient | 11/877 | 71/17913 | 0.0006 | 0.0065 | 11 |
| GO:0050771 | negative regulation of axonogenesis | 9/877 | 50/17913 | 0.0006 | 0.0065 | 9 |
| GO:0051966 | regulation of synaptic transmission, glutamatergic | 9/877 | 50/17913 | 0.0006 | 0.0065 | 9 |
| GO:0048640 | negative regulation of developmental growth | 13/877 | 94/17913 | 0.0006 | 0.0066 | 13 |
| GO:0043200 | response to amino acid | 14/877 | 106/17913 | 0.0007 | 0.0067 | 14 |
| GO:0055017 | cardiac muscle tissue growth | 14/877 | 106/17913 | 0.0007 | 0.0067 | 14 |
| GO:0045165 | cell fate commitment | 24/877 | 238/17913 | 0.0007 | 0.0067 | 24 |
| GO:0072170 | metanephric tubule development | 6/877 | 23/17913 | 0.0007 | 0.0068 | 6 |
| GO:2000637 | positive regulation of gene silencing by miRNA | 6/877 | 23/17913 | 0.0007 | 0.0068 | 6 |
| GO:0006119 | oxidative phosphorylation | 16/877 | 131/17913 | 0.0007 | 0.0068 | 16 |
| GO:0050728 | negative regulation of inflammatory response | 19/877 | 170/17913 | 0.0007 | 0.0068 | 19 |
| GO:0010212 | response to ionizing radiation | 17/877 | 144/17913 | 0.0007 | 0.0069 | 17 |
| GO:0034622 | cellular protein-containing complex assembly | 69/877 | 952/17913 | 0.0007 | 0.0069 | 69 |
| GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors | 12/877 | 83/17913 | 0.0007 | 0.0069 | 12 |
| GO:0051928 | positive regulation of calcium ion transport | 15/877 | 119/17913 | 0.0007 | 0.0070 | 15 |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | 20/877 | 184/17913 | 0.0007 | 0.0071 | 20 |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 14/877 | 107/17913 | 0.0007 | 0.0072 | 14 |
| GO:0009620 | response to fungus | 9/877 | 51/17913 | 0.0007 | 0.0074 | 9 |
| GO:2000677 | regulation of transcription regulatory region DNA binding | 9/877 | 51/17913 | 0.0007 | 0.0074 | 9 |
| GO:0010001 | glial cell differentiation | 22/877 | 212/17913 | 0.0007 | 0.0074 | 22 |
| GO:0002244 | hematopoietic progenitor cell differentiation | 18/877 | 158/17913 | 0.0007 | 0.0074 | 18 |
| GO:0002262 | myeloid cell homeostasis | 17/877 | 145/17913 | 0.0007 | 0.0074 | 17 |
| GO:0003176 | aortic valve development | 7/877 | 32/17913 | 0.0008 | 0.0074 | 7 |
| GO:0007190 | activation of adenylate cyclase activity | 7/877 | 32/17913 | 0.0008 | 0.0074 | 7 |
| GO:0033028 | myeloid cell apoptotic process | 7/877 | 32/17913 | 0.0008 | 0.0074 | 7 |
| GO:0046688 | response to copper ion | 7/877 | 32/17913 | 0.0008 | 0.0074 | 7 |
| GO:0060562 | epithelial tube morphogenesis | 29/877 | 313/17913 | 0.0008 | 0.0075 | 29 |
| GO:0006163 | purine nucleotide metabolic process | 43/877 | 528/17913 | 0.0008 | 0.0075 | 43 |
| GO:0001776 | leukocyte homeostasis | 12/877 | 84/17913 | 0.0008 | 0.0075 | 12 |
| GO:0090559 | regulation of membrane permeability | 12/877 | 84/17913 | 0.0008 | 0.0075 | 12 |
| GO:0030252 | growth hormone secretion | 5/877 | 16/17913 | 0.0008 | 0.0075 | 5 |
| GO:0045989 | positive regulation of striated muscle contraction | 5/877 | 16/17913 | 0.0008 | 0.0075 | 5 |
| GO:0071871 | response to epinephrine | 5/877 | 16/17913 | 0.0008 | 0.0075 | 5 |
| GO:0007204 | positive regulation of cytosolic calcium ion concentration | 25/877 | 255/17913 | 0.0008 | 0.0075 | 25 |
| GO:0072521 | purine-containing compound metabolic process | 45/877 | 560/17913 | 0.0008 | 0.0075 | 45 |
| GO:0002064 | epithelial cell development | 21/877 | 199/17913 | 0.0008 | 0.0075 | 21 |
| GO:0048762 | mesenchymal cell differentiation | 21/877 | 199/17913 | 0.0008 | 0.0075 | 21 |
| GO:0032102 | negative regulation of response to external stimulus | 31/877 | 343/17913 | 0.0008 | 0.0075 | 31 |
| GO:0038093 | Fc receptor signaling pathway | 24/877 | 241/17913 | 0.0008 | 0.0076 | 24 |
| GO:0097191 | extrinsic apoptotic signaling pathway | 22/877 | 213/17913 | 0.0008 | 0.0076 | 22 |
| GO:0050880 | regulation of blood vessel size | 16/877 | 133/17913 | 0.0008 | 0.0076 | 16 |
| GO:0016049 | cell growth | 39/877 | 466/17913 | 0.0008 | 0.0077 | 39 |
| GO:0003208 | cardiac ventricle morphogenesis | 11/877 | 73/17913 | 0.0008 | 0.0077 | 11 |
| GO:0002685 | regulation of leukocyte migration | 20/877 | 186/17913 | 0.0008 | 0.0077 | 20 |
| GO:0010948 | negative regulation of cell cycle process | 31/877 | 344/17913 | 0.0008 | 0.0078 | 31 |
| GO:0002687 | positive regulation of leukocyte migration | 15/877 | 121/17913 | 0.0008 | 0.0080 | 15 |
| GO:0045596 | negative regulation of cell differentiation | 55/877 | 725/17913 | 0.0008 | 0.0081 | 55 |
| GO:0060148 | positive regulation of posttranscriptional gene silencing | 6/877 | 24/17913 | 0.0009 | 0.0081 | 6 |
| GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 12/877 | 85/17913 | 0.0009 | 0.0081 | 12 |
| GO:0035150 | regulation of tube size | 16/877 | 134/17913 | 0.0009 | 0.0081 | 16 |
| GO:0070665 | positive regulation of leukocyte proliferation | 16/877 | 134/17913 | 0.0009 | 0.0081 | 16 |
| GO:0019693 | ribose phosphate metabolic process | 43/877 | 531/17913 | 0.0009 | 0.0081 | 43 |
| GO:0090175 | regulation of establishment of planar polarity | 14/877 | 109/17913 | 0.0009 | 0.0081 | 14 |
| GO:0001909 | leukocyte mediated cytotoxicity | 13/877 | 97/17913 | 0.0009 | 0.0082 | 13 |
| GO:1902750 | negative regulation of cell cycle G2/M phase transition | 13/877 | 97/17913 | 0.0009 | 0.0082 | 13 |
| GO:0009150 | purine ribonucleotide metabolic process | 41/877 | 500/17913 | 0.0009 | 0.0083 | 41 |
| GO:0042594 | response to starvation | 19/877 | 174/17913 | 0.0009 | 0.0084 | 19 |
| GO:0007006 | mitochondrial membrane organization | 15/877 | 122/17913 | 0.0009 | 0.0085 | 15 |
| GO:0060537 | muscle tissue development | 34/877 | 392/17913 | 0.0009 | 0.0086 | 34 |
| GO:0050770 | regulation of axonogenesis | 17/877 | 148/17913 | 0.0009 | 0.0087 | 17 |
| GO:0035690 | cellular response to drug | 32/877 | 362/17913 | 0.0009 | 0.0087 | 32 |
| GO:0030432 | peristalsis | 4/877 | 10/17913 | 0.0009 | 0.0087 | 4 |
| GO:0071639 | positive regulation of monocyte chemotactic protein-1 production | 4/877 | 10/17913 | 0.0009 | 0.0087 | 4 |
| GO:0032602 | chemokine production | 12/877 | 86/17913 | 0.0010 | 0.0088 | 12 |
| GO:0009895 | negative regulation of catabolic process | 27/877 | 288/17913 | 0.0010 | 0.0089 | 27 |
| GO:0010522 | regulation of calcium ion transport into cytosol | 13/877 | 98/17913 | 0.0010 | 0.0089 | 13 |
| GO:0006914 | autophagy | 39/877 | 471/17913 | 0.0010 | 0.0090 | 39 |
| GO:0061919 | process utilizing autophagic mechanism | 39/877 | 471/17913 | 0.0010 | 0.0090 | 39 |
| GO:0032655 | regulation of interleukin-12 production | 9/877 | 53/17913 | 0.0010 | 0.0090 | 9 |
| GO:0042130 | negative regulation of T cell proliferation | 9/877 | 53/17913 | 0.0010 | 0.0090 | 9 |
| GO:0044242 | cellular lipid catabolic process | 20/877 | 189/17913 | 0.0010 | 0.0091 | 20 |
| GO:0032479 | regulation of type I interferon production | 15/877 | 123/17913 | 0.0010 | 0.0091 | 15 |
| GO:0021762 | substantia nigra development | 8/877 | 43/17913 | 0.0010 | 0.0091 | 8 |
| GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 8/877 | 43/17913 | 0.0010 | 0.0091 | 8 |
| GO:1904646 | cellular response to amyloid-beta | 8/877 | 43/17913 | 0.0010 | 0.0091 | 8 |
| GO:0035264 | multicellular organism growth | 17/877 | 149/17913 | 0.0010 | 0.0092 | 17 |
| GO:0010769 | regulation of cell morphogenesis involved in differentiation | 25/877 | 260/17913 | 0.0010 | 0.0093 | 25 |
| GO:0002283 | neutrophil activation involved in immune response | 40/877 | 488/17913 | 0.0010 | 0.0093 | 40 |
| GO:1905710 | positive regulation of membrane permeability | 10/877 | 64/17913 | 0.0010 | 0.0093 | 10 |
| GO:0009123 | nucleoside monophosphate metabolic process | 31/877 | 349/17913 | 0.0010 | 0.0093 | 31 |
| GO:0090185 | negative regulation of kidney development | 5/877 | 17/17913 | 0.0011 | 0.0094 | 5 |
| GO:0030099 | myeloid cell differentiation | 35/877 | 411/17913 | 0.0011 | 0.0096 | 35 |
| GO:0001963 | synaptic transmission, dopaminergic | 6/877 | 25/17913 | 0.0011 | 0.0096 | 6 |
| GO:0097435 | supramolecular fiber organization | 44/877 | 553/17913 | 0.0011 | 0.0096 | 44 |
| GO:0090316 | positive regulation of intracellular protein transport | 17/877 | 150/17913 | 0.0011 | 0.0097 | 17 |
| GO:0032735 | positive regulation of interleukin-12 production | 7/877 | 34/17913 | 0.0011 | 0.0099 | 7 |
| GO:0060428 | lung epithelium development | 7/877 | 34/17913 | 0.0011 | 0.0099 | 7 |
| GO:0002366 | leukocyte activation involved in immune response | 52/877 | 684/17913 | 0.0011 | 0.0099 | 52 |
| GO:0051937 | catecholamine transport | 9/877 | 54/17913 | 0.0011 | 0.0100 | 9 |
| GO:0070206 | protein trimerization | 9/877 | 54/17913 | 0.0011 | 0.0100 | 9 |
| GO:0099132 | ATP hydrolysis coupled cation transmembrane transport | 9/877 | 54/17913 | 0.0011 | 0.0100 | 9 |
| GO:1904645 | response to amyloid-beta | 9/877 | 54/17913 | 0.0011 | 0.0100 | 9 |
| GO:0030218 | erythrocyte differentiation | 14/877 | 112/17913 | 0.0011 | 0.0100 | 14 |
| GO:0060419 | heart growth | 14/877 | 112/17913 | 0.0011 | 0.0100 | 14 |
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0006259 | DNA metabolic process | 90/588 | 964/17913 | 0.0000 | 0.0000 | 90 |
| GO:0002366 | leukocyte activation involved in immune response | 73/588 | 684/17913 | 0.0000 | 0.0000 | 73 |
| GO:0002263 | cell activation involved in immune response | 73/588 | 688/17913 | 0.0000 | 0.0000 | 73 |
| GO:0000278 | mitotic cell cycle | 86/588 | 934/17913 | 0.0000 | 0.0000 | 86 |
| GO:0010948 | negative regulation of cell cycle process | 49/588 | 344/17913 | 0.0000 | 0.0000 | 49 |
| GO:1903047 | mitotic cell cycle process | 78/588 | 816/17913 | 0.0000 | 0.0000 | 78 |
| GO:0044419 | interspecies interaction between organisms | 84/588 | 928/17913 | 0.0000 | 0.0000 | 84 |
| GO:0044403 | symbiont process | 81/588 | 884/17913 | 0.0000 | 0.0000 | 81 |
| GO:0002443 | leukocyte mediated immunity | 77/588 | 814/17913 | 0.0000 | 0.0000 | 77 |
| GO:0016032 | viral process | 77/588 | 822/17913 | 0.0000 | 0.0000 | 77 |
| GO:0002274 | myeloid leukocyte activation | 67/588 | 652/17913 | 0.0000 | 0.0000 | 67 |
| GO:0036230 | granulocyte activation | 57/588 | 506/17913 | 0.0000 | 0.0000 | 57 |
| GO:0002275 | myeloid cell activation involved in immune response | 59/588 | 542/17913 | 0.0000 | 0.0000 | 59 |
| GO:0045055 | regulated exocytosis | 72/588 | 768/17913 | 0.0000 | 0.0000 | 72 |
| GO:0042119 | neutrophil activation | 56/588 | 499/17913 | 0.0000 | 0.0000 | 56 |
| GO:0043299 | leukocyte degranulation | 58/588 | 532/17913 | 0.0000 | 0.0000 | 58 |
| GO:0044772 | mitotic cell cycle phase transition | 60/588 | 565/17913 | 0.0000 | 0.0000 | 60 |
| GO:0002444 | myeloid leukocyte mediated immunity | 59/588 | 549/17913 | 0.0000 | 0.0000 | 59 |
| GO:0044770 | cell cycle phase transition | 62/588 | 609/17913 | 0.0000 | 0.0000 | 62 |
| GO:0002283 | neutrophil activation involved in immune response | 54/588 | 488/17913 | 0.0000 | 0.0000 | 54 |
| GO:0006887 | exocytosis | 75/588 | 862/17913 | 0.0000 | 0.0000 | 75 |
| GO:0043312 | neutrophil degranulation | 53/588 | 485/17913 | 0.0000 | 0.0000 | 53 |
| GO:0002446 | neutrophil mediated immunity | 53/588 | 499/17913 | 0.0000 | 0.0000 | 53 |
| GO:0010564 | regulation of cell cycle process | 68/588 | 764/17913 | 0.0000 | 0.0000 | 68 |
| GO:1903311 | regulation of mRNA metabolic process | 37/588 | 275/17913 | 0.0000 | 0.0000 | 37 |
| GO:1901991 | negative regulation of mitotic cell cycle phase transition | 34/588 | 235/17913 | 0.0000 | 0.0000 | 34 |
| GO:0045786 | negative regulation of cell cycle | 58/588 | 613/17913 | 0.0000 | 0.0000 | 58 |
| GO:0007346 | regulation of mitotic cell cycle | 58/588 | 622/17913 | 0.0000 | 0.0000 | 58 |
| GO:0002244 | hematopoietic progenitor cell differentiation | 27/588 | 158/17913 | 0.0000 | 0.0000 | 27 |
| GO:1901988 | negative regulation of cell cycle phase transition | 34/588 | 254/17913 | 0.0000 | 0.0000 | 34 |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 45/588 | 428/17913 | 0.0000 | 0.0000 | 45 |
| GO:0030097 | hemopoiesis | 68/588 | 847/17913 | 0.0000 | 0.0000 | 68 |
| GO:0045930 | negative regulation of mitotic cell cycle | 37/588 | 308/17913 | 0.0000 | 0.0000 | 37 |
| GO:0016071 | mRNA metabolic process | 66/588 | 815/17913 | 0.0000 | 0.0000 | 66 |
| GO:0045087 | innate immune response | 70/588 | 893/17913 | 0.0000 | 0.0000 | 70 |
| GO:0033044 | regulation of chromosome organization | 37/588 | 311/17913 | 0.0000 | 0.0000 | 37 |
| GO:0002520 | immune system development | 72/588 | 938/17913 | 0.0000 | 0.0000 | 72 |
| GO:0060218 | hematopoietic stem cell differentiation | 19/588 | 83/17913 | 0.0000 | 0.0000 | 19 |
| GO:1901987 | regulation of cell cycle phase transition | 46/588 | 464/17913 | 0.0000 | 0.0000 | 46 |
| GO:0048534 | hematopoietic or lymphoid organ development | 69/588 | 890/17913 | 0.0000 | 0.0000 | 69 |
| GO:0006260 | DNA replication | 33/588 | 260/17913 | 0.0000 | 0.0000 | 33 |
| GO:1902036 | regulation of hematopoietic stem cell differentiation | 17/588 | 72/17913 | 0.0000 | 0.0000 | 17 |
| GO:0019221 | cytokine-mediated signaling pathway | 61/588 | 764/17913 | 0.0000 | 0.0000 | 61 |
| GO:0033993 | response to lipid | 67/588 | 884/17913 | 0.0000 | 0.0000 | 67 |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 59/588 | 735/17913 | 0.0000 | 0.0000 | 59 |
| GO:0009607 | response to biotic stimulus | 69/588 | 938/17913 | 0.0000 | 0.0000 | 69 |
| GO:2001252 | positive regulation of chromosome organization | 25/588 | 169/17913 | 0.0000 | 0.0000 | 25 |
| GO:0070198 | protein localization to chromosome, telomeric region | 11/588 | 28/17913 | 0.0000 | 0.0000 | 11 |
| GO:1902749 | regulation of cell cycle G2/M phase transition | 27/588 | 202/17913 | 0.0000 | 0.0000 | 27 |
| GO:0070482 | response to oxygen levels | 39/588 | 389/17913 | 0.0000 | 0.0000 | 39 |
| GO:0000165 | MAPK cascade | 65/588 | 882/17913 | 0.0000 | 0.0000 | 65 |
| GO:0023014 | signal transduction by protein phosphorylation | 65/588 | 886/17913 | 0.0000 | 0.0000 | 65 |
| GO:2000736 | regulation of stem cell differentiation | 20/588 | 116/17913 | 0.0000 | 0.0000 | 20 |
| GO:0002521 | leukocyte differentiation | 44/588 | 485/17913 | 0.0000 | 0.0000 | 44 |
| GO:0006974 | cellular response to DNA damage stimulus | 60/588 | 791/17913 | 0.0000 | 0.0000 | 60 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 31/588 | 269/17913 | 0.0000 | 0.0000 | 31 |
| GO:0042493 | response to drug | 68/588 | 958/17913 | 0.0000 | 0.0000 | 68 |
| GO:0051052 | regulation of DNA metabolic process | 39/588 | 403/17913 | 0.0000 | 0.0000 | 39 |
| GO:0044839 | cell cycle G2/M phase transition | 30/588 | 257/17913 | 0.0000 | 0.0000 | 30 |
| GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 17/588 | 85/17913 | 0.0000 | 0.0000 | 17 |
| GO:0001666 | response to hypoxia | 36/588 | 354/17913 | 0.0000 | 0.0000 | 36 |
| GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 25/588 | 185/17913 | 0.0000 | 0.0000 | 25 |
| GO:0030162 | regulation of proteolysis | 58/588 | 762/17913 | 0.0000 | 0.0000 | 58 |
| GO:0044106 | cellular amine metabolic process | 20/588 | 121/17913 | 0.0000 | 0.0000 | 20 |
| GO:0019439 | aromatic compound catabolic process | 52/588 | 655/17913 | 0.0000 | 0.0000 | 52 |
| GO:0031329 | regulation of cellular catabolic process | 60/588 | 814/17913 | 0.0000 | 0.0000 | 60 |
| GO:0043487 | regulation of RNA stability | 23/588 | 163/17913 | 0.0000 | 0.0000 | 23 |
| GO:1903405 | protein localization to nuclear body | 7/588 | 10/17913 | 0.0000 | 0.0000 | 7 |
| GO:1904851 | positive regulation of establishment of protein localization to telomere | 7/588 | 10/17913 | 0.0000 | 0.0000 | 7 |
| GO:1904867 | protein localization to Cajal body | 7/588 | 10/17913 | 0.0000 | 0.0000 | 7 |
| GO:0036293 | response to decreased oxygen levels | 36/588 | 365/17913 | 0.0000 | 0.0000 | 36 |
| GO:0051054 | positive regulation of DNA metabolic process | 27/588 | 222/17913 | 0.0000 | 0.0000 | 27 |
| GO:0051707 | response to other organism | 64/588 | 903/17913 | 0.0000 | 0.0000 | 64 |
| GO:0006403 | RNA localization | 26/588 | 208/17913 | 0.0000 | 0.0000 | 26 |
| GO:0000086 | G2/M transition of mitotic cell cycle | 28/588 | 238/17913 | 0.0000 | 0.0000 | 28 |
| GO:0043207 | response to external biotic stimulus | 64/588 | 905/17913 | 0.0000 | 0.0000 | 64 |
| GO:0033238 | regulation of cellular amine metabolic process | 16/588 | 80/17913 | 0.0000 | 0.0000 | 16 |
| GO:0000723 | telomere maintenance | 22/588 | 154/17913 | 0.0000 | 0.0000 | 22 |
| GO:0009308 | amine metabolic process | 20/588 | 128/17913 | 0.0000 | 0.0000 | 20 |
| GO:0044843 | cell cycle G1/S phase transition | 31/588 | 288/17913 | 0.0000 | 0.0000 | 31 |
| GO:0034502 | protein localization to chromosome | 16/588 | 82/17913 | 0.0000 | 0.0000 | 16 |
| GO:0043488 | regulation of mRNA stability | 22/588 | 158/17913 | 0.0000 | 0.0000 | 22 |
| GO:0060249 | anatomical structure homeostasis | 38/588 | 413/17913 | 0.0000 | 0.0000 | 38 |
| GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 34/588 | 344/17913 | 0.0000 | 0.0000 | 34 |
| GO:0000398 | mRNA splicing, via spliceosome | 34/588 | 344/17913 | 0.0000 | 0.0000 | 34 |
| GO:0070203 | regulation of establishment of protein localization to telomere | 7/588 | 11/17913 | 0.0000 | 0.0000 | 7 |
| GO:0071103 | DNA conformation change | 30/588 | 279/17913 | 0.0000 | 0.0000 | 30 |
| GO:0050684 | regulation of mRNA processing | 18/588 | 108/17913 | 0.0000 | 0.0000 | 18 |
| GO:0046700 | heterocycle catabolic process | 50/588 | 641/17913 | 0.0000 | 0.0000 | 50 |
| GO:0044270 | cellular nitrogen compound catabolic process | 50/588 | 642/17913 | 0.0000 | 0.0000 | 50 |
| GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 16/588 | 85/17913 | 0.0000 | 0.0000 | 16 |
| GO:0000375 | RNA splicing, via transesterification reactions | 34/588 | 348/17913 | 0.0000 | 0.0000 | 34 |
| GO:0019882 | antigen processing and presentation | 26/588 | 220/17913 | 0.0000 | 0.0000 | 26 |
| GO:1901361 | organic cyclic compound catabolic process | 52/588 | 685/17913 | 0.0000 | 0.0000 | 52 |
| GO:0032392 | DNA geometric change | 16/588 | 86/17913 | 0.0000 | 0.0000 | 16 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 15/588 | 75/17913 | 0.0000 | 0.0000 | 15 |
| GO:0071897 | DNA biosynthetic process | 24/588 | 192/17913 | 0.0000 | 0.0000 | 24 |
| GO:0010638 | positive regulation of organelle organization | 47/588 | 591/17913 | 0.0000 | 0.0000 | 47 |
| GO:0046649 | lymphocyte activation | 49/588 | 630/17913 | 0.0000 | 0.0000 | 49 |
| GO:0017144 | drug metabolic process | 57/588 | 792/17913 | 0.0000 | 0.0000 | 57 |
| GO:2000573 | positive regulation of DNA biosynthetic process | 14/588 | 66/17913 | 0.0000 | 0.0000 | 14 |
| GO:0042110 | T cell activation | 39/588 | 443/17913 | 0.0000 | 0.0000 | 39 |
| GO:0006397 | mRNA processing | 42/588 | 499/17913 | 0.0000 | 0.0000 | 42 |
| GO:0051169 | nuclear transport | 31/588 | 305/17913 | 0.0000 | 0.0000 | 31 |
| GO:0070202 | regulation of establishment of protein localization to chromosome | 7/588 | 12/17913 | 0.0000 | 0.0000 | 7 |
| GO:1904816 | positive regulation of protein localization to chromosome, telomeric region | 7/588 | 12/17913 | 0.0000 | 0.0000 | 7 |
| GO:1990173 | protein localization to nucleoplasm | 7/588 | 12/17913 | 0.0000 | 0.0000 | 7 |
| GO:0034655 | nucleobase-containing compound catabolic process | 47/588 | 598/17913 | 0.0000 | 0.0000 | 47 |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 15/588 | 78/17913 | 0.0000 | 0.0000 | 15 |
| GO:0032200 | telomere organization | 22/588 | 167/17913 | 0.0000 | 0.0000 | 22 |
| GO:0070555 | response to interleukin-1 | 23/588 | 183/17913 | 0.0000 | 0.0000 | 23 |
| GO:0032204 | regulation of telomere maintenance | 15/588 | 79/17913 | 0.0000 | 0.0000 | 15 |
| GO:0031145 | anaphase-promoting complex-dependent catabolic process | 15/588 | 81/17913 | 0.0000 | 0.0000 | 15 |
| GO:0008380 | RNA splicing | 38/588 | 440/17913 | 0.0000 | 0.0000 | 38 |
| GO:0045088 | regulation of innate immune response | 38/588 | 440/17913 | 0.0000 | 0.0000 | 38 |
| GO:2000278 | regulation of DNA biosynthetic process | 17/588 | 106/17913 | 0.0000 | 0.0000 | 17 |
| GO:0014070 | response to organic cyclic compound | 60/588 | 879/17913 | 0.0000 | 0.0000 | 60 |
| GO:0006521 | regulation of cellular amino acid metabolic process | 13/588 | 61/17913 | 0.0000 | 0.0000 | 13 |
| GO:1904356 | regulation of telomere maintenance via telomere lengthening | 13/588 | 61/17913 | 0.0000 | 0.0000 | 13 |
| GO:0033365 | protein localization to organelle | 56/588 | 798/17913 | 0.0000 | 0.0000 | 56 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 16/588 | 95/17913 | 0.0000 | 0.0000 | 16 |
| GO:0006913 | nucleocytoplasmic transport | 30/588 | 302/17913 | 0.0000 | 0.0000 | 30 |
| GO:0048863 | stem cell differentiation | 26/588 | 237/17913 | 0.0000 | 0.0000 | 26 |
| GO:0006457 | protein folding | 22/588 | 176/17913 | 0.0000 | 0.0000 | 22 |
| GO:0006281 | DNA repair | 41/588 | 502/17913 | 0.0000 | 0.0000 | 41 |
| GO:0006325 | chromatin organization | 52/588 | 722/17913 | 0.0000 | 0.0000 | 52 |
| GO:0061013 | regulation of mRNA catabolic process | 22/588 | 178/17913 | 0.0000 | 0.0000 | 22 |
| GO:0070201 | regulation of establishment of protein localization | 52/588 | 723/17913 | 0.0000 | 0.0000 | 52 |
| GO:1902750 | negative regulation of cell cycle G2/M phase transition | 16/588 | 97/17913 | 0.0000 | 0.0000 | 16 |
| GO:0050778 | positive regulation of immune response | 56/588 | 809/17913 | 0.0000 | 0.0000 | 56 |
| GO:1904814 | regulation of protein localization to chromosome, telomeric region | 7/588 | 14/17913 | 0.0000 | 0.0000 | 7 |
| GO:0009894 | regulation of catabolic process | 61/588 | 916/17913 | 0.0000 | 0.0000 | 61 |
| GO:0010035 | response to inorganic substance | 42/588 | 528/17913 | 0.0000 | 0.0000 | 42 |
| GO:0009314 | response to radiation | 37/588 | 435/17913 | 0.0000 | 0.0000 | 37 |
| GO:0062012 | regulation of small molecule metabolic process | 37/588 | 439/17913 | 0.0000 | 0.0000 | 37 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 14/588 | 77/17913 | 0.0000 | 0.0000 | 14 |
| GO:0071347 | cellular response to interleukin-1 | 20/588 | 156/17913 | 0.0000 | 0.0000 | 20 |
| GO:1904874 | positive regulation of telomerase RNA localization to Cajal body | 7/588 | 15/17913 | 0.0000 | 0.0000 | 7 |
| GO:0050821 | protein stabilization | 21/588 | 171/17913 | 0.0000 | 0.0000 | 21 |
| GO:1904358 | positive regulation of telomere maintenance via telomere lengthening | 10/588 | 37/17913 | 0.0000 | 0.0000 | 10 |
| GO:0007417 | central nervous system development | 61/588 | 935/17913 | 0.0000 | 0.0000 | 61 |
| GO:0002220 | innate immune response activating cell surface receptor signaling pathway | 17/588 | 116/17913 | 0.0000 | 0.0000 | 17 |
| GO:0010833 | telomere maintenance via telomere lengthening | 14/588 | 79/17913 | 0.0000 | 0.0000 | 14 |
| GO:0043069 | negative regulation of programmed cell death | 60/588 | 916/17913 | 0.0000 | 0.0000 | 60 |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 13/588 | 69/17913 | 0.0000 | 0.0000 | 13 |
| GO:0031647 | regulation of protein stability | 27/588 | 272/17913 | 0.0000 | 0.0000 | 27 |
| GO:0070200 | establishment of protein localization to telomere | 7/588 | 16/17913 | 0.0000 | 0.0000 | 7 |
| GO:0002237 | response to molecule of bacterial origin | 29/588 | 309/17913 | 0.0000 | 0.0000 | 29 |
| GO:0034622 | cellular protein-containing complex assembly | 61/588 | 952/17913 | 0.0000 | 0.0000 | 61 |
| GO:0010243 | response to organonitrogen compound | 60/588 | 932/17913 | 0.0000 | 0.0000 | 60 |
| GO:0032880 | regulation of protein localization | 62/588 | 979/17913 | 0.0000 | 0.0000 | 62 |
| GO:0030155 | regulation of cell adhesion | 47/588 | 659/17913 | 0.0000 | 0.0000 | 47 |
| GO:0090407 | organophosphate biosynthetic process | 46/588 | 640/17913 | 0.0000 | 0.0000 | 46 |
| GO:0045597 | positive regulation of cell differentiation | 61/588 | 962/17913 | 0.0000 | 0.0000 | 61 |
| GO:0045862 | positive regulation of proteolysis | 30/588 | 333/17913 | 0.0000 | 0.0000 | 30 |
| GO:0032206 | positive regulation of telomere maintenance | 11/588 | 51/17913 | 0.0000 | 0.0000 | 11 |
| GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 17/588 | 124/17913 | 0.0000 | 0.0000 | 17 |
| GO:0009725 | response to hormone | 59/588 | 920/17913 | 0.0000 | 0.0000 | 59 |
| GO:0002764 | immune response-regulating signaling pathway | 44/588 | 603/17913 | 0.0000 | 0.0000 | 44 |
| GO:0006352 | DNA-templated transcription, initiation | 24/588 | 231/17913 | 0.0000 | 0.0000 | 24 |
| GO:0043903 | regulation of symbiosis, encompassing mutualism through parasitism | 24/588 | 232/17913 | 0.0000 | 0.0000 | 24 |
| GO:0007568 | aging | 29/588 | 318/17913 | 0.0000 | 0.0000 | 29 |
| GO:0006278 | RNA-dependent DNA biosynthetic process | 13/588 | 74/17913 | 0.0000 | 0.0000 | 13 |
| GO:0002253 | activation of immune response | 46/588 | 647/17913 | 0.0000 | 0.0000 | 46 |
| GO:0002218 | activation of innate immune response | 29/588 | 319/17913 | 0.0000 | 0.0000 | 29 |
| GO:1903706 | regulation of hemopoiesis | 37/588 | 468/17913 | 0.0000 | 0.0000 | 37 |
| GO:0002223 | stimulatory C-type lectin receptor signaling pathway | 16/588 | 113/17913 | 0.0000 | 0.0000 | 16 |
| GO:0048024 | regulation of mRNA splicing, via spliceosome | 13/588 | 75/17913 | 0.0000 | 0.0000 | 13 |
| GO:1904872 | regulation of telomerase RNA localization to Cajal body | 7/588 | 18/17913 | 0.0000 | 0.0000 | 7 |
| GO:0032210 | regulation of telomere maintenance via telomerase | 11/588 | 53/17913 | 0.0000 | 0.0000 | 11 |
| GO:0002576 | platelet degranulation | 17/588 | 128/17913 | 0.0000 | 0.0000 | 17 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 35/588 | 434/17913 | 0.0000 | 0.0000 | 35 |
| GO:0070498 | interleukin-1-mediated signaling pathway | 15/588 | 101/17913 | 0.0000 | 0.0000 | 15 |
| GO:0032212 | positive regulation of telomere maintenance via telomerase | 9/588 | 34/17913 | 0.0000 | 0.0000 | 9 |
| GO:0071453 | cellular response to oxygen levels | 24/588 | 237/17913 | 0.0000 | 0.0000 | 24 |
| GO:0009165 | nucleotide biosynthetic process | 31/588 | 360/17913 | 0.0000 | 0.0000 | 31 |
| GO:0071478 | cellular response to radiation | 20/588 | 173/17913 | 0.0000 | 0.0000 | 20 |
| GO:0043484 | regulation of RNA splicing | 16/588 | 115/17913 | 0.0000 | 0.0000 | 16 |
| GO:0052547 | regulation of peptidase activity | 33/588 | 398/17913 | 0.0000 | 0.0000 | 33 |
| GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 20/588 | 174/17913 | 0.0000 | 0.0000 | 20 |
| GO:0035690 | cellular response to drug | 31/588 | 362/17913 | 0.0000 | 0.0000 | 31 |
| GO:1902807 | negative regulation of cell cycle G1/S phase transition | 17/588 | 130/17913 | 0.0000 | 0.0000 | 17 |
| GO:0035567 | non-canonical Wnt signaling pathway | 18/588 | 145/17913 | 0.0000 | 0.0000 | 18 |
| GO:0071214 | cellular response to abiotic stimulus | 28/588 | 310/17913 | 0.0000 | 0.0000 | 28 |
| GO:0104004 | cellular response to environmental stimulus | 28/588 | 310/17913 | 0.0000 | 0.0000 | 28 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 23/588 | 224/17913 | 0.0000 | 0.0000 | 23 |
| GO:1901699 | cellular response to nitrogen compound | 44/588 | 620/17913 | 0.0000 | 0.0000 | 44 |
| GO:0019884 | antigen processing and presentation of exogenous antigen | 20/588 | 176/17913 | 0.0000 | 0.0000 | 20 |
| GO:0090670 | RNA localization to Cajal body | 7/588 | 19/17913 | 0.0000 | 0.0000 | 7 |
| GO:0090671 | telomerase RNA localization to Cajal body | 7/588 | 19/17913 | 0.0000 | 0.0000 | 7 |
| GO:0090672 | telomerase RNA localization | 7/588 | 19/17913 | 0.0000 | 0.0000 | 7 |
| GO:0090685 | RNA localization to nucleus | 7/588 | 19/17913 | 0.0000 | 0.0000 | 7 |
| GO:1901293 | nucleoside phosphate biosynthetic process | 31/588 | 365/17913 | 0.0000 | 0.0000 | 31 |
| GO:0042180 | cellular ketone metabolic process | 24/588 | 241/17913 | 0.0000 | 0.0000 | 24 |
| GO:0007004 | telomere maintenance via telomerase | 12/588 | 67/17913 | 0.0000 | 0.0000 | 12 |
| GO:0071456 | cellular response to hypoxia | 22/588 | 210/17913 | 0.0000 | 0.0000 | 22 |
| GO:0034599 | cellular response to oxidative stress | 27/588 | 296/17913 | 0.0000 | 0.0000 | 27 |
| GO:0043900 | regulation of multi-organism process | 33/588 | 408/17913 | 0.0000 | 0.0001 | 33 |
| GO:0008284 | positive regulation of cell proliferation | 58/588 | 931/17913 | 0.0000 | 0.0001 | 58 |
| GO:0009617 | response to bacterium | 42/588 | 588/17913 | 0.0000 | 0.0001 | 42 |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 15/588 | 107/17913 | 0.0000 | 0.0001 | 15 |
| GO:0010720 | positive regulation of cell development | 39/588 | 528/17913 | 0.0000 | 0.0001 | 39 |
| GO:0006353 | DNA-templated transcription, termination | 12/588 | 69/17913 | 0.0000 | 0.0001 | 12 |
| GO:0045089 | positive regulation of innate immune response | 31/588 | 373/17913 | 0.0000 | 0.0001 | 31 |
| GO:0045936 | negative regulation of phosphate metabolic process | 41/588 | 573/17913 | 0.0000 | 0.0001 | 41 |
| GO:0043066 | negative regulation of apoptotic process | 56/588 | 894/17913 | 0.0000 | 0.0001 | 56 |
| GO:0001736 | establishment of planar polarity | 16/588 | 123/17913 | 0.0000 | 0.0001 | 16 |
| GO:0007164 | establishment of tissue polarity | 16/588 | 123/17913 | 0.0000 | 0.0001 | 16 |
| GO:0090175 | regulation of establishment of planar polarity | 15/588 | 109/17913 | 0.0000 | 0.0001 | 15 |
| GO:0042063 | gliogenesis | 26/588 | 285/17913 | 0.0000 | 0.0001 | 26 |
| GO:0010563 | negative regulation of phosphorus metabolic process | 41/588 | 574/17913 | 0.0000 | 0.0001 | 41 |
| GO:0051301 | cell division | 41/588 | 575/17913 | 0.0000 | 0.0001 | 41 |
| GO:0050769 | positive regulation of neurogenesis | 35/588 | 455/17913 | 0.0000 | 0.0001 | 35 |
| GO:0071396 | cellular response to lipid | 41/588 | 576/17913 | 0.0000 | 0.0001 | 41 |
| GO:0002573 | myeloid leukocyte differentiation | 21/588 | 201/17913 | 0.0000 | 0.0001 | 21 |
| GO:0009887 | animal organ morphogenesis | 60/588 | 989/17913 | 0.0000 | 0.0001 | 60 |
| GO:0070661 | leukocyte proliferation | 25/588 | 270/17913 | 0.0000 | 0.0001 | 25 |
| GO:0002429 | immune response-activating cell surface receptor signaling pathway | 32/588 | 399/17913 | 0.0000 | 0.0001 | 32 |
| GO:0051338 | regulation of transferase activity | 56/588 | 903/17913 | 0.0000 | 0.0001 | 56 |
| GO:0036294 | cellular response to decreased oxygen levels | 22/588 | 220/17913 | 0.0000 | 0.0001 | 22 |
| GO:0009611 | response to wounding | 45/588 | 665/17913 | 0.0000 | 0.0001 | 45 |
| GO:0050792 | regulation of viral process | 21/588 | 204/17913 | 0.0000 | 0.0001 | 21 |
| GO:0048002 | antigen processing and presentation of peptide antigen | 20/588 | 188/17913 | 0.0000 | 0.0001 | 20 |
| GO:0006091 | generation of precursor metabolites and energy | 37/588 | 502/17913 | 0.0000 | 0.0001 | 37 |
| GO:0060341 | regulation of cellular localization | 54/588 | 863/17913 | 0.0000 | 0.0001 | 54 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 28/588 | 328/17913 | 0.0000 | 0.0001 | 28 |
| GO:0006520 | cellular amino acid metabolic process | 29/588 | 347/17913 | 0.0000 | 0.0001 | 29 |
| GO:0080135 | regulation of cellular response to stress | 47/588 | 713/17913 | 0.0000 | 0.0001 | 47 |
| GO:0043062 | extracellular structure organization | 31/588 | 387/17913 | 0.0000 | 0.0001 | 31 |
| GO:0006401 | RNA catabolic process | 30/588 | 368/17913 | 0.0000 | 0.0001 | 30 |
| GO:0002757 | immune response-activating signal transduction | 40/588 | 567/17913 | 0.0000 | 0.0001 | 40 |
| GO:0010212 | response to ionizing radiation | 17/588 | 144/17913 | 0.0000 | 0.0001 | 17 |
| GO:0032496 | response to lipopolysaccharide | 26/588 | 295/17913 | 0.0000 | 0.0001 | 26 |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 15/588 | 115/17913 | 0.0000 | 0.0001 | 15 |
| GO:0016579 | protein deubiquitination | 24/588 | 260/17913 | 0.0000 | 0.0001 | 24 |
| GO:0006261 | DNA-dependent DNA replication | 16/588 | 130/17913 | 0.0000 | 0.0001 | 16 |
| GO:0016999 | antibiotic metabolic process | 16/588 | 130/17913 | 0.0000 | 0.0001 | 16 |
| GO:0051050 | positive regulation of transport | 57/588 | 942/17913 | 0.0000 | 0.0001 | 57 |
| GO:0002758 | innate immune response-activating signal transduction | 26/588 | 298/17913 | 0.0000 | 0.0001 | 26 |
| GO:0071241 | cellular response to inorganic substance | 20/588 | 194/17913 | 0.0000 | 0.0001 | 20 |
| GO:0006367 | transcription initiation from RNA polymerase II promoter | 19/588 | 178/17913 | 0.0000 | 0.0001 | 19 |
| GO:0006418 | tRNA aminoacylation for protein translation | 9/588 | 42/17913 | 0.0000 | 0.0002 | 9 |
| GO:0051236 | establishment of RNA localization | 19/588 | 179/17913 | 0.0000 | 0.0002 | 19 |
| GO:0009124 | nucleoside monophosphate biosynthetic process | 20/588 | 196/17913 | 0.0000 | 0.0002 | 20 |
| GO:0050852 | T cell receptor signaling pathway | 19/588 | 180/17913 | 0.0000 | 0.0002 | 19 |
| GO:0051345 | positive regulation of hydrolase activity | 45/588 | 684/17913 | 0.0000 | 0.0002 | 45 |
| GO:0034614 | cellular response to reactive oxygen species | 18/588 | 165/17913 | 0.0000 | 0.0002 | 18 |
| GO:0008334 | histone mRNA metabolic process | 7/588 | 24/17913 | 0.0000 | 0.0002 | 7 |
| GO:0070199 | establishment of protein localization to chromosome | 7/588 | 24/17913 | 0.0000 | 0.0002 | 7 |
| GO:0051962 | positive regulation of nervous system development | 37/588 | 519/17913 | 0.0000 | 0.0002 | 37 |
| GO:2000027 | regulation of animal organ morphogenesis | 23/588 | 250/17913 | 0.0000 | 0.0002 | 23 |
| GO:0010942 | positive regulation of cell death | 46/588 | 710/17913 | 0.0000 | 0.0002 | 46 |
| GO:0044283 | small molecule biosynthetic process | 47/588 | 732/17913 | 0.0000 | 0.0002 | 47 |
| GO:0043408 | regulation of MAPK cascade | 45/588 | 689/17913 | 0.0000 | 0.0002 | 45 |
| GO:0048511 | rhythmic process | 25/588 | 287/17913 | 0.0000 | 0.0002 | 25 |
| GO:0030217 | T cell differentiation | 22/588 | 234/17913 | 0.0000 | 0.0002 | 22 |
| GO:0030098 | lymphocyte differentiation | 27/588 | 325/17913 | 0.0000 | 0.0002 | 27 |
| GO:0010332 | response to gamma radiation | 10/588 | 55/17913 | 0.0000 | 0.0002 | 10 |
| GO:0007623 | circadian rhythm | 20/588 | 201/17913 | 0.0000 | 0.0002 | 20 |
| GO:0007420 | brain development | 45/588 | 694/17913 | 0.0000 | 0.0002 | 45 |
| GO:0043065 | positive regulation of apoptotic process | 43/588 | 652/17913 | 0.0000 | 0.0002 | 43 |
| GO:0070997 | neuron death | 28/588 | 347/17913 | 0.0000 | 0.0002 | 28 |
| GO:0055086 | nucleobase-containing small molecule metabolic process | 47/588 | 740/17913 | 0.0000 | 0.0002 | 47 |
| GO:0070646 | protein modification by small protein removal | 24/588 | 273/17913 | 0.0000 | 0.0002 | 24 |
| GO:0009117 | nucleotide metabolic process | 43/588 | 654/17913 | 0.0000 | 0.0002 | 43 |
| GO:0043039 | tRNA aminoacylation | 9/588 | 45/17913 | 0.0000 | 0.0003 | 9 |
| GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 14/588 | 109/17913 | 0.0000 | 0.0003 | 14 |
| GO:0001738 | morphogenesis of a polarized epithelium | 16/588 | 139/17913 | 0.0000 | 0.0003 | 16 |
| GO:1903827 | regulation of cellular protein localization | 36/588 | 509/17913 | 0.0000 | 0.0003 | 36 |
| GO:2001251 | negative regulation of chromosome organization | 15/588 | 125/17913 | 0.0000 | 0.0003 | 15 |
| GO:0034504 | protein localization to nucleus | 21/588 | 223/17913 | 0.0000 | 0.0003 | 21 |
| GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 25/588 | 295/17913 | 0.0000 | 0.0003 | 25 |
| GO:0043038 | amino acid activation | 9/588 | 46/17913 | 0.0000 | 0.0003 | 9 |
| GO:0043068 | positive regulation of programmed cell death | 43/588 | 660/17913 | 0.0000 | 0.0003 | 43 |
| GO:0038093 | Fc receptor signaling pathway | 22/588 | 241/17913 | 0.0000 | 0.0003 | 22 |
| GO:0030198 | extracellular matrix organization | 27/588 | 334/17913 | 0.0000 | 0.0003 | 27 |
| GO:0045787 | positive regulation of cell cycle | 29/588 | 373/17913 | 0.0000 | 0.0003 | 29 |
| GO:0006753 | nucleoside phosphate metabolic process | 43/588 | 663/17913 | 0.0000 | 0.0003 | 43 |
| GO:0035966 | response to topologically incorrect protein | 18/588 | 175/17913 | 0.0000 | 0.0004 | 18 |
| GO:0046651 | lymphocyte proliferation | 22/588 | 244/17913 | 0.0000 | 0.0004 | 22 |
| GO:0042326 | negative regulation of phosphorylation | 33/588 | 455/17913 | 0.0000 | 0.0004 | 33 |
| GO:0045732 | positive regulation of protein catabolic process | 19/588 | 192/17913 | 0.0000 | 0.0004 | 19 |
| GO:0071417 | cellular response to organonitrogen compound | 38/588 | 559/17913 | 0.0000 | 0.0004 | 38 |
| GO:0071482 | cellular response to light stimulus | 14/588 | 113/17913 | 0.0000 | 0.0004 | 14 |
| GO:0050657 | nucleic acid transport | 18/588 | 176/17913 | 0.0000 | 0.0004 | 18 |
| GO:0050658 | RNA transport | 18/588 | 176/17913 | 0.0000 | 0.0004 | 18 |
| GO:0044087 | regulation of cellular component biogenesis | 53/588 | 891/17913 | 0.0000 | 0.0004 | 53 |
| GO:0072331 | signal transduction by p53 class mediator | 23/588 | 264/17913 | 0.0000 | 0.0004 | 23 |
| GO:0032943 | mononuclear cell proliferation | 22/588 | 246/17913 | 0.0000 | 0.0004 | 22 |
| GO:1903364 | positive regulation of cellular protein catabolic process | 15/588 | 129/17913 | 0.0000 | 0.0004 | 15 |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 18/588 | 177/17913 | 0.0000 | 0.0004 | 18 |
| GO:0032069 | regulation of nuclease activity | 6/588 | 19/17913 | 0.0000 | 0.0004 | 6 |
| GO:0010565 | regulation of cellular ketone metabolic process | 18/588 | 178/17913 | 0.0000 | 0.0004 | 18 |
| GO:1904951 | positive regulation of establishment of protein localization | 32/588 | 440/17913 | 0.0000 | 0.0004 | 32 |
| GO:0060322 | head development | 46/588 | 738/17913 | 0.0000 | 0.0004 | 46 |
| GO:0000302 | response to reactive oxygen species | 21/588 | 230/17913 | 0.0000 | 0.0004 | 21 |
| GO:1903362 | regulation of cellular protein catabolic process | 21/588 | 230/17913 | 0.0000 | 0.0004 | 21 |
| GO:0051095 | regulation of helicase activity | 5/588 | 12/17913 | 0.0000 | 0.0004 | 5 |
| GO:0006979 | response to oxidative stress | 32/588 | 442/17913 | 0.0000 | 0.0005 | 32 |
| GO:0010498 | proteasomal protein catabolic process | 29/588 | 382/17913 | 0.0000 | 0.0005 | 29 |
| GO:0032922 | circadian regulation of gene expression | 10/588 | 61/17913 | 0.0000 | 0.0005 | 10 |
| GO:0043902 | positive regulation of multi-organism process | 18/588 | 180/17913 | 0.0000 | 0.0005 | 18 |
| GO:0001817 | regulation of cytokine production | 44/588 | 698/17913 | 0.0000 | 0.0005 | 44 |
| GO:0006275 | regulation of DNA replication | 13/588 | 102/17913 | 0.0000 | 0.0005 | 13 |
| GO:0006289 | nucleotide-excision repair | 13/588 | 102/17913 | 0.0000 | 0.0005 | 13 |
| GO:1905330 | regulation of morphogenesis of an epithelium | 18/588 | 181/17913 | 0.0000 | 0.0005 | 18 |
| GO:0048524 | positive regulation of viral process | 13/588 | 103/17913 | 0.0000 | 0.0005 | 13 |
| GO:0001934 | positive regulation of protein phosphorylation | 53/588 | 907/17913 | 0.0000 | 0.0006 | 53 |
| GO:0031347 | regulation of defense response | 52/588 | 885/17913 | 0.0000 | 0.0006 | 52 |
| GO:0098781 | ncRNA transcription | 13/588 | 104/17913 | 0.0000 | 0.0006 | 13 |
| GO:0032508 | DNA duplex unwinding | 11/588 | 76/17913 | 0.0000 | 0.0006 | 11 |
| GO:0061136 | regulation of proteasomal protein catabolic process | 17/588 | 167/17913 | 0.0000 | 0.0006 | 17 |
| GO:0050764 | regulation of phagocytosis | 12/588 | 90/17913 | 0.0000 | 0.0006 | 12 |
| GO:0031349 | positive regulation of defense response | 35/588 | 512/17913 | 0.0000 | 0.0006 | 35 |
| GO:0009266 | response to temperature stimulus | 20/588 | 219/17913 | 0.0000 | 0.0006 | 20 |
| GO:0052548 | regulation of endopeptidase activity | 28/588 | 370/17913 | 0.0000 | 0.0006 | 28 |
| GO:0030099 | myeloid cell differentiation | 30/588 | 411/17913 | 0.0000 | 0.0007 | 30 |
| GO:1901214 | regulation of neuron death | 25/588 | 313/17913 | 0.0000 | 0.0007 | 25 |
| GO:0006270 | DNA replication initiation | 7/588 | 30/17913 | 0.0000 | 0.0007 | 7 |
| GO:0015931 | nucleobase-containing compound transport | 20/588 | 221/17913 | 0.0000 | 0.0007 | 20 |
| GO:0071826 | ribonucleoprotein complex subunit organization | 20/588 | 221/17913 | 0.0000 | 0.0007 | 20 |
| GO:0006354 | DNA-templated transcription, elongation | 13/588 | 106/17913 | 0.0000 | 0.0007 | 13 |
| GO:0008584 | male gonad development | 15/588 | 137/17913 | 0.0000 | 0.0007 | 15 |
| GO:0009411 | response to UV | 15/588 | 137/17913 | 0.0000 | 0.0007 | 15 |
| GO:0071824 | protein-DNA complex subunit organization | 21/588 | 240/17913 | 0.0000 | 0.0007 | 21 |
| GO:0042176 | regulation of protein catabolic process | 27/588 | 354/17913 | 0.0000 | 0.0007 | 27 |
| GO:0070317 | negative regulation of G0 to G1 transition | 8/588 | 41/17913 | 0.0000 | 0.0008 | 8 |
| GO:0031056 | regulation of histone modification | 15/588 | 138/17913 | 0.0000 | 0.0008 | 15 |
| GO:0046546 | development of primary male sexual characteristics | 15/588 | 138/17913 | 0.0000 | 0.0008 | 15 |
| GO:0009636 | response to toxic substance | 34/588 | 499/17913 | 0.0001 | 0.0008 | 34 |
| GO:1901800 | positive regulation of proteasomal protein catabolic process | 12/588 | 93/17913 | 0.0001 | 0.0008 | 12 |
| GO:0006368 | transcription elongation from RNA polymerase II promoter | 11/588 | 79/17913 | 0.0001 | 0.0008 | 11 |
| GO:0043549 | regulation of kinase activity | 48/588 | 808/17913 | 0.0001 | 0.0008 | 48 |
| GO:0040007 | growth | 54/588 | 948/17913 | 0.0001 | 0.0009 | 54 |
| GO:0051347 | positive regulation of transferase activity | 39/588 | 609/17913 | 0.0001 | 0.0009 | 39 |
| GO:0001816 | cytokine production | 46/588 | 765/17913 | 0.0001 | 0.0009 | 46 |
| GO:0006310 | DNA recombination | 21/588 | 244/17913 | 0.0001 | 0.0009 | 21 |
| GO:0033151 | V(D)J recombination | 5/588 | 14/17913 | 0.0001 | 0.0009 | 5 |
| GO:0006518 | peptide metabolic process | 48/588 | 811/17913 | 0.0001 | 0.0009 | 48 |
| GO:0002440 | production of molecular mediator of immune response | 18/588 | 191/17913 | 0.0001 | 0.0009 | 18 |
| GO:0051170 | import into nucleus | 14/588 | 125/17913 | 0.0001 | 0.0010 | 14 |
| GO:0022618 | ribonucleoprotein complex assembly | 19/588 | 209/17913 | 0.0001 | 0.0010 | 19 |
| GO:0019725 | cellular homeostasis | 48/588 | 814/17913 | 0.0001 | 0.0010 | 48 |
| GO:0002285 | lymphocyte activation involved in immune response | 16/588 | 158/17913 | 0.0001 | 0.0010 | 16 |
| GO:0065004 | protein-DNA complex assembly | 19/588 | 210/17913 | 0.0001 | 0.0010 | 19 |
| GO:0042327 | positive regulation of phosphorylation | 54/588 | 955/17913 | 0.0001 | 0.0010 | 54 |
| GO:0097327 | response to antineoplastic agent | 12/588 | 96/17913 | 0.0001 | 0.0011 | 12 |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 18/588 | 194/17913 | 0.0001 | 0.0011 | 18 |
| GO:1902806 | regulation of cell cycle G1/S phase transition | 18/588 | 195/17913 | 0.0001 | 0.0012 | 18 |
| GO:1903312 | negative regulation of mRNA metabolic process | 10/588 | 69/17913 | 0.0001 | 0.0012 | 10 |
| GO:0030163 | protein catabolic process | 47/588 | 799/17913 | 0.0001 | 0.0012 | 47 |
| GO:0006986 | response to unfolded protein | 16/588 | 161/17913 | 0.0001 | 0.0012 | 16 |
| GO:0009416 | response to light stimulus | 24/588 | 307/17913 | 0.0001 | 0.0012 | 24 |
| GO:0038061 | NIK/NF-kappaB signaling | 17/588 | 179/17913 | 0.0001 | 0.0013 | 17 |
| GO:0045859 | regulation of protein kinase activity | 44/588 | 733/17913 | 0.0001 | 0.0013 | 44 |
| GO:0045785 | positive regulation of cell adhesion | 28/588 | 388/17913 | 0.0001 | 0.0013 | 28 |
| GO:0046677 | response to antibiotic | 25/588 | 328/17913 | 0.0001 | 0.0013 | 25 |
| GO:0042113 | B cell activation | 19/588 | 215/17913 | 0.0001 | 0.0013 | 19 |
| GO:0044786 | cell cycle DNA replication | 9/588 | 57/17913 | 0.0001 | 0.0013 | 9 |
| GO:0022407 | regulation of cell-cell adhesion | 28/588 | 389/17913 | 0.0001 | 0.0013 | 28 |
| GO:0009123 | nucleoside monophosphate metabolic process | 26/588 | 349/17913 | 0.0001 | 0.0014 | 26 |
| GO:0070316 | regulation of G0 to G1 transition | 8/588 | 45/17913 | 0.0001 | 0.0014 | 8 |
| GO:0016571 | histone methylation | 14/588 | 130/17913 | 0.0001 | 0.0014 | 14 |
| GO:1903050 | regulation of proteolysis involved in cellular protein catabolic process | 18/588 | 198/17913 | 0.0001 | 0.0014 | 18 |
| GO:0001101 | response to acid chemical | 25/588 | 330/17913 | 0.0001 | 0.0014 | 25 |
| GO:0032870 | cellular response to hormone stimulus | 40/588 | 647/17913 | 0.0001 | 0.0014 | 40 |
| GO:0044257 | cellular protein catabolic process | 40/588 | 648/17913 | 0.0001 | 0.0014 | 40 |
| GO:0002449 | lymphocyte mediated immunity | 23/588 | 293/17913 | 0.0001 | 0.0015 | 23 |
| GO:1902275 | regulation of chromatin organization | 16/588 | 165/17913 | 0.0001 | 0.0016 | 16 |
| GO:0061614 | pri-miRNA transcription by RNA polymerase II | 8/588 | 46/17913 | 0.0001 | 0.0016 | 8 |
| GO:0009991 | response to extracellular stimulus | 33/588 | 498/17913 | 0.0001 | 0.0016 | 33 |
| GO:0007569 | cell aging | 13/588 | 116/17913 | 0.0001 | 0.0016 | 13 |
| GO:1901998 | toxin transport | 7/588 | 35/17913 | 0.0001 | 0.0017 | 7 |
| GO:0006220 | pyrimidine nucleotide metabolic process | 9/588 | 59/17913 | 0.0001 | 0.0017 | 9 |
| GO:0048545 | response to steroid hormone | 27/588 | 375/17913 | 0.0001 | 0.0017 | 27 |
| GO:0043632 | modification-dependent macromolecule catabolic process | 34/588 | 522/17913 | 0.0001 | 0.0017 | 34 |
| GO:0010038 | response to metal ion | 25/588 | 335/17913 | 0.0001 | 0.0017 | 25 |
| GO:0006283 | transcription-coupled nucleotide-excision repair | 10/588 | 73/17913 | 0.0001 | 0.0018 | 10 |
| GO:0033260 | nuclear DNA replication | 8/588 | 47/17913 | 0.0001 | 0.0018 | 8 |
| GO:0045023 | G0 to G1 transition | 8/588 | 47/17913 | 0.0001 | 0.0018 | 8 |
| GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 9/588 | 60/17913 | 0.0001 | 0.0019 | 9 |
| GO:0016444 | somatic cell DNA recombination | 9/588 | 60/17913 | 0.0001 | 0.0019 | 9 |
| GO:0050766 | positive regulation of phagocytosis | 9/588 | 60/17913 | 0.0001 | 0.0019 | 9 |
| GO:0006402 | mRNA catabolic process | 25/588 | 338/17913 | 0.0001 | 0.0019 | 25 |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway | 14/588 | 135/17913 | 0.0001 | 0.0019 | 14 |
| GO:0006479 | protein methylation | 16/588 | 169/17913 | 0.0001 | 0.0020 | 16 |
| GO:0008213 | protein alkylation | 16/588 | 169/17913 | 0.0001 | 0.0020 | 16 |
| GO:0038095 | Fc-epsilon receptor signaling pathway | 16/588 | 169/17913 | 0.0001 | 0.0020 | 16 |
| GO:0032481 | positive regulation of type I interferon production | 10/588 | 74/17913 | 0.0001 | 0.0020 | 10 |
| GO:0002009 | morphogenesis of an epithelium | 34/588 | 527/17913 | 0.0001 | 0.0020 | 34 |
| GO:0043687 | post-translational protein modification | 26/588 | 360/17913 | 0.0002 | 0.0021 | 26 |
| GO:0044089 | positive regulation of cellular component biogenesis | 33/588 | 507/17913 | 0.0002 | 0.0021 | 33 |
| GO:0071216 | cellular response to biotic stimulus | 18/588 | 206/17913 | 0.0002 | 0.0021 | 18 |
| GO:0060284 | regulation of cell development | 50/588 | 893/17913 | 0.0002 | 0.0022 | 50 |
| GO:0097435 | supramolecular fiber organization | 35/588 | 553/17913 | 0.0002 | 0.0023 | 35 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 33/588 | 510/17913 | 0.0002 | 0.0023 | 33 |
| GO:0071407 | cellular response to organic cyclic compound | 34/588 | 533/17913 | 0.0002 | 0.0024 | 34 |
| GO:0031960 | response to corticosteroid | 15/588 | 155/17913 | 0.0002 | 0.0024 | 15 |
| GO:0046390 | ribose phosphate biosynthetic process | 22/588 | 284/17913 | 0.0002 | 0.0024 | 22 |
| GO:1903409 | reactive oxygen species biosynthetic process | 13/588 | 122/17913 | 0.0002 | 0.0024 | 13 |
| GO:0019058 | viral life cycle | 24/588 | 324/17913 | 0.0002 | 0.0024 | 24 |
| GO:0045861 | negative regulation of proteolysis | 24/588 | 324/17913 | 0.0002 | 0.0024 | 24 |
| GO:1901652 | response to peptide | 32/588 | 491/17913 | 0.0002 | 0.0025 | 32 |
| GO:0050865 | regulation of cell activation | 34/588 | 535/17913 | 0.0002 | 0.0025 | 34 |
| GO:0051384 | response to glucocorticoid | 14/588 | 139/17913 | 0.0002 | 0.0025 | 14 |
| GO:0050686 | negative regulation of mRNA processing | 6/588 | 27/17913 | 0.0002 | 0.0026 | 6 |
| GO:0032479 | regulation of type I interferon production | 13/588 | 123/17913 | 0.0002 | 0.0026 | 13 |
| GO:0034644 | cellular response to UV | 10/588 | 77/17913 | 0.0002 | 0.0026 | 10 |
| GO:0032873 | negative regulation of stress-activated MAPK cascade | 8/588 | 50/17913 | 0.0002 | 0.0026 | 8 |
| GO:0070303 | negative regulation of stress-activated protein kinase signaling cascade | 8/588 | 50/17913 | 0.0002 | 0.0026 | 8 |
| GO:0009162 | deoxyribonucleoside monophosphate metabolic process | 4/588 | 10/17913 | 0.0002 | 0.0026 | 4 |
| GO:0019941 | modification-dependent protein catabolic process | 33/588 | 515/17913 | 0.0002 | 0.0026 | 33 |
| GO:0072594 | establishment of protein localization to organelle | 30/588 | 452/17913 | 0.0002 | 0.0028 | 30 |
| GO:0046782 | regulation of viral transcription | 9/588 | 64/17913 | 0.0002 | 0.0029 | 9 |
| GO:0072593 | reactive oxygen species metabolic process | 21/588 | 269/17913 | 0.0002 | 0.0029 | 21 |
| GO:0006323 | DNA packaging | 17/588 | 194/17913 | 0.0002 | 0.0029 | 17 |
| GO:0048146 | positive regulation of fibroblast proliferation | 8/588 | 51/17913 | 0.0002 | 0.0029 | 8 |
| GO:0097366 | response to bronchodilator | 8/588 | 51/17913 | 0.0002 | 0.0029 | 8 |
| GO:0032606 | type I interferon production | 13/588 | 125/17913 | 0.0002 | 0.0030 | 13 |
| GO:0034968 | histone lysine methylation | 12/588 | 109/17913 | 0.0002 | 0.0030 | 12 |
| GO:1903052 | positive regulation of proteolysis involved in cellular protein catabolic process | 12/588 | 109/17913 | 0.0002 | 0.0030 | 12 |
| GO:0050767 | regulation of neurogenesis | 44/588 | 768/17913 | 0.0002 | 0.0031 | 44 |
| GO:0042098 | T cell proliferation | 16/588 | 177/17913 | 0.0002 | 0.0031 | 16 |
| GO:0051223 | regulation of protein transport | 40/588 | 677/17913 | 0.0003 | 0.0031 | 40 |
| GO:0048709 | oligodendrocyte differentiation | 11/588 | 94/17913 | 0.0003 | 0.0031 | 11 |
| GO:0050878 | regulation of body fluid levels | 32/588 | 499/17913 | 0.0003 | 0.0031 | 32 |
| GO:0072522 | purine-containing compound biosynthetic process | 22/588 | 291/17913 | 0.0003 | 0.0031 | 22 |
| GO:0046661 | male sex differentiation | 15/588 | 160/17913 | 0.0003 | 0.0031 | 15 |
| GO:0098727 | maintenance of cell number | 15/588 | 160/17913 | 0.0003 | 0.0031 | 15 |
| GO:0032989 | cellular component morphogenesis | 52/588 | 960/17913 | 0.0003 | 0.0033 | 52 |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | 36/588 | 590/17913 | 0.0003 | 0.0034 | 36 |
| GO:0034976 | response to endoplasmic reticulum stress | 20/588 | 254/17913 | 0.0003 | 0.0035 | 20 |
| GO:1902893 | regulation of pri-miRNA transcription by RNA polymerase II | 7/588 | 40/17913 | 0.0003 | 0.0035 | 7 |
| GO:0090087 | regulation of peptide transport | 41/588 | 706/17913 | 0.0003 | 0.0036 | 41 |
| GO:0009262 | deoxyribonucleotide metabolic process | 6/588 | 29/17913 | 0.0003 | 0.0036 | 6 |
| GO:0008406 | gonad development | 18/588 | 217/17913 | 0.0003 | 0.0036 | 18 |
| GO:0030968 | endoplasmic reticulum unfolded protein response | 12/588 | 112/17913 | 0.0003 | 0.0037 | 12 |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 22/588 | 295/17913 | 0.0003 | 0.0037 | 22 |
| GO:0019042 | viral latency | 4/588 | 11/17913 | 0.0003 | 0.0038 | 4 |
| GO:0007599 | hemostasis | 24/588 | 336/17913 | 0.0003 | 0.0038 | 24 |
| GO:0042060 | wound healing | 34/588 | 550/17913 | 0.0003 | 0.0038 | 34 |
| GO:0002697 | regulation of immune effector process | 29/588 | 441/17913 | 0.0003 | 0.0038 | 29 |
| GO:0002200 | somatic diversification of immune receptors | 9/588 | 67/17913 | 0.0003 | 0.0038 | 9 |
| GO:0055114 | oxidation-reduction process | 51/588 | 944/17913 | 0.0003 | 0.0039 | 51 |
| GO:0006935 | chemotaxis | 34/588 | 551/17913 | 0.0003 | 0.0039 | 34 |
| GO:0050434 | positive regulation of viral transcription | 7/588 | 41/17913 | 0.0003 | 0.0039 | 7 |
| GO:0051402 | neuron apoptotic process | 19/588 | 238/17913 | 0.0003 | 0.0040 | 19 |
| GO:0000902 | cell morphogenesis | 48/588 | 874/17913 | 0.0003 | 0.0040 | 48 |
| GO:0006970 | response to osmotic stress | 10/588 | 82/17913 | 0.0003 | 0.0040 | 10 |
| GO:0032386 | regulation of intracellular transport | 27/588 | 400/17913 | 0.0003 | 0.0040 | 27 |
| GO:1903829 | positive regulation of cellular protein localization | 23/588 | 318/17913 | 0.0004 | 0.0041 | 23 |
| GO:0042330 | taxis | 34/588 | 553/17913 | 0.0004 | 0.0041 | 34 |
| GO:0071219 | cellular response to molecule of bacterial origin | 16/588 | 183/17913 | 0.0004 | 0.0042 | 16 |
| GO:0006304 | DNA modification | 12/588 | 114/17913 | 0.0004 | 0.0042 | 12 |
| GO:0002377 | immunoglobulin production | 11/588 | 98/17913 | 0.0004 | 0.0042 | 11 |
| GO:0031667 | response to nutrient levels | 30/588 | 466/17913 | 0.0004 | 0.0042 | 30 |
| GO:0010543 | regulation of platelet activation | 6/588 | 30/17913 | 0.0004 | 0.0042 | 6 |
| GO:1902895 | positive regulation of pri-miRNA transcription by RNA polymerase II | 6/588 | 30/17913 | 0.0004 | 0.0042 | 6 |
| GO:0019216 | regulation of lipid metabolic process | 27/588 | 402/17913 | 0.0004 | 0.0042 | 27 |
| GO:0002320 | lymphoid progenitor cell differentiation | 5/588 | 20/17913 | 0.0004 | 0.0044 | 5 |
| GO:0048872 | homeostasis of number of cells | 19/588 | 241/17913 | 0.0004 | 0.0045 | 19 |
| GO:0033077 | T cell differentiation in thymus | 9/588 | 69/17913 | 0.0004 | 0.0046 | 9 |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | 15/588 | 167/17913 | 0.0004 | 0.0046 | 15 |
| GO:0071248 | cellular response to metal ion | 15/588 | 167/17913 | 0.0004 | 0.0046 | 15 |
| GO:0048608 | reproductive structure development | 28/588 | 426/17913 | 0.0004 | 0.0046 | 28 |
| GO:0045137 | development of primary sexual characteristics | 18/588 | 223/17913 | 0.0004 | 0.0047 | 18 |
| GO:1901653 | cellular response to peptide | 25/588 | 364/17913 | 0.0004 | 0.0049 | 25 |
| GO:0009615 | response to virus | 23/588 | 323/17913 | 0.0004 | 0.0050 | 23 |
| GO:0006369 | termination of RNA polymerase II transcription | 6/588 | 31/17913 | 0.0004 | 0.0050 | 6 |
| GO:0048871 | multicellular organismal homeostasis | 30/588 | 472/17913 | 0.0005 | 0.0051 | 30 |
| GO:0061458 | reproductive system development | 28/588 | 429/17913 | 0.0005 | 0.0051 | 28 |
| GO:0031330 | negative regulation of cellular catabolic process | 19/588 | 244/17913 | 0.0005 | 0.0051 | 19 |
| GO:1900180 | regulation of protein localization to nucleus | 12/588 | 117/17913 | 0.0005 | 0.0051 | 12 |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 15/588 | 169/17913 | 0.0005 | 0.0051 | 15 |
| GO:0034612 | response to tumor necrosis factor | 21/588 | 284/17913 | 0.0005 | 0.0052 | 21 |
| GO:0009156 | ribonucleoside monophosphate biosynthetic process | 16/588 | 188/17913 | 0.0005 | 0.0053 | 16 |
| GO:0007063 | regulation of sister chromatid cohesion | 5/588 | 21/17913 | 0.0005 | 0.0054 | 5 |
| GO:0030177 | positive regulation of Wnt signaling pathway | 15/588 | 170/17913 | 0.0005 | 0.0054 | 15 |
| GO:0035967 | cellular response to topologically incorrect protein | 13/588 | 135/17913 | 0.0005 | 0.0055 | 13 |
| GO:0045576 | mast cell activation | 8/588 | 57/17913 | 0.0005 | 0.0056 | 8 |
| GO:0072431 | signal transduction involved in mitotic G1 DNA damage checkpoint | 8/588 | 57/17913 | 0.0005 | 0.0056 | 8 |
| GO:1902400 | intracellular signal transduction involved in G1 DNA damage checkpoint | 8/588 | 57/17913 | 0.0005 | 0.0056 | 8 |
| GO:0071356 | cellular response to tumor necrosis factor | 20/588 | 266/17913 | 0.0005 | 0.0056 | 20 |
| GO:0071346 | cellular response to interferon-gamma | 14/588 | 153/17913 | 0.0005 | 0.0057 | 14 |
| GO:0030851 | granulocyte differentiation | 6/588 | 32/17913 | 0.0005 | 0.0057 | 6 |
| GO:0009267 | cellular response to starvation | 13/588 | 136/17913 | 0.0005 | 0.0058 | 13 |
| GO:0007159 | leukocyte cell-cell adhesion | 23/588 | 328/17913 | 0.0006 | 0.0059 | 23 |
| GO:0048729 | tissue morphogenesis | 37/588 | 635/17913 | 0.0006 | 0.0060 | 37 |
| GO:0001659 | temperature homeostasis | 15/588 | 172/17913 | 0.0006 | 0.0060 | 15 |
| GO:0035019 | somatic stem cell population maintenance | 9/588 | 72/17913 | 0.0006 | 0.0060 | 9 |
| GO:1901654 | response to ketone | 16/588 | 191/17913 | 0.0006 | 0.0062 | 16 |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 30/588 | 479/17913 | 0.0006 | 0.0062 | 30 |
| GO:0019079 | viral genome replication | 12/588 | 120/17913 | 0.0006 | 0.0062 | 12 |
| GO:0009790 | embryo development | 51/588 | 968/17913 | 0.0006 | 0.0062 | 51 |
| GO:0061024 | membrane organization | 41/588 | 730/17913 | 0.0006 | 0.0063 | 41 |
| GO:0034341 | response to interferon-gamma | 15/588 | 173/17913 | 0.0006 | 0.0063 | 15 |
| GO:0002286 | T cell activation involved in immune response | 10/588 | 88/17913 | 0.0006 | 0.0064 | 10 |
| GO:0002456 | T cell mediated immunity | 10/588 | 88/17913 | 0.0006 | 0.0064 | 10 |
| GO:0031058 | positive regulation of histone modification | 10/588 | 88/17913 | 0.0006 | 0.0064 | 10 |
| GO:0048714 | positive regulation of oligodendrocyte differentiation | 5/588 | 22/17913 | 0.0006 | 0.0065 | 5 |
| GO:0007596 | blood coagulation | 23/588 | 331/17913 | 0.0006 | 0.0065 | 23 |
| GO:0009410 | response to xenobiotic stimulus | 20/588 | 270/17913 | 0.0006 | 0.0065 | 20 |
| GO:0010001 | glial cell differentiation | 17/588 | 212/17913 | 0.0007 | 0.0067 | 17 |
| GO:0072413 | signal transduction involved in mitotic cell cycle checkpoint | 8/588 | 59/17913 | 0.0007 | 0.0067 | 8 |
| GO:1902402 | signal transduction involved in mitotic DNA damage checkpoint | 8/588 | 59/17913 | 0.0007 | 0.0067 | 8 |
| GO:1902403 | signal transduction involved in mitotic DNA integrity checkpoint | 8/588 | 59/17913 | 0.0007 | 0.0067 | 8 |
| GO:0043086 | negative regulation of catalytic activity | 42/588 | 757/17913 | 0.0007 | 0.0067 | 42 |
| GO:0031668 | cellular response to extracellular stimulus | 19/588 | 251/17913 | 0.0007 | 0.0067 | 19 |
| GO:0044728 | DNA methylation or demethylation | 10/588 | 89/17913 | 0.0007 | 0.0068 | 10 |
| GO:0060968 | regulation of gene silencing | 13/588 | 139/17913 | 0.0007 | 0.0068 | 13 |
| GO:0007006 | mitochondrial membrane organization | 12/588 | 122/17913 | 0.0007 | 0.0069 | 12 |
| GO:0018022 | peptidyl-lysine methylation | 12/588 | 122/17913 | 0.0007 | 0.0069 | 12 |
| GO:0030193 | regulation of blood coagulation | 9/588 | 74/17913 | 0.0007 | 0.0070 | 9 |
| GO:1900182 | positive regulation of protein localization to nucleus | 9/588 | 74/17913 | 0.0007 | 0.0070 | 9 |
| GO:0045666 | positive regulation of neuron differentiation | 24/588 | 355/17913 | 0.0007 | 0.0072 | 24 |
| GO:0051168 | nuclear export | 15/588 | 176/17913 | 0.0007 | 0.0072 | 15 |
| GO:0071222 | cellular response to lipopolysaccharide | 15/588 | 176/17913 | 0.0007 | 0.0072 | 15 |
| GO:0043200 | response to amino acid | 11/588 | 106/17913 | 0.0007 | 0.0073 | 11 |
| GO:0009408 | response to heat | 14/588 | 158/17913 | 0.0007 | 0.0073 | 14 |
| GO:0019827 | stem cell population maintenance | 14/588 | 158/17913 | 0.0007 | 0.0073 | 14 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 17/588 | 214/17913 | 0.0007 | 0.0073 | 17 |
| GO:0034620 | cellular response to unfolded protein | 12/588 | 123/17913 | 0.0007 | 0.0073 | 12 |
| GO:0006412 | translation | 38/588 | 668/17913 | 0.0007 | 0.0074 | 38 |
| GO:1900046 | regulation of hemostasis | 9/588 | 75/17913 | 0.0008 | 0.0076 | 9 |
| GO:0045807 | positive regulation of endocytosis | 13/588 | 141/17913 | 0.0008 | 0.0076 | 13 |
| GO:0007064 | mitotic sister chromatid cohesion | 5/588 | 23/17913 | 0.0008 | 0.0076 | 5 |
| GO:2000637 | positive regulation of gene silencing by miRNA | 5/588 | 23/17913 | 0.0008 | 0.0076 | 5 |
| GO:0043043 | peptide biosynthetic process | 39/588 | 693/17913 | 0.0008 | 0.0077 | 39 |
| GO:0048589 | developmental growth | 36/588 | 624/17913 | 0.0008 | 0.0078 | 36 |
| GO:0050817 | coagulation | 23/588 | 337/17913 | 0.0008 | 0.0078 | 23 |
| GO:0035821 | modification of morphology or physiology of other organism | 14/588 | 160/17913 | 0.0008 | 0.0081 | 14 |
| GO:0042692 | muscle cell differentiation | 24/588 | 359/17913 | 0.0008 | 0.0081 | 24 |
| GO:0014015 | positive regulation of gliogenesis | 9/588 | 76/17913 | 0.0008 | 0.0082 | 9 |
| GO:0001819 | positive regulation of cytokine production | 28/588 | 446/17913 | 0.0008 | 0.0083 | 28 |
| GO:2001022 | positive regulation of response to DNA damage stimulus | 10/588 | 92/17913 | 0.0009 | 0.0084 | 10 |
| GO:0007339 | binding of sperm to zona pellucida | 6/588 | 35/17913 | 0.0009 | 0.0085 | 6 |
| GO:0045740 | positive regulation of DNA replication | 6/588 | 35/17913 | 0.0009 | 0.0085 | 6 |
| GO:0010885 | regulation of cholesterol storage | 4/588 | 14/17913 | 0.0009 | 0.0086 | 4 |
| GO:0010952 | positive regulation of peptidase activity | 15/588 | 180/17913 | 0.0009 | 0.0087 | 15 |
| GO:0031098 | stress-activated protein kinase signaling cascade | 20/588 | 278/17913 | 0.0009 | 0.0087 | 20 |
| GO:0002064 | epithelial cell development | 16/588 | 199/17913 | 0.0009 | 0.0087 | 16 |
| GO:0032648 | regulation of interferon-beta production | 7/588 | 48/17913 | 0.0009 | 0.0087 | 7 |
| GO:0051972 | regulation of telomerase activity | 7/588 | 48/17913 | 0.0009 | 0.0087 | 7 |
| GO:0061647 | histone H3-K9 modification | 7/588 | 48/17913 | 0.0009 | 0.0087 | 7 |
| GO:1903727 | positive regulation of phospholipid metabolic process | 7/588 | 48/17913 | 0.0009 | 0.0087 | 7 |
| GO:0042542 | response to hydrogen peroxide | 13/588 | 144/17913 | 0.0009 | 0.0089 | 13 |
| GO:0098609 | cell-cell adhesion | 42/588 | 771/17913 | 0.0009 | 0.0089 | 42 |
| GO:0009260 | ribonucleotide biosynthetic process | 20/588 | 279/17913 | 0.0009 | 0.0090 | 20 |
| GO:0060148 | positive regulation of posttranscriptional gene silencing | 5/588 | 24/17913 | 0.0009 | 0.0090 | 5 |
| GO:0006164 | purine nucleotide biosynthetic process | 20/588 | 280/17913 | 0.0010 | 0.0094 | 20 |
| GO:0002262 | myeloid cell homeostasis | 13/588 | 145/17913 | 0.0010 | 0.0094 | 13 |
| GO:2001020 | regulation of response to DNA damage stimulus | 16/588 | 201/17913 | 0.0010 | 0.0095 | 16 |
| GO:0043901 | negative regulation of multi-organism process | 15/588 | 182/17913 | 0.0010 | 0.0095 | 15 |
| GO:1903708 | positive regulation of hemopoiesis | 15/588 | 182/17913 | 0.0010 | 0.0095 | 15 |
| GO:0033674 | positive regulation of kinase activity | 32/588 | 541/17913 | 0.0010 | 0.0095 | 32 |
| GO:0031571 | mitotic G1 DNA damage checkpoint | 8/588 | 63/17913 | 0.0010 | 0.0095 | 8 |
| GO:0036498 | IRE1-mediated unfolded protein response | 8/588 | 63/17913 | 0.0010 | 0.0095 | 8 |
| GO:0044819 | mitotic G1/S transition checkpoint | 8/588 | 63/17913 | 0.0010 | 0.0095 | 8 |
| GO:0007229 | integrin-mediated signaling pathway | 10/588 | 94/17913 | 0.0010 | 0.0095 | 10 |
| GO:1990823 | response to leukemia inhibitory factor | 10/588 | 94/17913 | 0.0010 | 0.0095 | 10 |
| GO:1990830 | cellular response to leukemia inhibitory factor | 10/588 | 94/17913 | 0.0010 | 0.0095 | 10 |
| GO:0051973 | positive regulation of telomerase activity | 6/588 | 36/17913 | 0.0010 | 0.0095 | 6 |
| GO:0097237 | cellular response to toxic substance | 18/588 | 241/17913 | 0.0010 | 0.0097 | 18 |
| GO:1904019 | epithelial cell apoptotic process | 11/588 | 111/17913 | 0.0011 | 0.0098 | 11 |
| GO:0043254 | regulation of protein complex assembly | 26/588 | 409/17913 | 0.0011 | 0.0099 | 26 |
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0002366 | leukocyte activation involved in immune response | 59/300 | 684/17913 | 0.0000 | 0.0000 | 59 |
| GO:0002263 | cell activation involved in immune response | 59/300 | 688/17913 | 0.0000 | 0.0000 | 59 |
| GO:0002274 | myeloid leukocyte activation | 56/300 | 652/17913 | 0.0000 | 0.0000 | 56 |
| GO:0036230 | granulocyte activation | 48/300 | 506/17913 | 0.0000 | 0.0000 | 48 |
| GO:0042119 | neutrophil activation | 47/300 | 499/17913 | 0.0000 | 0.0000 | 47 |
| GO:0006887 | exocytosis | 61/300 | 862/17913 | 0.0000 | 0.0000 | 61 |
| GO:0043299 | leukocyte degranulation | 48/300 | 532/17913 | 0.0000 | 0.0000 | 48 |
| GO:0043312 | neutrophil degranulation | 45/300 | 485/17913 | 0.0000 | 0.0000 | 45 |
| GO:0045055 | regulated exocytosis | 56/300 | 768/17913 | 0.0000 | 0.0000 | 56 |
| GO:0002283 | neutrophil activation involved in immune response | 45/300 | 488/17913 | 0.0000 | 0.0000 | 45 |
| GO:0002275 | myeloid cell activation involved in immune response | 47/300 | 542/17913 | 0.0000 | 0.0000 | 47 |
| GO:0002446 | neutrophil mediated immunity | 45/300 | 499/17913 | 0.0000 | 0.0000 | 45 |
| GO:0002444 | myeloid leukocyte mediated immunity | 47/300 | 549/17913 | 0.0000 | 0.0000 | 47 |
| GO:0002443 | leukocyte mediated immunity | 55/300 | 814/17913 | 0.0000 | 0.0000 | 55 |
| GO:0019221 | cytokine-mediated signaling pathway | 46/300 | 764/17913 | 0.0000 | 0.0000 | 46 |
| GO:0097190 | apoptotic signaling pathway | 37/300 | 579/17913 | 0.0000 | 0.0000 | 37 |
| GO:0050865 | regulation of cell activation | 34/300 | 535/17913 | 0.0000 | 0.0000 | 34 |
| GO:2001233 | regulation of apoptotic signaling pathway | 29/300 | 397/17913 | 0.0000 | 0.0000 | 29 |
| GO:0043066 | negative regulation of apoptotic process | 45/300 | 894/17913 | 0.0000 | 0.0000 | 45 |
| GO:0043069 | negative regulation of programmed cell death | 45/300 | 916/17913 | 0.0000 | 0.0000 | 45 |
| GO:0001816 | cytokine production | 40/300 | 765/17913 | 0.0000 | 0.0000 | 40 |
| GO:0002694 | regulation of leukocyte activation | 31/300 | 492/17913 | 0.0000 | 0.0000 | 31 |
| GO:0002520 | immune system development | 44/300 | 938/17913 | 0.0000 | 0.0000 | 44 |
| GO:0014070 | response to organic cyclic compound | 42/300 | 879/17913 | 0.0000 | 0.0000 | 42 |
| GO:0050867 | positive regulation of cell activation | 24/300 | 319/17913 | 0.0000 | 0.0000 | 24 |
| GO:0032870 | cellular response to hormone stimulus | 35/300 | 647/17913 | 0.0000 | 0.0000 | 35 |
| GO:0048534 | hematopoietic or lymphoid organ development | 42/300 | 890/17913 | 0.0000 | 0.0000 | 42 |
| GO:0001817 | regulation of cytokine production | 36/300 | 698/17913 | 0.0000 | 0.0000 | 36 |
| GO:0030097 | hemopoiesis | 40/300 | 847/17913 | 0.0000 | 0.0000 | 40 |
| GO:0010942 | positive regulation of cell death | 36/300 | 710/17913 | 0.0000 | 0.0000 | 36 |
| GO:0019725 | cellular homeostasis | 39/300 | 814/17913 | 0.0000 | 0.0000 | 39 |
| GO:0001818 | negative regulation of cytokine production | 22/300 | 290/17913 | 0.0000 | 0.0000 | 22 |
| GO:0043065 | positive regulation of apoptotic process | 34/300 | 652/17913 | 0.0000 | 0.0000 | 34 |
| GO:0010035 | response to inorganic substance | 30/300 | 528/17913 | 0.0000 | 0.0000 | 30 |
| GO:0043068 | positive regulation of programmed cell death | 34/300 | 660/17913 | 0.0000 | 0.0000 | 34 |
| GO:0002285 | lymphocyte activation involved in immune response | 16/300 | 158/17913 | 0.0000 | 0.0000 | 16 |
| GO:0009725 | response to hormone | 41/300 | 920/17913 | 0.0000 | 0.0000 | 41 |
| GO:0002696 | positive regulation of leukocyte activation | 22/300 | 305/17913 | 0.0000 | 0.0000 | 22 |
| GO:0044403 | symbiont process | 40/300 | 884/17913 | 0.0000 | 0.0000 | 40 |
| GO:0042493 | response to drug | 42/300 | 958/17913 | 0.0000 | 0.0000 | 42 |
| GO:0002700 | regulation of production of molecular mediator of immune response | 15/300 | 138/17913 | 0.0000 | 0.0000 | 15 |
| GO:0044419 | interspecies interaction between organisms | 41/300 | 928/17913 | 0.0000 | 0.0000 | 41 |
| GO:0046916 | cellular transition metal ion homeostasis | 12/300 | 83/17913 | 0.0000 | 0.0000 | 12 |
| GO:0030003 | cellular cation homeostasis | 29/300 | 518/17913 | 0.0000 | 0.0000 | 29 |
| GO:0070997 | neuron death | 23/300 | 347/17913 | 0.0000 | 0.0000 | 23 |
| GO:0002440 | production of molecular mediator of immune response | 17/300 | 191/17913 | 0.0000 | 0.0000 | 17 |
| GO:0006873 | cellular ion homeostasis | 29/300 | 531/17913 | 0.0000 | 0.0000 | 29 |
| GO:0046649 | lymphocyte activation | 32/300 | 630/17913 | 0.0000 | 0.0000 | 32 |
| GO:0000165 | MAPK cascade | 39/300 | 882/17913 | 0.0000 | 0.0000 | 39 |
| GO:0023014 | signal transduction by protein phosphorylation | 39/300 | 886/17913 | 0.0000 | 0.0000 | 39 |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 18/300 | 223/17913 | 0.0000 | 0.0000 | 18 |
| GO:0002521 | leukocyte differentiation | 27/300 | 485/17913 | 0.0000 | 0.0000 | 27 |
| GO:0010038 | response to metal ion | 22/300 | 335/17913 | 0.0000 | 0.0000 | 22 |
| GO:0051050 | positive regulation of transport | 40/300 | 942/17913 | 0.0000 | 0.0000 | 40 |
| GO:0055080 | cation homeostasis | 30/300 | 588/17913 | 0.0000 | 0.0000 | 30 |
| GO:0040007 | growth | 40/300 | 948/17913 | 0.0000 | 0.0000 | 40 |
| GO:0030155 | regulation of cell adhesion | 32/300 | 659/17913 | 0.0000 | 0.0000 | 32 |
| GO:1901214 | regulation of neuron death | 21/300 | 313/17913 | 0.0000 | 0.0000 | 21 |
| GO:0051249 | regulation of lymphocyte activation | 24/300 | 401/17913 | 0.0000 | 0.0000 | 24 |
| GO:0055082 | cellular chemical homeostasis | 32/300 | 666/17913 | 0.0000 | 0.0000 | 32 |
| GO:0050778 | positive regulation of immune response | 36/300 | 809/17913 | 0.0000 | 0.0000 | 36 |
| GO:1903706 | regulation of hemopoiesis | 26/300 | 468/17913 | 0.0000 | 0.0000 | 26 |
| GO:0098771 | inorganic ion homeostasis | 30/300 | 600/17913 | 0.0000 | 0.0000 | 30 |
| GO:0007568 | aging | 21/300 | 318/17913 | 0.0000 | 0.0000 | 21 |
| GO:1903047 | mitotic cell cycle process | 36/300 | 816/17913 | 0.0000 | 0.0000 | 36 |
| GO:0030099 | myeloid cell differentiation | 24/300 | 411/17913 | 0.0000 | 0.0000 | 24 |
| GO:0010243 | response to organonitrogen compound | 39/300 | 932/17913 | 0.0000 | 0.0000 | 39 |
| GO:0000278 | mitotic cell cycle | 39/300 | 934/17913 | 0.0000 | 0.0000 | 39 |
| GO:0016032 | viral process | 36/300 | 822/17913 | 0.0000 | 0.0000 | 36 |
| GO:0007584 | response to nutrient | 17/300 | 215/17913 | 0.0000 | 0.0000 | 17 |
| GO:0051186 | cofactor metabolic process | 28/300 | 543/17913 | 0.0000 | 0.0000 | 28 |
| GO:0007159 | leukocyte cell-cell adhesion | 21/300 | 328/17913 | 0.0000 | 0.0000 | 21 |
| GO:0055076 | transition metal ion homeostasis | 12/300 | 105/17913 | 0.0000 | 0.0000 | 12 |
| GO:0002576 | platelet degranulation | 13/300 | 128/17913 | 0.0000 | 0.0000 | 13 |
| GO:0033993 | response to lipid | 37/300 | 884/17913 | 0.0000 | 0.0000 | 37 |
| GO:0051098 | regulation of binding | 22/300 | 368/17913 | 0.0000 | 0.0000 | 22 |
| GO:0071222 | cellular response to lipopolysaccharide | 15/300 | 176/17913 | 0.0000 | 0.0000 | 15 |
| GO:0050801 | ion homeostasis | 31/300 | 669/17913 | 0.0000 | 0.0000 | 31 |
| GO:0050900 | leukocyte migration | 25/300 | 467/17913 | 0.0000 | 0.0000 | 25 |
| GO:0071219 | cellular response to molecule of bacterial origin | 15/300 | 183/17913 | 0.0000 | 0.0000 | 15 |
| GO:0002683 | negative regulation of immune system process | 24/300 | 451/17913 | 0.0000 | 0.0000 | 24 |
| GO:0007346 | regulation of mitotic cell cycle | 29/300 | 622/17913 | 0.0000 | 0.0000 | 29 |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 32/300 | 735/17913 | 0.0000 | 0.0000 | 32 |
| GO:1905477 | positive regulation of protein localization to membrane | 12/300 | 120/17913 | 0.0000 | 0.0000 | 12 |
| GO:0002637 | regulation of immunoglobulin production | 9/300 | 62/17913 | 0.0000 | 0.0000 | 9 |
| GO:0008284 | positive regulation of cell proliferation | 37/300 | 931/17913 | 0.0000 | 0.0000 | 37 |
| GO:0040008 | regulation of growth | 30/300 | 668/17913 | 0.0000 | 0.0000 | 30 |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 23/300 | 428/17913 | 0.0000 | 0.0000 | 23 |
| GO:0045087 | innate immune response | 36/300 | 893/17913 | 0.0000 | 0.0000 | 36 |
| GO:2000379 | positive regulation of reactive oxygen species metabolic process | 11/300 | 101/17913 | 0.0000 | 0.0001 | 11 |
| GO:0055094 | response to lipoprotein particle | 7/300 | 33/17913 | 0.0000 | 0.0001 | 7 |
| GO:0097193 | intrinsic apoptotic signaling pathway | 18/300 | 277/17913 | 0.0000 | 0.0001 | 18 |
| GO:0044772 | mitotic cell cycle phase transition | 27/300 | 565/17913 | 0.0000 | 0.0001 | 27 |
| GO:0055065 | metal ion homeostasis | 26/300 | 531/17913 | 0.0000 | 0.0001 | 26 |
| GO:2000116 | regulation of cysteine-type endopeptidase activity | 16/300 | 222/17913 | 0.0000 | 0.0001 | 16 |
| GO:1901987 | regulation of cell cycle phase transition | 24/300 | 464/17913 | 0.0000 | 0.0001 | 24 |
| GO:0009991 | response to extracellular stimulus | 25/300 | 498/17913 | 0.0000 | 0.0001 | 25 |
| GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 15/300 | 196/17913 | 0.0000 | 0.0001 | 15 |
| GO:0006954 | inflammatory response | 33/300 | 784/17913 | 0.0000 | 0.0001 | 33 |
| GO:0045637 | regulation of myeloid cell differentiation | 17/300 | 250/17913 | 0.0000 | 0.0001 | 17 |
| GO:0010507 | negative regulation of autophagy | 10/300 | 83/17913 | 0.0000 | 0.0001 | 10 |
| GO:0006875 | cellular metal ion homeostasis | 24/300 | 467/17913 | 0.0000 | 0.0001 | 24 |
| GO:0043302 | positive regulation of leukocyte degranulation | 6/300 | 22/17913 | 0.0000 | 0.0001 | 6 |
| GO:0051338 | regulation of transferase activity | 36/300 | 903/17913 | 0.0000 | 0.0001 | 36 |
| GO:0002699 | positive regulation of immune effector process | 15/300 | 198/17913 | 0.0000 | 0.0001 | 15 |
| GO:0044770 | cell cycle phase transition | 28/300 | 609/17913 | 0.0000 | 0.0001 | 28 |
| GO:0006914 | autophagy | 24/300 | 471/17913 | 0.0000 | 0.0001 | 24 |
| GO:0061919 | process utilizing autophagic mechanism | 24/300 | 471/17913 | 0.0000 | 0.0001 | 24 |
| GO:0071402 | cellular response to lipoprotein particle stimulus | 7/300 | 35/17913 | 0.0000 | 0.0001 | 7 |
| GO:0002573 | myeloid leukocyte differentiation | 15/300 | 201/17913 | 0.0000 | 0.0001 | 15 |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 13/300 | 151/17913 | 0.0000 | 0.0001 | 13 |
| GO:0006979 | response to oxidative stress | 23/300 | 442/17913 | 0.0000 | 0.0001 | 23 |
| GO:0051251 | positive regulation of lymphocyte activation | 17/300 | 258/17913 | 0.0000 | 0.0001 | 17 |
| GO:0009895 | negative regulation of catabolic process | 18/300 | 288/17913 | 0.0000 | 0.0001 | 18 |
| GO:0001819 | positive regulation of cytokine production | 23/300 | 446/17913 | 0.0000 | 0.0001 | 23 |
| GO:0071216 | cellular response to biotic stimulus | 15/300 | 206/17913 | 0.0000 | 0.0001 | 15 |
| GO:1900407 | regulation of cellular response to oxidative stress | 10/300 | 88/17913 | 0.0000 | 0.0001 | 10 |
| GO:1901215 | negative regulation of neuron death | 15/300 | 207/17913 | 0.0000 | 0.0001 | 15 |
| GO:0098609 | cell-cell adhesion | 32/300 | 771/17913 | 0.0000 | 0.0001 | 32 |
| GO:1903708 | positive regulation of hemopoiesis | 14/300 | 182/17913 | 0.0000 | 0.0001 | 14 |
| GO:0045785 | positive regulation of cell adhesion | 21/300 | 388/17913 | 0.0000 | 0.0001 | 21 |
| GO:0032496 | response to lipopolysaccharide | 18/300 | 295/17913 | 0.0000 | 0.0001 | 18 |
| GO:0070482 | response to oxygen levels | 21/300 | 389/17913 | 0.0000 | 0.0001 | 21 |
| GO:0034599 | cellular response to oxidative stress | 18/300 | 296/17913 | 0.0000 | 0.0001 | 18 |
| GO:1901652 | response to peptide | 24/300 | 491/17913 | 0.0000 | 0.0001 | 24 |
| GO:0099132 | ATP hydrolysis coupled cation transmembrane transport | 8/300 | 54/17913 | 0.0000 | 0.0001 | 8 |
| GO:0071901 | negative regulation of protein serine/threonine kinase activity | 12/300 | 136/17913 | 0.0000 | 0.0001 | 12 |
| GO:0002685 | regulation of leukocyte migration | 14/300 | 186/17913 | 0.0000 | 0.0001 | 14 |
| GO:0070661 | leukocyte proliferation | 17/300 | 270/17913 | 0.0000 | 0.0001 | 17 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 15/300 | 214/17913 | 0.0000 | 0.0001 | 15 |
| GO:0051707 | response to other organism | 35/300 | 903/17913 | 0.0000 | 0.0001 | 35 |
| GO:0043207 | response to external biotic stimulus | 35/300 | 905/17913 | 0.0000 | 0.0001 | 35 |
| GO:1902175 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | 6/300 | 26/17913 | 0.0000 | 0.0001 | 6 |
| GO:0002764 | immune response-regulating signaling pathway | 27/300 | 603/17913 | 0.0000 | 0.0001 | 27 |
| GO:0031330 | negative regulation of cellular catabolic process | 16/300 | 244/17913 | 0.0000 | 0.0001 | 16 |
| GO:0071407 | cellular response to organic cyclic compound | 25/300 | 533/17913 | 0.0000 | 0.0001 | 25 |
| GO:0030316 | osteoclast differentiation | 10/300 | 94/17913 | 0.0000 | 0.0001 | 10 |
| GO:0006826 | iron ion transport | 8/300 | 56/17913 | 0.0000 | 0.0001 | 8 |
| GO:0032943 | mononuclear cell proliferation | 16/300 | 246/17913 | 0.0000 | 0.0001 | 16 |
| GO:0043086 | negative regulation of catalytic activity | 31/300 | 757/17913 | 0.0000 | 0.0001 | 31 |
| GO:0052548 | regulation of endopeptidase activity | 20/300 | 370/17913 | 0.0000 | 0.0001 | 20 |
| GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress | 7/300 | 41/17913 | 0.0000 | 0.0002 | 7 |
| GO:0071396 | cellular response to lipid | 26/300 | 576/17913 | 0.0000 | 0.0002 | 26 |
| GO:0043434 | response to peptide hormone | 21/300 | 404/17913 | 0.0000 | 0.0002 | 21 |
| GO:0002237 | response to molecule of bacterial origin | 18/300 | 309/17913 | 0.0000 | 0.0002 | 18 |
| GO:1902882 | regulation of response to oxidative stress | 10/300 | 97/17913 | 0.0000 | 0.0002 | 10 |
| GO:0045089 | positive regulation of innate immune response | 20/300 | 373/17913 | 0.0000 | 0.0002 | 20 |
| GO:1902107 | positive regulation of leukocyte differentiation | 12/300 | 143/17913 | 0.0000 | 0.0002 | 12 |
| GO:0045088 | regulation of innate immune response | 22/300 | 440/17913 | 0.0000 | 0.0002 | 22 |
| GO:0002697 | regulation of immune effector process | 22/300 | 441/17913 | 0.0000 | 0.0002 | 22 |
| GO:0002377 | immunoglobulin production | 10/300 | 98/17913 | 0.0000 | 0.0002 | 10 |
| GO:0034394 | protein localization to cell surface | 8/300 | 59/17913 | 0.0000 | 0.0002 | 8 |
| GO:0010506 | regulation of autophagy | 18/300 | 314/17913 | 0.0000 | 0.0002 | 18 |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 23/300 | 479/17913 | 0.0000 | 0.0002 | 23 |
| GO:0043300 | regulation of leukocyte degranulation | 7/300 | 43/17913 | 0.0000 | 0.0002 | 7 |
| GO:0032930 | positive regulation of superoxide anion generation | 5/300 | 17/17913 | 0.0000 | 0.0002 | 5 |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 10/300 | 100/17913 | 0.0000 | 0.0002 | 10 |
| GO:0009611 | response to wounding | 28/300 | 665/17913 | 0.0000 | 0.0002 | 28 |
| GO:0009607 | response to biotic stimulus | 35/300 | 938/17913 | 0.0000 | 0.0002 | 35 |
| GO:0031589 | cell-substrate adhesion | 18/300 | 322/17913 | 0.0000 | 0.0002 | 18 |
| GO:0071887 | leukocyte apoptotic process | 10/300 | 103/17913 | 0.0000 | 0.0002 | 10 |
| GO:0043062 | extracellular structure organization | 20/300 | 387/17913 | 0.0000 | 0.0003 | 20 |
| GO:0045921 | positive regulation of exocytosis | 9/300 | 82/17913 | 0.0000 | 0.0003 | 9 |
| GO:2001235 | positive regulation of apoptotic signaling pathway | 13/300 | 178/17913 | 0.0000 | 0.0003 | 13 |
| GO:0006897 | endocytosis | 28/300 | 675/17913 | 0.0000 | 0.0003 | 28 |
| GO:0031400 | negative regulation of protein modification process | 26/300 | 602/17913 | 0.0000 | 0.0003 | 26 |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 17/300 | 295/17913 | 0.0000 | 0.0003 | 17 |
| GO:0009894 | regulation of catabolic process | 34/300 | 916/17913 | 0.0000 | 0.0003 | 34 |
| GO:0051090 | regulation of DNA-binding transcription factor activity | 21/300 | 429/17913 | 0.0000 | 0.0003 | 21 |
| GO:0051402 | neuron apoptotic process | 15/300 | 238/17913 | 0.0000 | 0.0003 | 15 |
| GO:0050878 | regulation of body fluid levels | 23/300 | 499/17913 | 0.0000 | 0.0003 | 23 |
| GO:0043523 | regulation of neuron apoptotic process | 14/300 | 210/17913 | 0.0000 | 0.0003 | 14 |
| GO:0072593 | reactive oxygen species metabolic process | 16/300 | 269/17913 | 0.0000 | 0.0003 | 16 |
| GO:0016049 | cell growth | 22/300 | 466/17913 | 0.0000 | 0.0003 | 22 |
| GO:0031667 | response to nutrient levels | 22/300 | 466/17913 | 0.0000 | 0.0003 | 22 |
| GO:0052547 | regulation of peptidase activity | 20/300 | 398/17913 | 0.0000 | 0.0003 | 20 |
| GO:0051051 | negative regulation of transport | 23/300 | 502/17913 | 0.0000 | 0.0003 | 23 |
| GO:0010564 | regulation of cell cycle process | 30/300 | 764/17913 | 0.0000 | 0.0004 | 30 |
| GO:1903307 | positive regulation of regulated secretory pathway | 7/300 | 48/17913 | 0.0000 | 0.0004 | 7 |
| GO:0002703 | regulation of leukocyte mediated immunity | 13/300 | 185/17913 | 0.0000 | 0.0004 | 13 |
| GO:0097191 | extrinsic apoptotic signaling pathway | 14/300 | 213/17913 | 0.0000 | 0.0004 | 14 |
| GO:0033002 | muscle cell proliferation | 15/300 | 243/17913 | 0.0000 | 0.0004 | 15 |
| GO:0070663 | regulation of leukocyte proliferation | 14/300 | 214/17913 | 0.0000 | 0.0004 | 14 |
| GO:0009117 | nucleotide metabolic process | 27/300 | 654/17913 | 0.0000 | 0.0004 | 27 |
| GO:0046651 | lymphocyte proliferation | 15/300 | 244/17913 | 0.0000 | 0.0004 | 15 |
| GO:0042113 | B cell activation | 14/300 | 215/17913 | 0.0000 | 0.0004 | 14 |
| GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 11/300 | 135/17913 | 0.0000 | 0.0004 | 11 |
| GO:1902532 | negative regulation of intracellular signal transduction | 24/300 | 550/17913 | 0.0000 | 0.0005 | 24 |
| GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 12/300 | 163/17913 | 0.0000 | 0.0005 | 12 |
| GO:0006753 | nucleoside phosphate metabolic process | 27/300 | 663/17913 | 0.0000 | 0.0005 | 27 |
| GO:0032928 | regulation of superoxide anion generation | 5/300 | 21/17913 | 0.0000 | 0.0005 | 5 |
| GO:0070848 | response to growth factor | 28/300 | 704/17913 | 0.0000 | 0.0005 | 28 |
| GO:0002701 | negative regulation of production of molecular mediator of immune response | 6/300 | 35/17913 | 0.0000 | 0.0005 | 6 |
| GO:0090322 | regulation of superoxide metabolic process | 6/300 | 35/17913 | 0.0000 | 0.0005 | 6 |
| GO:0051272 | positive regulation of cellular component movement | 24/300 | 555/17913 | 0.0000 | 0.0005 | 24 |
| GO:0022409 | positive regulation of cell-cell adhesion | 15/300 | 251/17913 | 0.0000 | 0.0005 | 15 |
| GO:0045628 | regulation of T-helper 2 cell differentiation | 4/300 | 11/17913 | 0.0000 | 0.0005 | 4 |
| GO:0036473 | cell death in response to oxidative stress | 9/300 | 92/17913 | 0.0000 | 0.0005 | 9 |
| GO:0002312 | B cell activation involved in immune response | 8/300 | 71/17913 | 0.0000 | 0.0005 | 8 |
| GO:0042100 | B cell proliferation | 8/300 | 71/17913 | 0.0000 | 0.0005 | 8 |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 15/300 | 253/17913 | 0.0000 | 0.0006 | 15 |
| GO:0002702 | positive regulation of production of molecular mediator of immune response | 9/300 | 93/17913 | 0.0000 | 0.0006 | 9 |
| GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 14/300 | 224/17913 | 0.0000 | 0.0006 | 14 |
| GO:0098657 | import into cell | 29/300 | 751/17913 | 0.0000 | 0.0006 | 29 |
| GO:0010742 | macrophage derived foam cell differentiation | 6/300 | 36/17913 | 0.0000 | 0.0006 | 6 |
| GO:0015682 | ferric iron transport | 6/300 | 36/17913 | 0.0000 | 0.0006 | 6 |
| GO:0033572 | transferrin transport | 6/300 | 36/17913 | 0.0000 | 0.0006 | 6 |
| GO:0072512 | trivalent inorganic cation transport | 6/300 | 36/17913 | 0.0000 | 0.0006 | 6 |
| GO:0090077 | foam cell differentiation | 6/300 | 36/17913 | 0.0000 | 0.0006 | 6 |
| GO:0002705 | positive regulation of leukocyte mediated immunity | 10/300 | 117/17913 | 0.0000 | 0.0006 | 10 |
| GO:0002761 | regulation of myeloid leukocyte differentiation | 10/300 | 117/17913 | 0.0000 | 0.0006 | 10 |
| GO:0002218 | activation of innate immune response | 17/300 | 319/17913 | 0.0000 | 0.0006 | 17 |
| GO:0050870 | positive regulation of T cell activation | 13/300 | 198/17913 | 0.0000 | 0.0006 | 13 |
| GO:0051046 | regulation of secretion | 29/300 | 757/17913 | 0.0000 | 0.0006 | 29 |
| GO:0002757 | immune response-activating signal transduction | 24/300 | 567/17913 | 0.0000 | 0.0007 | 24 |
| GO:0022407 | regulation of cell-cell adhesion | 19/300 | 389/17913 | 0.0000 | 0.0007 | 19 |
| GO:0030001 | metal ion transport | 30/300 | 800/17913 | 0.0000 | 0.0007 | 30 |
| GO:0071404 | cellular response to low-density lipoprotein particle stimulus | 5/300 | 23/17913 | 0.0000 | 0.0007 | 5 |
| GO:0032944 | regulation of mononuclear cell proliferation | 13/300 | 200/17913 | 0.0000 | 0.0007 | 13 |
| GO:0048660 | regulation of smooth muscle cell proliferation | 12/300 | 172/17913 | 0.0000 | 0.0007 | 12 |
| GO:0042089 | cytokine biosynthetic process | 10/300 | 120/17913 | 0.0000 | 0.0007 | 10 |
| GO:0051101 | regulation of DNA binding | 10/300 | 120/17913 | 0.0000 | 0.0007 | 10 |
| GO:0071888 | macrophage apoptotic process | 4/300 | 12/17913 | 0.0000 | 0.0007 | 4 |
| GO:2000145 | regulation of cell motility | 34/300 | 966/17913 | 0.0000 | 0.0007 | 34 |
| GO:1903201 | regulation of oxidative stress-induced cell death | 8/300 | 75/17913 | 0.0000 | 0.0007 | 8 |
| GO:0031347 | regulation of defense response | 32/300 | 885/17913 | 0.0000 | 0.0007 | 32 |
| GO:0042107 | cytokine metabolic process | 10/300 | 121/17913 | 0.0000 | 0.0007 | 10 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 34/300 | 968/17913 | 0.0000 | 0.0007 | 34 |
| GO:0048659 | smooth muscle cell proliferation | 12/300 | 174/17913 | 0.0000 | 0.0007 | 12 |
| GO:0043903 | regulation of symbiosis, encompassing mutualism through parasitism | 14/300 | 232/17913 | 0.0000 | 0.0008 | 14 |
| GO:0043408 | regulation of MAPK cascade | 27/300 | 689/17913 | 0.0000 | 0.0008 | 27 |
| GO:0043549 | regulation of kinase activity | 30/300 | 808/17913 | 0.0000 | 0.0008 | 30 |
| GO:0071375 | cellular response to peptide hormone stimulus | 16/300 | 297/17913 | 0.0000 | 0.0008 | 16 |
| GO:0006879 | cellular iron ion homeostasis | 7/300 | 57/17913 | 0.0000 | 0.0009 | 7 |
| GO:0045859 | regulation of protein kinase activity | 28/300 | 733/17913 | 0.0000 | 0.0009 | 28 |
| GO:0043112 | receptor metabolic process | 12/300 | 177/17913 | 0.0000 | 0.0009 | 12 |
| GO:1901653 | cellular response to peptide | 18/300 | 364/17913 | 0.0000 | 0.0009 | 18 |
| GO:0002758 | innate immune response-activating signal transduction | 16/300 | 298/17913 | 0.0000 | 0.0009 | 16 |
| GO:0002819 | regulation of adaptive immune response | 11/300 | 150/17913 | 0.0000 | 0.0009 | 11 |
| GO:0010959 | regulation of metal ion transport | 18/300 | 365/17913 | 0.0000 | 0.0009 | 18 |
| GO:0036293 | response to decreased oxygen levels | 18/300 | 365/17913 | 0.0000 | 0.0009 | 18 |
| GO:1902105 | regulation of leukocyte differentiation | 15/300 | 267/17913 | 0.0000 | 0.0009 | 15 |
| GO:0051170 | import into nucleus | 10/300 | 125/17913 | 0.0000 | 0.0009 | 10 |
| GO:0006732 | coenzyme metabolic process | 18/300 | 366/17913 | 0.0000 | 0.0009 | 18 |
| GO:0048661 | positive regulation of smooth muscle cell proliferation | 9/300 | 101/17913 | 0.0000 | 0.0009 | 9 |
| GO:1903827 | regulation of cellular protein localization | 22/300 | 509/17913 | 0.0001 | 0.0009 | 22 |
| GO:0002719 | negative regulation of cytokine production involved in immune response | 5/300 | 25/17913 | 0.0001 | 0.0009 | 5 |
| GO:0015991 | ATP hydrolysis coupled proton transport | 5/300 | 25/17913 | 0.0001 | 0.0009 | 5 |
| GO:0030198 | extracellular matrix organization | 17/300 | 334/17913 | 0.0001 | 0.0009 | 17 |
| GO:0055086 | nucleobase-containing small molecule metabolic process | 28/300 | 740/17913 | 0.0001 | 0.0009 | 28 |
| GO:0031623 | receptor internalization | 9/300 | 102/17913 | 0.0001 | 0.0010 | 9 |
| GO:0060341 | regulation of cellular localization | 31/300 | 863/17913 | 0.0001 | 0.0010 | 31 |
| GO:0071346 | cellular response to interferon-gamma | 11/300 | 153/17913 | 0.0001 | 0.0010 | 11 |
| GO:0031349 | positive regulation of defense response | 22/300 | 512/17913 | 0.0001 | 0.0010 | 22 |
| GO:0007599 | hemostasis | 17/300 | 336/17913 | 0.0001 | 0.0010 | 17 |
| GO:0051403 | stress-activated MAPK cascade | 15/300 | 271/17913 | 0.0001 | 0.0010 | 15 |
| GO:1903530 | regulation of secretion by cell | 27/300 | 703/17913 | 0.0001 | 0.0010 | 27 |
| GO:1905475 | regulation of protein localization to membrane | 12/300 | 181/17913 | 0.0001 | 0.0010 | 12 |
| GO:0030334 | regulation of cell migration | 32/300 | 906/17913 | 0.0001 | 0.0010 | 32 |
| GO:0009617 | response to bacterium | 24/300 | 588/17913 | 0.0001 | 0.0010 | 24 |
| GO:0043536 | positive regulation of blood vessel endothelial cell migration | 8/300 | 80/17913 | 0.0001 | 0.0010 | 8 |
| GO:0006911 | phagocytosis, engulfment | 6/300 | 41/17913 | 0.0001 | 0.0010 | 6 |
| GO:0051348 | negative regulation of transferase activity | 15/300 | 272/17913 | 0.0001 | 0.0010 | 15 |
| GO:0006606 | protein import into nucleus | 9/300 | 103/17913 | 0.0001 | 0.0010 | 9 |
| GO:0048872 | homeostasis of number of cells | 14/300 | 241/17913 | 0.0001 | 0.0010 | 14 |
| GO:0043534 | blood vessel endothelial cell migration | 12/300 | 182/17913 | 0.0001 | 0.0010 | 12 |
| GO:0042110 | T cell activation | 20/300 | 443/17913 | 0.0001 | 0.0010 | 20 |
| GO:0030335 | positive regulation of cell migration | 22/300 | 516/17913 | 0.0001 | 0.0010 | 22 |
| GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 7/300 | 60/17913 | 0.0001 | 0.0010 | 7 |
| GO:0016444 | somatic cell DNA recombination | 7/300 | 60/17913 | 0.0001 | 0.0010 | 7 |
| GO:0060759 | regulation of response to cytokine stimulus | 12/300 | 183/17913 | 0.0001 | 0.0010 | 12 |
| GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient | 5/300 | 26/17913 | 0.0001 | 0.0010 | 5 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 26/300 | 669/17913 | 0.0001 | 0.0010 | 26 |
| GO:0050863 | regulation of T cell activation | 16/300 | 307/17913 | 0.0001 | 0.0011 | 16 |
| GO:0033673 | negative regulation of kinase activity | 14/300 | 244/17913 | 0.0001 | 0.0011 | 14 |
| GO:0045926 | negative regulation of growth | 14/300 | 244/17913 | 0.0001 | 0.0011 | 14 |
| GO:0051924 | regulation of calcium ion transport | 14/300 | 244/17913 | 0.0001 | 0.0011 | 14 |
| GO:0006974 | cellular response to DNA damage stimulus | 29/300 | 791/17913 | 0.0001 | 0.0011 | 29 |
| GO:0002523 | leukocyte migration involved in inflammatory response | 4/300 | 14/17913 | 0.0001 | 0.0011 | 4 |
| GO:0045064 | T-helper 2 cell differentiation | 4/300 | 14/17913 | 0.0001 | 0.0011 | 4 |
| GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 12/300 | 185/17913 | 0.0001 | 0.0011 | 12 |
| GO:0080135 | regulation of cellular response to stress | 27/300 | 713/17913 | 0.0001 | 0.0011 | 27 |
| GO:0071363 | cellular response to growth factor stimulus | 26/300 | 674/17913 | 0.0001 | 0.0011 | 26 |
| GO:0031098 | stress-activated protein kinase signaling cascade | 15/300 | 278/17913 | 0.0001 | 0.0012 | 15 |
| GO:0002718 | regulation of cytokine production involved in immune response | 8/300 | 83/17913 | 0.0001 | 0.0012 | 8 |
| GO:0099131 | ATP hydrolysis coupled ion transmembrane transport | 5/300 | 27/17913 | 0.0001 | 0.0012 | 5 |
| GO:0070542 | response to fatty acid | 8/300 | 85/17913 | 0.0001 | 0.0014 | 8 |
| GO:0002467 | germinal center formation | 4/300 | 15/17913 | 0.0001 | 0.0014 | 4 |
| GO:0090662 | ATP hydrolysis coupled transmembrane transport | 5/300 | 28/17913 | 0.0001 | 0.0014 | 5 |
| GO:0051100 | negative regulation of binding | 11/300 | 162/17913 | 0.0001 | 0.0014 | 11 |
| GO:0002253 | activation of immune response | 25/300 | 647/17913 | 0.0001 | 0.0015 | 25 |
| GO:0032602 | chemokine production | 8/300 | 86/17913 | 0.0001 | 0.0015 | 8 |
| GO:0048145 | regulation of fibroblast proliferation | 8/300 | 86/17913 | 0.0001 | 0.0015 | 8 |
| GO:0040017 | positive regulation of locomotion | 23/300 | 570/17913 | 0.0001 | 0.0015 | 23 |
| GO:0042035 | regulation of cytokine biosynthetic process | 9/300 | 110/17913 | 0.0001 | 0.0015 | 9 |
| GO:0050864 | regulation of B cell activation | 9/300 | 110/17913 | 0.0001 | 0.0015 | 9 |
| GO:0071675 | regulation of mononuclear cell migration | 6/300 | 45/17913 | 0.0001 | 0.0015 | 6 |
| GO:0006469 | negative regulation of protein kinase activity | 13/300 | 222/17913 | 0.0001 | 0.0015 | 13 |
| GO:0051235 | maintenance of location | 15/300 | 286/17913 | 0.0001 | 0.0015 | 15 |
| GO:0071466 | cellular response to xenobiotic stimulus | 11/300 | 164/17913 | 0.0001 | 0.0015 | 11 |
| GO:0048144 | fibroblast proliferation | 8/300 | 87/17913 | 0.0001 | 0.0016 | 8 |
| GO:0045936 | negative regulation of phosphate metabolic process | 23/300 | 573/17913 | 0.0001 | 0.0016 | 23 |
| GO:0009411 | response to UV | 10/300 | 137/17913 | 0.0001 | 0.0016 | 10 |
| GO:0032880 | regulation of protein localization | 33/300 | 979/17913 | 0.0001 | 0.0016 | 33 |
| GO:0010563 | negative regulation of phosphorus metabolic process | 23/300 | 574/17913 | 0.0001 | 0.0016 | 23 |
| GO:0071241 | cellular response to inorganic substance | 12/300 | 194/17913 | 0.0001 | 0.0016 | 12 |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 12/300 | 194/17913 | 0.0001 | 0.0016 | 12 |
| GO:0044843 | cell cycle G1/S phase transition | 15/300 | 288/17913 | 0.0001 | 0.0016 | 15 |
| GO:0031329 | regulation of cellular catabolic process | 29/300 | 814/17913 | 0.0001 | 0.0016 | 29 |
| GO:0016241 | regulation of macroautophagy | 11/300 | 166/17913 | 0.0001 | 0.0017 | 11 |
| GO:0097067 | cellular response to thyroid hormone stimulus | 4/300 | 16/17913 | 0.0001 | 0.0017 | 4 |
| GO:2000147 | positive regulation of cell motility | 22/300 | 540/17913 | 0.0001 | 0.0017 | 22 |
| GO:0071248 | cellular response to metal ion | 11/300 | 167/17913 | 0.0001 | 0.0017 | 11 |
| GO:0030098 | lymphocyte differentiation | 16/300 | 325/17913 | 0.0001 | 0.0018 | 16 |
| GO:0002200 | somatic diversification of immune receptors | 7/300 | 67/17913 | 0.0001 | 0.0018 | 7 |
| GO:0010743 | regulation of macrophage derived foam cell differentiation | 5/300 | 30/17913 | 0.0001 | 0.0018 | 5 |
| GO:0061082 | myeloid leukocyte cytokine production | 5/300 | 30/17913 | 0.0001 | 0.0018 | 5 |
| GO:1901699 | cellular response to nitrogen compound | 24/300 | 620/17913 | 0.0001 | 0.0018 | 24 |
| GO:0045639 | positive regulation of myeloid cell differentiation | 8/300 | 90/17913 | 0.0001 | 0.0019 | 8 |
| GO:0001934 | positive regulation of protein phosphorylation | 31/300 | 907/17913 | 0.0001 | 0.0019 | 31 |
| GO:0050670 | regulation of lymphocyte proliferation | 12/300 | 199/17913 | 0.0001 | 0.0019 | 12 |
| GO:0000041 | transition metal ion transport | 8/300 | 91/17913 | 0.0001 | 0.0020 | 8 |
| GO:0060333 | interferon-gamma-mediated signaling pathway | 8/300 | 91/17913 | 0.0001 | 0.0020 | 8 |
| GO:0042327 | positive regulation of phosphorylation | 32/300 | 955/17913 | 0.0002 | 0.0021 | 32 |
| GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 4/300 | 17/17913 | 0.0002 | 0.0021 | 4 |
| GO:0007596 | blood coagulation | 16/300 | 331/17913 | 0.0002 | 0.0021 | 16 |
| GO:0042060 | wound healing | 22/300 | 550/17913 | 0.0002 | 0.0021 | 22 |
| GO:0019216 | regulation of lipid metabolic process | 18/300 | 402/17913 | 0.0002 | 0.0022 | 18 |
| GO:1902749 | regulation of cell cycle G2/M phase transition | 12/300 | 202/17913 | 0.0002 | 0.0022 | 12 |
| GO:0006935 | chemotaxis | 22/300 | 551/17913 | 0.0002 | 0.0022 | 22 |
| GO:0016447 | somatic recombination of immunoglobulin gene segments | 6/300 | 49/17913 | 0.0002 | 0.0022 | 6 |
| GO:0034341 | response to interferon-gamma | 11/300 | 173/17913 | 0.0002 | 0.0022 | 11 |
| GO:0051897 | positive regulation of protein kinase B signaling | 11/300 | 173/17913 | 0.0002 | 0.0022 | 11 |
| GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 9/300 | 118/17913 | 0.0002 | 0.0022 | 9 |
| GO:0042330 | taxis | 22/300 | 553/17913 | 0.0002 | 0.0023 | 22 |
| GO:0045597 | positive regulation of cell differentiation | 32/300 | 962/17913 | 0.0002 | 0.0023 | 32 |
| GO:0033028 | myeloid cell apoptotic process | 5/300 | 32/17913 | 0.0002 | 0.0024 | 5 |
| GO:0006259 | DNA metabolic process | 32/300 | 964/17913 | 0.0002 | 0.0024 | 32 |
| GO:0045851 | pH reduction | 6/300 | 50/17913 | 0.0002 | 0.0024 | 6 |
| GO:0099024 | plasma membrane invagination | 6/300 | 50/17913 | 0.0002 | 0.0024 | 6 |
| GO:1905517 | macrophage migration | 6/300 | 50/17913 | 0.0002 | 0.0024 | 6 |
| GO:0007229 | integrin-mediated signaling pathway | 8/300 | 94/17913 | 0.0002 | 0.0024 | 8 |
| GO:0060627 | regulation of vesicle-mediated transport | 20/300 | 480/17913 | 0.0002 | 0.0024 | 20 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 14/300 | 269/17913 | 0.0002 | 0.0024 | 14 |
| GO:0002224 | toll-like receptor signaling pathway | 10/300 | 147/17913 | 0.0002 | 0.0025 | 10 |
| GO:0050817 | coagulation | 16/300 | 337/17913 | 0.0002 | 0.0025 | 16 |
| GO:0033273 | response to vitamin | 8/300 | 95/17913 | 0.0002 | 0.0025 | 8 |
| GO:0009410 | response to xenobiotic stimulus | 14/300 | 270/17913 | 0.0002 | 0.0025 | 14 |
| GO:0006882 | cellular zinc ion homeostasis | 4/300 | 18/17913 | 0.0002 | 0.0025 | 4 |
| GO:1902176 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | 4/300 | 18/17913 | 0.0002 | 0.0025 | 4 |
| GO:0051047 | positive regulation of secretion | 18/300 | 409/17913 | 0.0002 | 0.0025 | 18 |
| GO:0002712 | regulation of B cell mediated immunity | 6/300 | 51/17913 | 0.0002 | 0.0026 | 6 |
| GO:0002889 | regulation of immunoglobulin mediated immune response | 6/300 | 51/17913 | 0.0002 | 0.0026 | 6 |
| GO:0002687 | positive regulation of leukocyte migration | 9/300 | 121/17913 | 0.0002 | 0.0026 | 9 |
| GO:0016242 | negative regulation of macroautophagy | 5/300 | 33/17913 | 0.0002 | 0.0026 | 5 |
| GO:0042554 | superoxide anion generation | 5/300 | 33/17913 | 0.0002 | 0.0026 | 5 |
| GO:0045191 | regulation of isotype switching | 5/300 | 33/17913 | 0.0002 | 0.0026 | 5 |
| GO:0097242 | amyloid-beta clearance | 5/300 | 33/17913 | 0.0002 | 0.0026 | 5 |
| GO:0051169 | nuclear transport | 15/300 | 305/17913 | 0.0002 | 0.0026 | 15 |
| GO:0048545 | response to steroid hormone | 17/300 | 375/17913 | 0.0002 | 0.0026 | 17 |
| GO:0016236 | macroautophagy | 14/300 | 272/17913 | 0.0002 | 0.0026 | 14 |
| GO:0040013 | negative regulation of locomotion | 17/300 | 377/17913 | 0.0002 | 0.0028 | 17 |
| GO:0001909 | leukocyte mediated cytotoxicity | 8/300 | 97/17913 | 0.0002 | 0.0028 | 8 |
| GO:0006909 | phagocytosis | 15/300 | 308/17913 | 0.0002 | 0.0028 | 15 |
| GO:0045930 | negative regulation of mitotic cell cycle | 15/300 | 308/17913 | 0.0002 | 0.0028 | 15 |
| GO:0043542 | endothelial cell migration | 14/300 | 275/17913 | 0.0002 | 0.0029 | 14 |
| GO:0055072 | iron ion homeostasis | 7/300 | 74/17913 | 0.0002 | 0.0029 | 7 |
| GO:0006163 | purine nucleotide metabolic process | 21/300 | 528/17913 | 0.0002 | 0.0029 | 21 |
| GO:0051099 | positive regulation of binding | 11/300 | 181/17913 | 0.0002 | 0.0030 | 11 |
| GO:0070838 | divalent metal ion transport | 19/300 | 454/17913 | 0.0002 | 0.0030 | 19 |
| GO:0005996 | monosaccharide metabolic process | 14/300 | 277/17913 | 0.0003 | 0.0031 | 14 |
| GO:0042326 | negative regulation of phosphorylation | 19/300 | 455/17913 | 0.0003 | 0.0031 | 19 |
| GO:0002763 | positive regulation of myeloid leukocyte differentiation | 6/300 | 54/17913 | 0.0003 | 0.0033 | 6 |
| GO:1903078 | positive regulation of protein localization to plasma membrane | 6/300 | 54/17913 | 0.0003 | 0.0033 | 6 |
| GO:0046822 | regulation of nucleocytoplasmic transport | 8/300 | 100/17913 | 0.0003 | 0.0033 | 8 |
| GO:0072511 | divalent inorganic cation transport | 19/300 | 458/17913 | 0.0003 | 0.0033 | 19 |
| GO:0006164 | purine nucleotide biosynthetic process | 14/300 | 280/17913 | 0.0003 | 0.0034 | 14 |
| GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 10/300 | 155/17913 | 0.0003 | 0.0034 | 10 |
| GO:0002367 | cytokine production involved in immune response | 8/300 | 101/17913 | 0.0003 | 0.0035 | 8 |
| GO:0033194 | response to hydroperoxide | 4/300 | 20/17913 | 0.0003 | 0.0035 | 4 |
| GO:0055069 | zinc ion homeostasis | 4/300 | 20/17913 | 0.0003 | 0.0035 | 4 |
| GO:0071636 | positive regulation of transforming growth factor beta production | 4/300 | 20/17913 | 0.0003 | 0.0035 | 4 |
| GO:0009636 | response to toxic substance | 20/300 | 499/17913 | 0.0003 | 0.0035 | 20 |
| GO:0034109 | homotypic cell-cell adhesion | 7/300 | 77/17913 | 0.0003 | 0.0035 | 7 |
| GO:0016445 | somatic diversification of immunoglobulins | 6/300 | 55/17913 | 0.0003 | 0.0035 | 6 |
| GO:0031663 | lipopolysaccharide-mediated signaling pathway | 6/300 | 55/17913 | 0.0003 | 0.0035 | 6 |
| GO:0042306 | regulation of protein import into nucleus | 6/300 | 55/17913 | 0.0003 | 0.0035 | 6 |
| GO:0008286 | insulin receptor signaling pathway | 9/300 | 128/17913 | 0.0003 | 0.0036 | 9 |
| GO:0032355 | response to estradiol | 9/300 | 128/17913 | 0.0003 | 0.0036 | 9 |
| GO:1905521 | regulation of macrophage migration | 5/300 | 36/17913 | 0.0003 | 0.0036 | 5 |
| GO:1903829 | positive regulation of cellular protein localization | 15/300 | 318/17913 | 0.0003 | 0.0037 | 15 |
| GO:0017157 | regulation of exocytosis | 11/300 | 187/17913 | 0.0003 | 0.0037 | 11 |
| GO:0010595 | positive regulation of endothelial cell migration | 9/300 | 129/17913 | 0.0003 | 0.0037 | 9 |
| GO:0022617 | extracellular matrix disassembly | 7/300 | 78/17913 | 0.0003 | 0.0038 | 7 |
| GO:0001666 | response to hypoxia | 16/300 | 354/17913 | 0.0003 | 0.0038 | 16 |
| GO:0010631 | epithelial cell migration | 16/300 | 354/17913 | 0.0003 | 0.0038 | 16 |
| GO:1903202 | negative regulation of oxidative stress-induced cell death | 6/300 | 56/17913 | 0.0003 | 0.0038 | 6 |
| GO:0043535 | regulation of blood vessel endothelial cell migration | 10/300 | 158/17913 | 0.0003 | 0.0038 | 10 |
| GO:0048524 | positive regulation of viral process | 8/300 | 103/17913 | 0.0003 | 0.0038 | 8 |
| GO:0032868 | response to insulin | 13/300 | 252/17913 | 0.0003 | 0.0039 | 13 |
| GO:0030212 | hyaluronan metabolic process | 5/300 | 37/17913 | 0.0004 | 0.0040 | 5 |
| GO:0032101 | regulation of response to external stimulus | 29/300 | 873/17913 | 0.0004 | 0.0040 | 29 |
| GO:0090132 | epithelium migration | 16/300 | 357/17913 | 0.0004 | 0.0040 | 16 |
| GO:0090087 | regulation of peptide transport | 25/300 | 706/17913 | 0.0004 | 0.0041 | 25 |
| GO:0006925 | inflammatory cell apoptotic process | 4/300 | 21/17913 | 0.0004 | 0.0041 | 4 |
| GO:0046686 | response to cadmium ion | 6/300 | 57/17913 | 0.0004 | 0.0041 | 6 |
| GO:1900408 | negative regulation of cellular response to oxidative stress | 6/300 | 57/17913 | 0.0004 | 0.0041 | 6 |
| GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 6/300 | 57/17913 | 0.0004 | 0.0041 | 6 |
| GO:0006886 | intracellular protein transport | 28/300 | 833/17913 | 0.0004 | 0.0041 | 28 |
| GO:0017144 | drug metabolic process | 27/300 | 792/17913 | 0.0004 | 0.0042 | 27 |
| GO:0071706 | tumor necrosis factor superfamily cytokine production | 10/300 | 161/17913 | 0.0004 | 0.0043 | 10 |
| GO:0001558 | regulation of cell growth | 17/300 | 396/17913 | 0.0004 | 0.0043 | 17 |
| GO:0009165 | nucleotide biosynthetic process | 16/300 | 360/17913 | 0.0004 | 0.0043 | 16 |
| GO:0010324 | membrane invagination | 6/300 | 58/17913 | 0.0004 | 0.0044 | 6 |
| GO:1904589 | regulation of protein import | 6/300 | 58/17913 | 0.0004 | 0.0044 | 6 |
| GO:0050851 | antigen receptor-mediated signaling pathway | 12/300 | 224/17913 | 0.0004 | 0.0045 | 12 |
| GO:0072522 | purine-containing compound biosynthetic process | 14/300 | 291/17913 | 0.0004 | 0.0045 | 14 |
| GO:0035690 | cellular response to drug | 16/300 | 362/17913 | 0.0004 | 0.0045 | 16 |
| GO:0090130 | tissue migration | 16/300 | 363/17913 | 0.0004 | 0.0047 | 16 |
| GO:1990748 | cellular detoxification | 8/300 | 107/17913 | 0.0004 | 0.0047 | 8 |
| GO:0016051 | carbohydrate biosynthetic process | 11/300 | 194/17913 | 0.0004 | 0.0047 | 11 |
| GO:0000715 | nucleotide-excision repair, DNA damage recognition | 4/300 | 22/17913 | 0.0004 | 0.0047 | 4 |
| GO:1902883 | negative regulation of response to oxidative stress | 6/300 | 59/17913 | 0.0004 | 0.0048 | 6 |
| GO:2001056 | positive regulation of cysteine-type endopeptidase activity | 9/300 | 135/17913 | 0.0005 | 0.0048 | 9 |
| GO:1901293 | nucleoside phosphate biosynthetic process | 16/300 | 365/17913 | 0.0005 | 0.0049 | 16 |
| GO:0051223 | regulation of protein transport | 24/300 | 677/17913 | 0.0005 | 0.0050 | 24 |
| GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 14/300 | 295/17913 | 0.0005 | 0.0050 | 14 |
| GO:0002706 | regulation of lymphocyte mediated immunity | 9/300 | 136/17913 | 0.0005 | 0.0050 | 9 |
| GO:1903305 | regulation of regulated secretory pathway | 9/300 | 136/17913 | 0.0005 | 0.0050 | 9 |
| GO:0045582 | positive regulation of T cell differentiation | 7/300 | 83/17913 | 0.0005 | 0.0050 | 7 |
| GO:0050727 | regulation of inflammatory response | 19/300 | 479/17913 | 0.0005 | 0.0051 | 19 |
| GO:0032869 | cellular response to insulin stimulus | 11/300 | 197/17913 | 0.0005 | 0.0052 | 11 |
| GO:0007417 | central nervous system development | 30/300 | 935/17913 | 0.0005 | 0.0052 | 30 |
| GO:0071417 | cellular response to organonitrogen compound | 21/300 | 559/17913 | 0.0005 | 0.0052 | 21 |
| GO:0070201 | regulation of establishment of protein localization | 25/300 | 723/17913 | 0.0005 | 0.0053 | 25 |
| GO:0072521 | purine-containing compound metabolic process | 21/300 | 560/17913 | 0.0005 | 0.0053 | 21 |
| GO:0071621 | granulocyte chemotaxis | 7/300 | 84/17913 | 0.0005 | 0.0053 | 7 |
| GO:0071677 | positive regulation of mononuclear cell migration | 4/300 | 23/17913 | 0.0005 | 0.0055 | 4 |
| GO:1904377 | positive regulation of protein localization to cell periphery | 6/300 | 61/17913 | 0.0005 | 0.0055 | 6 |
| GO:0030278 | regulation of ossification | 11/300 | 199/17913 | 0.0005 | 0.0056 | 11 |
| GO:0006898 | receptor-mediated endocytosis | 14/300 | 301/17913 | 0.0006 | 0.0059 | 14 |
| GO:0002639 | positive regulation of immunoglobulin production | 5/300 | 41/17913 | 0.0006 | 0.0059 | 5 |
| GO:0032623 | interleukin-2 production | 6/300 | 62/17913 | 0.0006 | 0.0060 | 6 |
| GO:0017038 | protein import | 9/300 | 140/17913 | 0.0006 | 0.0060 | 9 |
| GO:0061024 | membrane organization | 25/300 | 730/17913 | 0.0006 | 0.0060 | 25 |
| GO:0098655 | cation transmembrane transport | 25/300 | 730/17913 | 0.0006 | 0.0060 | 25 |
| GO:0001959 | regulation of cytokine-mediated signaling pathway | 10/300 | 170/17913 | 0.0006 | 0.0060 | 10 |
| GO:0097529 | myeloid leukocyte migration | 10/300 | 170/17913 | 0.0006 | 0.0060 | 10 |
| GO:0006913 | nucleocytoplasmic transport | 14/300 | 302/17913 | 0.0006 | 0.0060 | 14 |
| GO:0072507 | divalent inorganic cation homeostasis | 17/300 | 412/17913 | 0.0006 | 0.0061 | 17 |
| GO:0043491 | protein kinase B signaling | 13/300 | 268/17913 | 0.0006 | 0.0061 | 13 |
| GO:0000188 | inactivation of MAPK activity | 4/300 | 24/17913 | 0.0006 | 0.0062 | 4 |
| GO:0043433 | negative regulation of DNA-binding transcription factor activity | 10/300 | 171/17913 | 0.0006 | 0.0062 | 10 |
| GO:0051347 | positive regulation of transferase activity | 22/300 | 609/17913 | 0.0006 | 0.0062 | 22 |
| GO:0030183 | B cell differentiation | 8/300 | 113/17913 | 0.0006 | 0.0062 | 8 |
| GO:0098754 | detoxification | 8/300 | 113/17913 | 0.0006 | 0.0062 | 8 |
| GO:0046637 | regulation of alpha-beta T cell differentiation | 6/300 | 63/17913 | 0.0006 | 0.0063 | 6 |
| GO:0071277 | cellular response to calcium ion | 6/300 | 63/17913 | 0.0006 | 0.0063 | 6 |
| GO:2000117 | negative regulation of cysteine-type endopeptidase activity | 7/300 | 87/17913 | 0.0006 | 0.0063 | 7 |
| GO:0006816 | calcium ion transport | 17/300 | 415/17913 | 0.0007 | 0.0065 | 17 |
| GO:0050792 | regulation of viral process | 11/300 | 204/17913 | 0.0007 | 0.0066 | 11 |
| GO:0001933 | negative regulation of protein phosphorylation | 17/300 | 416/17913 | 0.0007 | 0.0067 | 17 |
| GO:0002286 | T cell activation involved in immune response | 7/300 | 88/17913 | 0.0007 | 0.0067 | 7 |
| GO:0010634 | positive regulation of epithelial cell migration | 10/300 | 173/17913 | 0.0007 | 0.0067 | 10 |
| GO:0002323 | natural killer cell activation involved in immune response | 3/300 | 11/17913 | 0.0007 | 0.0067 | 3 |
| GO:0019321 | pentose metabolic process | 3/300 | 11/17913 | 0.0007 | 0.0067 | 3 |
| GO:0140052 | cellular response to oxidised low-density lipoprotein particle stimulus | 3/300 | 11/17913 | 0.0007 | 0.0067 | 3 |
| GO:0045670 | regulation of osteoclast differentiation | 6/300 | 64/17913 | 0.0007 | 0.0067 | 6 |
| GO:0000086 | G2/M transition of mitotic cell cycle | 12/300 | 238/17913 | 0.0007 | 0.0068 | 12 |
| GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 5/300 | 43/17913 | 0.0007 | 0.0070 | 5 |
| GO:1903532 | positive regulation of secretion by cell | 16/300 | 381/17913 | 0.0007 | 0.0070 | 16 |
| GO:0002824 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 7/300 | 89/17913 | 0.0007 | 0.0070 | 7 |
| GO:0045672 | positive regulation of osteoclast differentiation | 4/300 | 25/17913 | 0.0007 | 0.0070 | 4 |
| GO:0097066 | response to thyroid hormone | 4/300 | 25/17913 | 0.0007 | 0.0070 | 4 |
| GO:0006801 | superoxide metabolic process | 6/300 | 65/17913 | 0.0008 | 0.0072 | 6 |
| GO:0051346 | negative regulation of hydrolase activity | 17/300 | 420/17913 | 0.0008 | 0.0072 | 17 |
| GO:0006790 | sulfur compound metabolic process | 15/300 | 346/17913 | 0.0008 | 0.0073 | 15 |
| GO:0051896 | regulation of protein kinase B signaling | 12/300 | 241/17913 | 0.0008 | 0.0074 | 12 |
| GO:0097237 | cellular response to toxic substance | 12/300 | 241/17913 | 0.0008 | 0.0074 | 12 |
| GO:1900180 | regulation of protein localization to nucleus | 8/300 | 117/17913 | 0.0008 | 0.0074 | 8 |
| GO:0043524 | negative regulation of neuron apoptotic process | 9/300 | 146/17913 | 0.0008 | 0.0075 | 9 |
| GO:0002708 | positive regulation of lymphocyte mediated immunity | 7/300 | 91/17913 | 0.0008 | 0.0078 | 7 |
| GO:0007051 | spindle organization | 9/300 | 147/17913 | 0.0008 | 0.0078 | 9 |
| GO:0010951 | negative regulation of endopeptidase activity | 11/300 | 210/17913 | 0.0009 | 0.0080 | 11 |
| GO:2000679 | positive regulation of transcription regulatory region DNA binding | 4/300 | 26/17913 | 0.0009 | 0.0080 | 4 |
| GO:0048589 | developmental growth | 22/300 | 624/17913 | 0.0009 | 0.0080 | 22 |
| GO:1902600 | proton transmembrane transport | 9/300 | 148/17913 | 0.0009 | 0.0082 | 9 |
| GO:0051928 | positive regulation of calcium ion transport | 8/300 | 119/17913 | 0.0009 | 0.0082 | 8 |
| GO:0070227 | lymphocyte apoptotic process | 6/300 | 67/17913 | 0.0009 | 0.0082 | 6 |
| GO:0001503 | ossification | 16/300 | 388/17913 | 0.0009 | 0.0082 | 16 |
| GO:0051701 | interaction with host | 11/300 | 211/17913 | 0.0009 | 0.0082 | 11 |
| GO:0043409 | negative regulation of MAPK cascade | 10/300 | 179/17913 | 0.0009 | 0.0082 | 10 |
| GO:0032103 | positive regulation of response to external stimulus | 14/300 | 315/17913 | 0.0009 | 0.0083 | 14 |
| GO:0072657 | protein localization to membrane | 20/300 | 545/17913 | 0.0009 | 0.0083 | 20 |
| GO:0042308 | negative regulation of protein import into nucleus | 3/300 | 12/17913 | 0.0009 | 0.0083 | 3 |
| GO:0051238 | sequestering of metal ion | 3/300 | 12/17913 | 0.0009 | 0.0083 | 3 |
| GO:1904590 | negative regulation of protein import | 3/300 | 12/17913 | 0.0009 | 0.0083 | 3 |
| GO:0045621 | positive regulation of lymphocyte differentiation | 7/300 | 93/17913 | 0.0010 | 0.0086 | 7 |
| GO:0046364 | monosaccharide biosynthetic process | 7/300 | 93/17913 | 0.0010 | 0.0086 | 7 |
| GO:1903076 | regulation of protein localization to plasma membrane | 7/300 | 93/17913 | 0.0010 | 0.0086 | 7 |
| GO:0071674 | mononuclear cell migration | 6/300 | 68/17913 | 0.0010 | 0.0086 | 6 |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 16/300 | 392/17913 | 0.0010 | 0.0089 | 16 |
| GO:0007160 | cell-matrix adhesion | 11/300 | 214/17913 | 0.0010 | 0.0089 | 11 |
| GO:0032673 | regulation of interleukin-4 production | 4/300 | 27/17913 | 0.0010 | 0.0089 | 4 |
| GO:0090068 | positive regulation of cell cycle process | 13/300 | 283/17913 | 0.0010 | 0.0090 | 13 |
| GO:0002821 | positive regulation of adaptive immune response | 7/300 | 94/17913 | 0.0010 | 0.0090 | 7 |
| GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 7/300 | 94/17913 | 0.0010 | 0.0090 | 7 |
| GO:0032680 | regulation of tumor necrosis factor production | 9/300 | 151/17913 | 0.0010 | 0.0090 | 9 |
| GO:0042552 | myelination | 8/300 | 122/17913 | 0.0010 | 0.0092 | 8 |
| GO:0046390 | ribose phosphate biosynthetic process | 13/300 | 284/17913 | 0.0010 | 0.0093 | 13 |
| GO:0030168 | platelet activation | 9/300 | 152/17913 | 0.0011 | 0.0094 | 9 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 17/300 | 434/17913 | 0.0011 | 0.0095 | 17 |
| GO:0030162 | regulation of proteolysis | 25/300 | 762/17913 | 0.0011 | 0.0095 | 25 |
| GO:0002204 | somatic recombination of immunoglobulin genes involved in immune response | 5/300 | 47/17913 | 0.0011 | 0.0095 | 5 |
| GO:0002208 | somatic diversification of immunoglobulins involved in immune response | 5/300 | 47/17913 | 0.0011 | 0.0095 | 5 |
| GO:0043370 | regulation of CD4-positive, alpha-beta T cell differentiation | 5/300 | 47/17913 | 0.0011 | 0.0095 | 5 |
| GO:0045190 | isotype switching | 5/300 | 47/17913 | 0.0011 | 0.0095 | 5 |
| GO:0045815 | positive regulation of gene expression, epigenetic | 5/300 | 47/17913 | 0.0011 | 0.0095 | 5 |
| GO:0046638 | positive regulation of alpha-beta T cell differentiation | 5/300 | 47/17913 | 0.0011 | 0.0095 | 5 |
| GO:0043393 | regulation of protein binding | 11/300 | 217/17913 | 0.0011 | 0.0097 | 11 |
| GO:0050871 | positive regulation of B cell activation | 6/300 | 70/17913 | 0.0011 | 0.0097 | 6 |
| GO:0042692 | muscle cell differentiation | 15/300 | 359/17913 | 0.0011 | 0.0097 | 15 |
| GO:0036296 | response to increased oxygen levels | 4/300 | 28/17913 | 0.0011 | 0.0099 | 4 |
| GO:0090383 | phagosome acidification | 4/300 | 28/17913 | 0.0011 | 0.0099 | 4 |
| GO:0042177 | negative regulation of protein catabolic process | 8/300 | 124/17913 | 0.0012 | 0.0099 | 8 |